iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053809

UUCD1 version

UUC-LoA-00436

Ensembl Protein ID

ENSLAFP00000010702.2

UniProt Accession

G3TA38; G3TA38_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000012799.2	ENSLAFT00000012798.2	ENSLAFP00000010702.2
ENSLAFG00000012799.2	ENSLAFT00000032241.1	ENSLAFP00000025036.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-30	102.3	184	218
UBD/Beta-Prp	1.30e-46	159.5	42	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlrt 32
           gH  ++ ++++ +    +l+++s D  +k+WD+r+
   Q: 184  GHRQEILAVSWsPRyeYILATASADSRVKLWDVRR 218
           89*********94344668*************986 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgk.ilvtgseDrtikvwdls........tgkcvhtlk.....ghedsvlslsfsp.sgdklvsGshdrtirvwdle 124
           h ++v++++++p +  ++++g++D++i ++dl+        t+k v ++       h++sv +++++p ++  + s s d+t+++wd++
   Q: 42   HGSGVNTLDIEPVEGrYMLSGGSDGVIVLYDLQnssrqpyyTCKAVCSIGrshpdVHKYSVETVQWYPhDTGMFTSSSFDKTLKIWDTN 130
           67789999999987769999999999999999988888877666666665667778999999999999666999999999999999999 PP
   S: 125  tgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq. 210
           t q    ++ +++    +++   ++ +l++ G+   +v+l dlk+g++ + l+g h + +  +s+++     l+++s d++vklwd++ 
   Q: 131  TLQAADVFNFEETVYSHHMSPVATKhCLVAVGTRGPKVQLCDLKSGSCSHILQG-HRQEILAVSWSPRYeYILATASADSRVKLWDVRr 218
           999998555555555556666677778889999999999999999999999999.9999999999998745677899999999999998 PP
   S: 211  ...............tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
                          ++ +  + ++h+  v+ + f++++ +l++++ D+  r+W++ +g+++
   Q: 219  asgclitldqhngkkSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGENT 280
           76666666666555444446667778899999999999999999999999999999998876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MLGFLSARQA GLDDPLHLRR AESTRRVLGL ELNKDRDVER VHGSGVNTLD IEPVEGRYML 60
SGGSDGVIVL YDLQNSSRQP YYTCKAVCSI GRSHPDVHKY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTGGGT TTTTATCTGC GCGACAAGCC GGTTTGGACG ACCCTCTTCA CCTCCGGCGA 60
GCGGAGTCCA CACGGAGGTA AAGAACGCCT TACTTTTTTC TCCAACAGGC CAATTAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	31.48	5.00e-37	149.00
IUUC-Aml-002201	Ailuropoda melanoleuca	94.46	0.00e+00	786.00
IUUC-Atr-002784	Amborella trichopoda	36.60	9.00e-41	160.00
IUUC-Apl-003202	Anas platyrhynchos	81.40	0.00e+00	668.00
IUUC-Aca-004708	Anolis carolinensis	82.47	1.00e-178	618.00
IUUC-Aly-006144	Arabidopsis lyrata	39.61	9.00e-45	174.00
IUUC-Ath-006673	Arabidopsis thaliana	40.67	3.00e-46	179.00
IUUC-Acl-008195	Aspergillus clavatus	38.64	6.00e-43	168.00
IUUC-Afl-008406	Aspergillus flavus	36.84	2.00e-38	153.00
IUUC-Afu-008759	Aspergillus fumigatus	36.60	5.00e-40	158.00
IUUC-Ani-009380	Aspergillus nidulans	34.98	5.00e-41	161.00
IUUC-Ang-009820	Aspergillus niger	36.36	1.00e-38	153.00
IUUC-Aor-010092	Aspergillus oryzae	37.36	2.00e-43	170.00
IUUC-Ate-010491	Aspergillus terreus	36.65	1.00e-44	174.00
IUUC-Bta-012825	Bos taurus	94.96	0.00e+00	796.00
IUUC-Bci-013856	Botrytis cinerea	32.96	3.00e-53	202.00
IUUC-Bdi-014899	Brachypodium distachyon	33.17	2.00e-64	239.00
IUUC-Bol-015337	Brassica oleracea	38.36	8.00e-45	174.00
IUUC-Bra-018089	Brassica rapa	37.93	2.00e-45	176.00
IUUC-Cja-018725	Callithrix jacchus	93.20	0.00e+00	780.00
IUUC-Cfa-021162	Canis familiaris	94.71	0.00e+00	786.00
IUUC-Cpo-022190	Cavia porcellus	92.95	0.00e+00	780.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.14	8.00e-40	158.00
IUUC-Csa-023610	Chlorocebus sabaeus	94.71	0.00e+00	790.00
IUUC-Cho-024689	Choloepus hoffmanni	93.53	0.00e+00	719.00
IUUC-Cin-025324	Ciona intestinalis	40.05	7.00e-81	293.00
IUUC-Csv-026059	Ciona savignyi	38.48	1.00e-73	270.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	34.07	4.00e-39	155.00
IUUC-Cme-027182	Cyanidioschyzon merolae	28.05	3.00e-13	70.50
IUUC-Dre-028696	Danio rerio	72.75	5.00e-179	620.00
IUUC-Dno-029102	Dasypus novemcinctus	95.47	0.00e+00	792.00
IUUC-Dor-030361	Dipodomys ordii	76.07	2.00e-176	611.00
IUUC-Dse-031167	Dothistroma septosporum	29.75	2.00e-45	176.00
IUUC-Ete-032856	Echinops telfairi	77.08	1.00e-179	621.00
IUUC-Eca-033611	Equus caballus	95.28	0.00e+00	678.00
IUUC-Eeu-034583	Erinaceus europaeus	72.54	1.00e-164	572.00
IUUC-Fca-036481	Felis catus	93.70	0.00e+00	782.00
IUUC-Fal-037327	Ficedula albicollis	80.00	2.00e-167	581.00
IUUC-Fox-037684	Fusarium oxysporum	31.06	5.00e-44	171.00
IUUC-Fso-038306	Fusarium solani	31.83	5.00e-55	208.00
IUUC-Gmo-039043	Gadus morhua	69.70	4.00e-168	583.00
IUUC-Ggr-039783	Gaeumannomyces graminis	28.77	2.00e-39	156.00
IUUC-Gga-041085	Gallus gallus	86.49	0.00e+00	642.00
IUUC-Gac-042328	Gasterosteus aculeatus	67.83	4.00e-161	560.00
IUUC-Gma-043004	Glycine max	32.51	4.00e-58	218.00
IUUC-Ggo-045627	Gorilla gorilla	86.32	0.00e+00	716.00
IUUC-Hsa-046028	Homo sapiens	94.71	0.00e+00	790.00
IUUC-Hvu-047678	Hordeum vulgare	32.17	1.00e-35	143.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	94.96	0.00e+00	793.00
IUUC-Kpa-049386	Komagataella pastoris	29.95	9.00e-44	171.00
IUUC-Lch-050590	Latimeria chalumnae	79.31	7.00e-162	562.00
IUUC-Lpe-051725	Leersia perrieri	33.44	5.00e-36	144.00
IUUC-Loc-051788	Lepisosteus oculatus	75.51	0.00e+00	629.00
IUUC-Lma-053082	Leptosphaeria maculans	33.89	2.00e-54	206.00
IUUC-Mcc-054998	Macaca mulatta	94.31	1.00e-161	561.00
IUUC-Meu-055929	Macropus eugenii	77.89	0.00e+00	640.00
IUUC-Mor-057003	Magnaporthe oryzae	33.53	8.00e-48	184.00
IUUC-Mtr-057921	Medicago truncatula	31.46	2.00e-56	213.00
IUUC-Mga-059449	Meleagris gallopavo	65.98	5.00e-126	443.00
IUUC-Mmr-061609	Microcebus murinus	91.07	0.00e+00	736.00
IUUC-Mdo-062564	Monodelphis domestica	86.43	0.00e+00	727.00
IUUC-Mmu-063904	Mus musculus	90.18	0.00e+00	758.00
IUUC-Mac-064716	Musa acuminata	37.95	1.00e-41	164.00
IUUC-Mpu-066617	Mustela putorius furo	94.96	0.00e+00	793.00
IUUC-Mlu-067054	Myotis lucifugus	92.44	0.00e+00	777.00
IUUC-Nfi-068467	Neosartorya fischeri	37.30	2.00e-34	139.00
IUUC-Nle-069731	Nomascus leucogenys	94.71	0.00e+00	790.00
IUUC-Opr-070297	Ochotona princeps	68.20	7.00e-88	317.00
IUUC-Ont-072558	Oreochromis niloticus	71.07	2.00e-166	578.00
IUUC-Oan-072864	Ornithorhynchus anatinus	89.47	7.00e-28	114.00
IUUC-Ocu-074415	Oryctolagus cuniculus	94.46	0.00e+00	790.00
IUUC-Oba-075759	Oryza barthii	41.05	2.00e-43	169.00
IUUC-Obr-076387	Oryza brachyantha	39.34	1.00e-45	177.00
IUUC-Ogl-077924	Oryza glaberrima	40.91	7.00e-18	83.60
IUUC-Ogu-078186	Oryza glumaepatula	34.20	2.00e-62	232.00
IUUC-Oin-079389	Oryza indica	33.43	1.00e-45	176.00
IUUC-Olo-080916	Oryza longistaminata	28.43	6.00e-17	80.10
IUUC-Ome-081471	Oryza meridionalis	40.53	9.00e-41	160.00
IUUC-Oni-082449	Oryza nivara	39.29	2.00e-40	160.00
IUUC-Opu-083210	Oryza punctata	40.53	3.00e-43	169.00
IUUC-Oru-085159	Oryza rufipogon	41.05	1.00e-43	170.00
IUUC-Osa-085926	Oryza sativa	41.22	5.00e-33	133.00
IUUC-Ola-087084	Oryzias latipes	69.27	5.00e-169	587.00
IUUC-Olu-087853	Ostreococcus lucimarinus	29.29	8.00e-40	157.00
IUUC-Oga-089008	Otolemur garnettii	93.48	0.00e+00	785.00
IUUC-Oar-089259	Ovis aries	94.96	0.00e+00	794.00
IUUC-Ptr-091112	Pan troglodytes	93.91	0.00e+00	780.00
IUUC-Pan-092303	Papio anubis	94.57	3.00e-70	256.00
IUUC-Psi-093050	Pelodiscus sinensis	83.96	0.00e+00	706.00
IUUC-Pma-094259	Petromyzon marinus	57.43	1.00e-129	456.00
IUUC-Pno-094798	Phaeosphaeria nodorum	31.41	1.00e-51	197.00
IUUC-Ppa-095477	Physcomitrella patens	32.09	3.00e-57	216.00
IUUC-Pfo-096855	Poecilia formosa	67.66	2.00e-164	571.00
IUUC-Pab-098096	Pongo abelii	93.95	0.00e+00	785.00
IUUC-Pop-098800	Populus trichocarpa	37.28	4.00e-46	178.00
IUUC-Pca-100187	Procavia capensis	97.09	2.00e-118	418.00
IUUC-Ppe-101759	Prunus persica	37.78	1.00e-44	173.00
IUUC-Pva-102438	Pteropus vampyrus	79.02	8.00e-93	333.00
IUUC-Pte-104197	Pyrenophora teres	33.62	7.00e-50	191.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	34.08	1.00e-49	190.00
IUUC-Rno-106087	Rattus norvegicus	91.44	0.00e+00	767.00
IUUC-Sce-106276	Saccharomyces cerevisiae	28.87	9.00e-14	71.60
IUUC-Sha-106831	Sarcophilus harrisii	82.91	0.00e+00	694.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	33.24	4.00e-57	214.00
IUUC-Spo-108294	Schizosaccharomyces pombe	37.06	5.00e-65	241.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	32.95	2.00e-51	196.00
IUUC-Smo-109008	Selaginella moellendorffii	40.30	8.00e-75	274.00
IUUC-Sit-110300	Setaria italica	30.14	1.00e-52	200.00
IUUC-Sly-111441	Solanum lycopersicum	30.96	3.00e-48	186.00
IUUC-Stu-111995	Solanum tuberosum	30.79	7.00e-48	184.00
IUUC-Sar-113196	Sorex araneus	84.03	2.00e-128	452.00
IUUC-Sbi-113790	Sorghum bicolor	40.00	5.00e-43	168.00
IUUC-Ssc-115609	Sus scrofa	94.46	0.00e+00	795.00
IUUC-Tgu-116927	Taeniopygia guttata	81.45	0.00e+00	674.00
IUUC-Tru-118164	Takifugu rubripes	69.73	4.00e-173	600.00
IUUC-Tsy-119151	Tarsius syrichta	89.17	0.00e+00	739.00
IUUC-Tni-120896	Tetraodon nigroviridis	69.00	9.00e-164	569.00
IUUC-Tca-121592	Theobroma cacao	37.78	3.00e-45	175.00
IUUC-Tre-122023	Trichoderma reesei	35.76	2.00e-50	193.00
IUUC-Tvi-122507	Trichoderma virens	36.68	5.00e-51	195.00
IUUC-Tae-125276	Triticum aestivum	33.57	3.00e-60	225.00
IUUC-Tur-126092	Triticum urartu	30.62	5.00e-35	142.00
IUUC-Tbe-127422	Tupaia belangeri	71.16	5.00e-151	526.00
IUUC-Ttr-129097	Tursiops truncatus	92.44	0.00e+00	769.00
IUUC-Vda-130014	Verticillium dahliae	35.94	2.00e-49	190.00
IUUC-Vpa-130782	Vicugna pacos	95.21	0.00e+00	802.00
IUUC-Vvi-131494	Vitis vinifera	36.40	1.00e-44	174.00
IUUC-Xtr-132165	Xenopus tropicalis	78.38	0.00e+00	627.00
IUUC-Xma-133205	Xiphophorus maculatus	68.33	1.00e-167	582.00
IUUC-Yli-134614	Yarrowia lipolytica	33.92	1.00e-57	216.00
IUUC-Zma-135861	Zea mays	34.31	2.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence