iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066531

Ensembl Protein ID

ENSMPUP00000014726.1

UniProt Accession

M3YTR6; M3YTR6_MUSPF

Genbank Protein ID

ENSMPUP00000014726

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01007016

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000014837.1	ENSMPUT00000014961.1	ENSMPUP00000014726.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	93.18	0.00e+00	2473.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSAEAGEGIT FSVPPFAEGG SCRRGGAAVA VEDEESQLPP PGSFWNVETA AAPGTGCPAA 60
TSGSSATRCR GNSSSGGGRR TTVAYVINEA SQGQLVVAES EALQSLREAC ETVGATLETL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCGCCG AAGCGGGCGA GGGCATCACT TTCTCGGTGC CACCCTTCGC CGAGGGTGGA 60
AGCTGCCGGA GGGGAGGAGC GGCGGTGGCA GTCGAGGACG AAGAGAGCCA GCTACCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	96.27	0.00e+00	2377.00
IUUC-Apl-003713	Anas platyrhynchos	87.04	0.00e+00	2067.00
IUUC-Aca-005331	Anolis carolinensis	85.39	0.00e+00	2067.00
IUUC-Ame-011158	Astyanax mexicanus	72.04	0.00e+00	1845.00
IUUC-Bta-012770	Bos taurus	93.57	0.00e+00	2456.00
IUUC-Cja-019656	Callithrix jacchus	92.82	0.00e+00	2453.00
IUUC-Cfa-020488	Canis familiaris	95.43	0.00e+00	2496.00
IUUC-Cpo-022516	Cavia porcellus	91.23	0.00e+00	2288.00
IUUC-Csa-023104	Chlorocebus sabaeus	94.41	0.00e+00	2283.00
IUUC-Cho-024379	Choloepus hoffmanni	86.72	0.00e+00	1226.00
IUUC-Dre-028836	Danio rerio	73.21	0.00e+00	1866.00
IUUC-Dno-029842	Dasypus novemcinctus	91.52	0.00e+00	2191.00
IUUC-Dor-030990	Dipodomys ordii	92.14	0.00e+00	1918.00
IUUC-Ete-032693	Echinops telfairi	87.34	0.00e+00	1031.00
IUUC-Eca-033337	Equus caballus	93.03	0.00e+00	2307.00
IUUC-Eeu-034602	Erinaceus europaeus	76.22	0.00e+00	1097.00
IUUC-Fca-035954	Felis catus	94.47	0.00e+00	1949.00
IUUC-Fal-037358	Ficedula albicollis	86.50	0.00e+00	2098.00
IUUC-Gmo-038836	Gadus morhua	76.43	0.00e+00	1753.00
IUUC-Gga-040443	Gallus gallus	85.40	0.00e+00	2225.00
IUUC-Gac-041634	Gasterosteus aculeatus	73.56	0.00e+00	1933.00
IUUC-Ggo-045263	Gorilla gorilla	91.29	0.00e+00	2386.00
IUUC-Hsa-046906	Homo sapiens	93.18	0.00e+00	2469.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	94.21	0.00e+00	1091.00
IUUC-Lch-050213	Latimeria chalumnae	76.60	0.00e+00	1794.00
IUUC-Loc-051829	Lepisosteus oculatus	70.34	0.00e+00	1864.00
IUUC-Laf-053538	Loxodonta africana	92.46	0.00e+00	2452.00
IUUC-Mcc-054776	Macaca mulatta	93.18	0.00e+00	2489.00
IUUC-Mga-059636	Meleagris gallopavo	86.74	0.00e+00	2126.00
IUUC-Mmr-061323	Microcebus murinus	93.26	0.00e+00	2425.00
IUUC-Mdo-062146	Monodelphis domestica	87.91	0.00e+00	2305.00
IUUC-Mmu-064022	Mus musculus	90.23	0.00e+00	2388.00
IUUC-Mlu-068181	Myotis lucifugus	88.48	0.00e+00	2371.00
IUUC-Nle-069758	Nomascus leucogenys	94.25	0.00e+00	2278.00
IUUC-Opr-070531	Ochotona princeps	84.59	0.00e+00	1451.00
IUUC-Ont-072014	Oreochromis niloticus	75.19	0.00e+00	1895.00
IUUC-Oan-073169	Ornithorhynchus anatinus	91.02	0.00e+00	2226.00
IUUC-Ocu-074050	Oryctolagus cuniculus	89.04	0.00e+00	2133.00
IUUC-Ola-086941	Oryzias latipes	77.14	0.00e+00	1529.00
IUUC-Oga-088796	Otolemur garnettii	92.47	0.00e+00	2415.00
IUUC-Oar-090445	Ovis aries	94.19	0.00e+00	2290.00
IUUC-Ptr-090846	Pan troglodytes	93.04	0.00e+00	2482.00
IUUC-Pan-091986	Papio anubis	93.25	0.00e+00	2491.00
IUUC-Psi-093805	Pelodiscus sinensis	86.35	0.00e+00	2214.00
IUUC-Pfo-097301	Poecilia formosa	72.49	0.00e+00	1928.00
IUUC-Pab-097662	Pongo abelii	94.12	0.00e+00	2433.00
IUUC-Pca-100755	Procavia capensis	93.70	0.00e+00	719.00
IUUC-Pva-102280	Pteropus vampyrus	84.22	0.00e+00	2248.00
IUUC-Rno-105547	Rattus norvegicus	89.16	0.00e+00	2370.00
IUUC-Sha-106859	Sarcophilus harrisii	86.95	0.00e+00	2247.00
IUUC-Sar-113714	Sorex araneus	81.00	0.00e+00	1127.00
IUUC-Tgu-117116	Taeniopygia guttata	85.40	0.00e+00	2174.00
IUUC-Tru-118088	Takifugu rubripes	71.76	0.00e+00	1940.00
IUUC-Tsy-119616	Tarsius syrichta	87.64	0.00e+00	1976.00
IUUC-Tni-120284	Tetraodon nigroviridis	73.29	0.00e+00	1884.00
IUUC-Tbe-127900	Tupaia belangeri	88.45	0.00e+00	837.00
IUUC-Ttr-128294	Tursiops truncatus	83.05	0.00e+00	2120.00
IUUC-Vpa-130470	Vicugna pacos	91.98	0.00e+00	1326.00
IUUC-Xtr-132396	Xenopus tropicalis	73.96	0.00e+00	1975.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence