iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115890

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU929630

Gene Name

UBE2U

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000003810.2	ENSSSCT00000004217.2	ENSSSCP00000004122.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.80e-36	123.0	9	141

Active Site

Position(s)	Description	Evidence
89	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkee 89
           l+++++el++++ +gi a p +e dl ewev i G ++t+++g +F+l+i+f+++Y+f PP v+f t  fhPnv++  G+ C+++l+++
   Q: 9    LQRDFQELKRNNYKGINAFPISE-DLLEWEVDIKGLQNTIWQGSFFQLTISFTSEYNFVPPVVRFRTIPFHPNVDPYtGRPCIDFLDNP 96
           799********************.9***************************************************99*********** PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeyk 134
           +kW+  ++++s+ll++q +l++p  e+p+n eaa++l k+++ y+
   Q: 97   RKWNRNYTLSSILLTLQVMLSNPVLENPVNLEAAQILMKDETLYR 141
           ****************************************99997 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MYSRAYILLQ RDFQELKRNN YKGINAFPIS EDLLEWEVDI KGLQNTIWQG SFFQLTISFT 60
SEYNFVPPVV RFRTIPFHPN VDPYTGRPCI DFLDNPRKWN RNYTLSSILL TLQVMLSNPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTACAGCA GAGCTTACAT ATTGCTGCAA AGAGACTTCC AAGAGTTGAA GAGGAACAAT 60
TATAAGGTGA GTACTGGAGA CCTGAAGGGT GTGTTTCATT GGAGTGGGAA TTTTAAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

ssc:100519034

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002211	Ailuropoda melanoleuca	65.40	2.00e-70	258.00
IUUC-Aca-004682	Anolis carolinensis	42.04	3.00e-52	197.00
IUUC-Bta-013054	Bos taurus	69.81	4.00e-123	433.00
IUUC-Cja-018784	Callithrix jacchus	55.09	7.00e-98	350.00
IUUC-Cfa-020877	Canis familiaris	69.60	8.00e-92	328.00
IUUC-Cpo-022462	Cavia porcellus	56.74	2.00e-56	211.00
IUUC-Csa-023486	Chlorocebus sabaeus	70.48	3.00e-95	340.00
IUUC-Cho-024685	Choloepus hoffmanni	47.35	2.00e-64	239.00
IUUC-Dno-029061	Dasypus novemcinctus	60.32	2.00e-106	378.00
IUUC-Ete-032233	Echinops telfairi	50.00	3.00e-63	234.00
IUUC-Eca-033400	Equus caballus	76.47	6.00e-55	205.00
IUUC-Fca-035778	Felis catus	70.13	8.00e-136	476.00
IUUC-Ggo-044718	Gorilla gorilla	61.92	1.00e-113	402.00
IUUC-Hsa-046798	Homo sapiens	61.30	1.00e-110	392.00
IUUC-Lch-050337	Latimeria chalumnae	40.35	3.00e-65	241.00
IUUC-Loc-051819	Lepisosteus oculatus	36.70	3.00e-54	205.00
IUUC-Laf-054536	Loxodonta africana	66.67	2.00e-92	331.00
IUUC-Mcc-055028	Macaca mulatta	60.68	2.00e-111	395.00
IUUC-Mmr-061623	Microcebus murinus	57.86	5.00e-97	347.00
IUUC-Mdo-062614	Monodelphis domestica	41.06	8.00e-63	233.00
IUUC-Mmu-063194	Mus musculus	52.52	4.00e-69	254.00
IUUC-Mpu-066467	Mustela putorius furo	68.97	7.00e-123	432.00
IUUC-Mlu-067976	Myotis lucifugus	62.11	4.00e-75	273.00
IUUC-Nle-069407	Nomascus leucogenys	60.99	7.00e-109	386.00
IUUC-Opr-070526	Ochotona princeps	61.63	1.00e-53	202.00
IUUC-Oan-073005	Ornithorhynchus anatinus	47.51	1.00e-51	196.00
IUUC-Ocu-074953	Oryctolagus cuniculus	57.68	4.00e-95	340.00
IUUC-Oga-089061	Otolemur garnettii	58.44	4.00e-109	387.00
IUUC-Oar-090147	Ovis aries	72.33	5.00e-130	456.00
IUUC-Ptr-090873	Pan troglodytes	57.99	2.00e-101	362.00
IUUC-Pan-091873	Papio anubis	70.04	3.00e-94	337.00
IUUC-Psi-093780	Pelodiscus sinensis	39.18	2.00e-37	149.00
IUUC-Pab-098662	Pongo abelii	72.25	3.00e-97	347.00
IUUC-Pca-100167	Procavia capensis	47.35	3.00e-57	215.00
IUUC-Pva-102119	Pteropus vampyrus	60.95	9.00e-57	213.00
IUUC-Rno-105522	Rattus norvegicus	42.22	8.00e-69	253.00
IUUC-Sar-113070	Sorex araneus	51.96	3.00e-56	210.00
IUUC-Tsy-119341	Tarsius syrichta	53.85	3.00e-75	274.00
IUUC-Tbe-127433	Tupaia belangeri	48.47	6.00e-67	247.00
IUUC-Ttr-128614	Tursiops truncatus	71.43	7.00e-126	442.00
IUUC-Vpa-130777	Vicugna pacos	68.63	6.00e-126	443.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence