iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005285

Ensembl Protein ID

ENSACAP00000003698.3

UniProt Accession

G1KC85; G1KC85_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ARHGAP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003717.3	ENSACAT00000003788.3	ENSACAP00000003698.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-11	43.8	725	778

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +k ++ y+ ea+++ eL+++ G v + + +++ + gWl+g  +l+gk+Gl+Pen+v+
   Q: 725  RKARAVYPCEAEHSSELSFQTGAVFEDV-HYSREPGWLEG--TLNGKKGLIPENYVQ 778
           57899***********************.***********..8************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGLQPLEFSD CYLDSPWFRE SVRAHEAELE KTNKFIKELL KDGKNLIAAT KSLSAAQRKF 60
ARSLRDFKFE FIGDAETDDE RCIDAALHEF ANFLKNLEEQ REIMALSVTE TLIKPLERFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCGGATTCT CCCAGACAGG AAGAAGCCAG GCCTTGAGGC CACAAATGCT AATCAAGGTG 60
ATTAATTACA ACATCCACAC TATGTATTTT AAGGCATCTA ATGGTTGCCA TATGTAAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0007010--P:cytoskeleton organization
GO:0043066--P:negative regulation of apoptotic process
GO:0007165--P:signal transduction

KEGG

acs:100558874

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	79.01	0.00e+00	1273.00
IUUC-Apl-003297	Anas platyrhynchos	81.07	0.00e+00	1241.00
IUUC-Bta-012379	Bos taurus	77.48	0.00e+00	1188.00
IUUC-Cel-018542	Caenorhabditis elegans	41.14	2.00e-130	460.00
IUUC-Cja-019182	Callithrix jacchus	77.86	0.00e+00	1220.00
IUUC-Cfa-021141	Canis familiaris	78.75	0.00e+00	1269.00
IUUC-Csa-023847	Chlorocebus sabaeus	77.82	0.00e+00	1134.00
IUUC-Cin-025725	Ciona intestinalis	39.30	1.00e-146	513.00
IUUC-Dre-027525	Danio rerio	59.80	0.00e+00	873.00
IUUC-Dno-029215	Dasypus novemcinctus	70.38	0.00e+00	797.00
IUUC-Dor-030308	Dipodomys ordii	70.84	0.00e+00	991.00
IUUC-Eca-033545	Equus caballus	78.58	0.00e+00	1134.00
IUUC-Fca-036457	Felis catus	78.50	0.00e+00	1263.00
IUUC-Fal-036703	Ficedula albicollis	81.05	0.00e+00	1261.00
IUUC-Gga-040830	Gallus gallus	80.79	0.00e+00	1269.00
IUUC-Gac-041728	Gasterosteus aculeatus	55.06	0.00e+00	828.00
IUUC-Ggo-044569	Gorilla gorilla	75.07	0.00e+00	1085.00
IUUC-Hsa-045658	Homo sapiens	78.37	0.00e+00	1210.00
IUUC-Loc-051740	Lepisosteus oculatus	62.06	0.00e+00	952.00
IUUC-Laf-053641	Loxodonta africana	78.22	0.00e+00	1222.00
IUUC-Mcc-055152	Macaca mulatta	78.63	0.00e+00	1254.00
IUUC-Mmr-061434	Microcebus murinus	78.20	0.00e+00	1138.00
IUUC-Mdo-062864	Monodelphis domestica	78.75	0.00e+00	1264.00
IUUC-Mmu-064061	Mus musculus	76.21	0.00e+00	1204.00
IUUC-Mlu-067375	Myotis lucifugus	77.07	0.00e+00	1110.00
IUUC-Nle-069319	Nomascus leucogenys	72.40	8.00e-171	592.00
IUUC-Ont-071443	Oreochromis niloticus	59.44	0.00e+00	902.00
IUUC-Oan-072978	Ornithorhynchus anatinus	74.78	0.00e+00	1007.00
IUUC-Ocu-074591	Oryctolagus cuniculus	73.58	0.00e+00	1102.00
IUUC-Ola-087508	Oryzias latipes	63.30	0.00e+00	777.00
IUUC-Oga-088922	Otolemur garnettii	74.19	4.00e-156	543.00
IUUC-Oar-089531	Ovis aries	77.74	0.00e+00	1202.00
IUUC-Ptr-091149	Pan troglodytes	78.12	0.00e+00	1203.00
IUUC-Pan-092591	Papio anubis	78.37	0.00e+00	1232.00
IUUC-Pma-094731	Petromyzon marinus	31.36	3.00e-19	91.30
IUUC-Pfo-097265	Poecilia formosa	59.21	0.00e+00	889.00
IUUC-Pab-097780	Pongo abelii	78.24	0.00e+00	1209.00
IUUC-Rno-104991	Rattus norvegicus	76.08	0.00e+00	1203.00
IUUC-Sha-107629	Sarcophilus harrisii	75.74	0.00e+00	1036.00
IUUC-Ssc-115511	Sus scrofa	62.25	5.00e-169	587.00
IUUC-Tgu-117458	Taeniopygia guttata	79.92	0.00e+00	1233.00
IUUC-Tru-117724	Takifugu rubripes	62.08	0.00e+00	770.00
IUUC-Tbe-128126	Tupaia belangeri	26.11	3.00e-06	47.40
IUUC-Ttr-129045	Tursiops truncatus	74.93	0.00e+00	1077.00
IUUC-Xtr-132112	Xenopus tropicalis	71.05	0.00e+00	1118.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence