iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061886

UUCD1 version

UUC-MoD-00519

Ensembl Protein ID

ENSMODP00000034452.2

UniProt Accession

F6ZWU0; F6ZWU0_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR90

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000024523.2	ENSMODT00000036040.2	ENSMODP00000034452.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-42	140.8	1480	1514
UBD/Beta-Prp	1.10e-97	327.0	1441	1653

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH+++v+ + f ++  + ++++ Dg+++vW+l++ 
   Q: 1480 GHKNKVNEVTFsPNeSHCATCGEDGSVRVWSLTSM 1514
           8***********7779***************9975 PP

UBD/Beta-Prp

   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
             v+s sf+   d  ++G+   t+   ++ +++ ++ + sgh+  vn v+++p+++ +++++ D+ vr+W+l +++l+ +++   ++
   Q: 1441 GAVVSASFDDCMDMGIVGTTAGTLWYINWAEKTNIR-LISGHKNKVNEVTFSPNESHCATCGEDGSVRVWSLTSMELVVQFQV-LNQ 1525
           568999999988999999999999998888888888.99*******************************************8.*** PP
   S: 182  svyslsfdsng......kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlql 262
           s  +l++++++      +++v+g  dgt+++++++++e+  + + h  +v+ + fs +++ ++sg +Dg + +  +r+g ++++l+ 
   Q: 1526 SCLCLAWSPSSsgrtdhQRVVAGYSDGTIRIFSISQTEMELKIHPHPVPVTAISFSVDGQTIISGDKDGIVAVSSSRTGITIQVLKD 1612
           *********99**************************************************************************** PP
   S: 263  hnssvisvav........lsfg.dnvlvlgsedskvniwkl 294
           h+ s i v          ++++ +   +++s+d++v iw+ 
   Q: 1613 HQGSPITVIQskskeyynFGLEgGELWLAVSADQRVSIWAS 1653
           **554444443555553333333444488888*******85 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDKTLKGTVY RIRGAIPAGN FIQLPKTSTQ SLGLTGRYLY LLFRPIPMKY FVVHLDVTTE 60
DSQVIRISFS NLFKEFKSTS TWLQFPFIYE ETTRPLKTSK TDLIGAAPNS VRWTCLQLDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGGCAACA TCCATTTCTG AATGTCTTCA AACACTTGAA GGTAGAAGAA TGGAAAAGGT 60
CGACAAAGGA GGGTGATGTG ACTACTATTA TGGTAATTTA TCATGATCAT GACTGCTTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	57.44	0.00e+00	2069.00
IUUC-Apl-003387	Anas platyrhynchos	61.43	0.00e+00	2060.00
IUUC-Aca-005235	Anolis carolinensis	61.62	0.00e+00	1958.00
IUUC-Ame-011595	Astyanax mexicanus	53.18	0.00e+00	1544.00
IUUC-Bta-012328	Bos taurus	56.87	0.00e+00	1994.00
IUUC-Cja-019058	Callithrix jacchus	54.85	0.00e+00	1044.00
IUUC-Cfa-020934	Canis familiaris	55.28	0.00e+00	1915.00
IUUC-Cpo-022025	Cavia porcellus	57.12	0.00e+00	2044.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	30.22	2.00e-72	268.00
IUUC-Csa-023022	Chlorocebus sabaeus	57.19	0.00e+00	2037.00
IUUC-Cin-025133	Ciona intestinalis	37.72	0.00e+00	1272.00
IUUC-Csv-025816	Ciona savignyi	37.04	0.00e+00	1156.00
IUUC-Dre-028823	Danio rerio	49.95	0.00e+00	1765.00
IUUC-Dno-029211	Dasypus novemcinctus	65.27	0.00e+00	888.00
IUUC-Dor-030211	Dipodomys ordii	57.33	0.00e+00	1754.00
IUUC-Ete-032363	Echinops telfairi	50.34	0.00e+00	815.00
IUUC-Eca-034296	Equus caballus	58.11	0.00e+00	2051.00
IUUC-Eeu-035226	Erinaceus europaeus	47.90	0.00e+00	733.00
IUUC-Fca-035384	Felis catus	57.70	0.00e+00	2067.00
IUUC-Fal-037660	Ficedula albicollis	59.38	0.00e+00	2011.00
IUUC-Gga-040666	Gallus gallus	63.50	0.00e+00	1543.00
IUUC-Gac-041358	Gasterosteus aculeatus	50.78	0.00e+00	1780.00
IUUC-Ggo-045121	Gorilla gorilla	57.35	0.00e+00	2045.00
IUUC-Hsa-046289	Homo sapiens	57.11	0.00e+00	2000.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	57.72	0.00e+00	1959.00
IUUC-Lch-050009	Latimeria chalumnae	57.70	0.00e+00	1993.00
IUUC-Loc-052629	Lepisosteus oculatus	53.78	0.00e+00	968.00
IUUC-Mcc-055834	Macaca mulatta	52.83	0.00e+00	1771.00
IUUC-Meu-056162	Macropus eugenii	77.25	0.00e+00	1039.00
IUUC-Mga-060167	Meleagris gallopavo	59.24	0.00e+00	1948.00
IUUC-Mmr-060761	Microcebus murinus	65.02	1.00e-123	436.00
IUUC-Mmu-063652	Mus musculus	57.98	0.00e+00	2110.00
IUUC-Mlu-068141	Myotis lucifugus	58.63	0.00e+00	2064.00
IUUC-Nle-069133	Nomascus leucogenys	52.89	0.00e+00	1203.00
IUUC-Ont-072496	Oreochromis niloticus	54.05	0.00e+00	1934.00
IUUC-Oan-072833	Ornithorhynchus anatinus	57.13	0.00e+00	1968.00
IUUC-Ola-086564	Oryzias latipes	49.34	0.00e+00	1755.00
IUUC-Oga-088919	Otolemur garnettii	58.42	0.00e+00	1754.00
IUUC-Oar-089946	Ovis aries	56.04	0.00e+00	1078.00
IUUC-Ptr-090755	Pan troglodytes	59.52	0.00e+00	1743.00
IUUC-Pan-092054	Papio anubis	56.98	0.00e+00	2027.00
IUUC-Psi-093467	Pelodiscus sinensis	68.65	0.00e+00	2472.00
IUUC-Pma-094573	Petromyzon marinus	42.47	0.00e+00	1459.00
IUUC-Pfo-096849	Poecilia formosa	48.50	0.00e+00	1620.00
IUUC-Pab-098320	Pongo abelii	56.36	0.00e+00	1777.00
IUUC-Pca-100172	Procavia capensis	54.61	0.00e+00	1840.00
IUUC-Pva-102772	Pteropus vampyrus	58.06	0.00e+00	1127.00
IUUC-Rno-105046	Rattus norvegicus	57.67	0.00e+00	2121.00
IUUC-Sha-107094	Sarcophilus harrisii	87.27	0.00e+00	3244.00
IUUC-Ssc-116257	Sus scrofa	55.21	0.00e+00	1888.00
IUUC-Tgu-117323	Taeniopygia guttata	56.81	0.00e+00	1684.00
IUUC-Tru-118717	Takifugu rubripes	48.86	0.00e+00	1669.00
IUUC-Tni-120108	Tetraodon nigroviridis	48.79	0.00e+00	1652.00
IUUC-Ttr-128378	Tursiops truncatus	66.56	0.00e+00	902.00
IUUC-Xtr-131760	Xenopus tropicalis	55.04	0.00e+00	1944.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence