iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059981

UUCD1 version

UUC-MeG-00457

Ensembl Protein ID

ENSMGAP00000011657.1

UniProt Accession

G1NF86; G1NF86_MELGA

Protein Name

Uncharacterized protein

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011162.1	ENSMGAT00000012537.1	ENSMGAP00000011657.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.09	0.00e+00	709.00	IUUC-Hsa-045784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FSSLLPAARN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPEVFKKIKE 60
LYETRYAKKS SEAPQPHRSP EALPIHSSYD RGSAVARTSI STPNIDYPTL YGKYLNGLGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTCCTCTC TGCTCCCCGC TGCTCGTGTT AGAATGATCG TTTGATGTTT GTCACTTTGT 60
TGAGTGATTG GTGTTCTCTG GTCTGGGTGG GTCGGTGGGT TCTGAGTCAT AGAGAACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	86.79	0.00e+00	691.00
IUUC-Apl-003765	Anas platyrhynchos	95.53	0.00e+00	746.00
IUUC-Ame-010763	Astyanax mexicanus	60.97	7.00e-134	470.00
IUUC-Bta-012369	Bos taurus	89.09	0.00e+00	709.00
IUUC-Cja-019450	Callithrix jacchus	88.28	0.00e+00	705.00
IUUC-Cfa-020933	Canis familiaris	88.83	0.00e+00	707.00
IUUC-Cpo-022112	Cavia porcellus	88.57	0.00e+00	707.00
IUUC-Csa-023913	Chlorocebus sabaeus	75.47	1.00e-156	545.00
IUUC-Dre-027609	Danio rerio	59.53	1.00e-128	452.00
IUUC-Dno-029664	Dasypus novemcinctus	88.94	1.00e-124	439.00
IUUC-Ete-032988	Echinops telfairi	83.87	6.00e-154	536.00
IUUC-Eca-034430	Equus caballus	88.28	0.00e+00	702.00
IUUC-Fca-035968	Felis catus	88.36	1.00e-153	535.00
IUUC-Fal-037449	Ficedula albicollis	91.82	0.00e+00	703.00
IUUC-Gmo-038925	Gadus morhua	60.37	6.00e-131	460.00
IUUC-Gga-040362	Gallus gallus	96.89	0.00e+00	765.00
IUUC-Gac-042353	Gasterosteus aculeatus	61.54	4.00e-125	441.00
IUUC-Ggo-044810	Gorilla gorilla	85.97	0.00e+00	676.00
IUUC-Hsa-045784	Homo sapiens	89.09	0.00e+00	709.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	89.66	0.00e+00	701.00
IUUC-Lch-049727	Latimeria chalumnae	70.76	3.00e-154	537.00
IUUC-Loc-052354	Lepisosteus oculatus	54.01	8.00e-108	383.00
IUUC-Laf-054261	Loxodonta africana	87.79	0.00e+00	700.00
IUUC-Mcc-054931	Macaca mulatta	88.83	0.00e+00	706.00
IUUC-Meu-056468	Macropus eugenii	91.67	0.00e+00	725.00
IUUC-Mmr-061181	Microcebus murinus	86.81	0.00e+00	670.00
IUUC-Mdo-062345	Monodelphis domestica	91.41	0.00e+00	721.00
IUUC-Mmu-063197	Mus musculus	86.77	0.00e+00	672.00
IUUC-Mpu-066275	Mustela putorius furo	88.05	0.00e+00	702.00
IUUC-Mlu-067194	Myotis lucifugus	88.37	0.00e+00	702.00
IUUC-Ont-072227	Oreochromis niloticus	61.01	4.00e-127	447.00
IUUC-Ola-086865	Oryzias latipes	60.21	5.00e-127	447.00
IUUC-Oga-088945	Otolemur garnettii	88.83	0.00e+00	706.00
IUUC-Oar-089412	Ovis aries	89.30	0.00e+00	706.00
IUUC-Ptr-091550	Pan troglodytes	79.26	4.00e-172	596.00
IUUC-Pan-092183	Papio anubis	88.83	0.00e+00	706.00
IUUC-Psi-093003	Pelodiscus sinensis	95.29	0.00e+00	744.00
IUUC-Pfo-096704	Poecilia formosa	60.10	1.00e-130	459.00
IUUC-Pab-097923	Pongo abelii	91.18	0.00e+00	709.00
IUUC-Pca-100249	Procavia capensis	77.25	8.00e-103	366.00
IUUC-Pva-102562	Pteropus vampyrus	86.97	0.00e+00	673.00
IUUC-Rno-105762	Rattus norvegicus	87.04	0.00e+00	675.00
IUUC-Sha-107253	Sarcophilus harrisii	93.09	0.00e+00	720.00
IUUC-Sar-113149	Sorex araneus	80.77	1.00e-119	422.00
IUUC-Ssc-115241	Sus scrofa	89.35	0.00e+00	712.00
IUUC-Tgu-116884	Taeniopygia guttata	92.35	0.00e+00	710.00
IUUC-Tru-118031	Takifugu rubripes	61.27	6.00e-132	463.00
IUUC-Tni-119766	Tetraodon nigroviridis	61.27	2.00e-126	445.00
IUUC-Ttr-128556	Tursiops truncatus	79.35	3.00e-170	590.00
IUUC-Xtr-131866	Xenopus tropicalis	82.70	0.00e+00	672.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence