iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000015718.3	ENSMMUT00000075688.1	ENSMMUP00000044525.1
ENSMMUG00000015718.3	ENSMMUT00000022067.3	ENSMMUP00000020643.3
ENSMMUG00000015718.3	ENSMMUT00000067557.1	ENSMMUP00000045213.1
ENSMMUG00000015718.3	ENSMMUT00000078028.1	ENSMMUP00000057492.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.60e-28	99.1	274	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           kvC  C+++g+d+ ++++Ce C++ +H  Clk++  eelp ++ w C+ Cr +
   Q: 274  KVCQACRKPGNDS-KMLVCETCDKGYHTFCLKPP-MEELPAHS-WKCKACRVC 323
           58*********87.6*******************.*******8.******965 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDSQKLPGED KDSEPAADGP AASEDPSATE SDLPNPHVGE VSVPSSGSPS LQETPQDCSG 60
GPVRRCALCN CGEPSLHGQR ELRRFELPFD WPRCPVVSPG GSPGPNEAVL PSEDLSQIGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGCC AGAAGCTGCC TGGTGAGGAT AAAGATTCAG AACCGGCAGG TAAGTAGGAC 60
AAATTCTTTG TTTGCTTTTA GATTTCACAG GCAACCTTAC ATTTCTGGTC CTGGCCCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0008284--P:positive regulation of cell proliferation
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001054	Aegilops tauschii	27.27	4.00e-13	70.10
IUUC-Aml-001806	Ailuropoda melanoleuca	93.18	0.00e+00	3655.00
IUUC-Aca-005364	Anolis carolinensis	52.09	0.00e+00	1170.00
IUUC-Ame-010612	Astyanax mexicanus	75.47	0.00e+00	917.00
IUUC-Bta-013011	Bos taurus	91.26	0.00e+00	3554.00
IUUC-Cja-019841	Callithrix jacchus	94.26	0.00e+00	3913.00
IUUC-Cfa-021131	Canis familiaris	92.54	0.00e+00	3677.00
IUUC-Cpo-021957	Cavia porcellus	89.55	0.00e+00	3684.00
IUUC-Csa-023722	Chlorocebus sabaeus	98.58	0.00e+00	3973.00
IUUC-Dno-029932	Dasypus novemcinctus	82.99	0.00e+00	2236.00
IUUC-Dor-030192	Dipodomys ordii	87.22	0.00e+00	1728.00
IUUC-Ete-032572	Echinops telfairi	85.92	0.00e+00	1944.00
IUUC-Eca-034166	Equus caballus	93.25	0.00e+00	758.00
IUUC-Eeu-034848	Erinaceus europaeus	89.35	0.00e+00	1264.00
IUUC-Fca-035424	Felis catus	92.57	0.00e+00	3690.00
IUUC-Fal-037179	Ficedula albicollis	64.62	0.00e+00	1111.00
IUUC-Gmo-038719	Gadus morhua	75.89	0.00e+00	821.00
IUUC-Gga-040815	Gallus gallus	58.36	0.00e+00	1850.00
IUUC-Gac-042436	Gasterosteus aculeatus	73.92	0.00e+00	903.00
IUUC-Ggo-044711	Gorilla gorilla	97.17	0.00e+00	3776.00
IUUC-Hsa-046567	Homo sapiens	96.77	0.00e+00	3850.00
IUUC-Itr-048510	Ictidomys tridecemlineatus	91.42	0.00e+00	3650.00
IUUC-Loc-051979	Lepisosteus oculatus	77.08	0.00e+00	965.00
IUUC-Laf-054377	Loxodonta africana	90.84	0.00e+00	3605.00
IUUC-Meu-055992	Macropus eugenii	74.82	0.00e+00	1284.00
IUUC-Mmr-061772	Microcebus murinus	89.55	0.00e+00	3651.00
IUUC-Mdo-062876	Monodelphis domestica	77.27	0.00e+00	747.00
IUUC-Mmu-063903	Mus musculus	87.58	0.00e+00	3400.00
IUUC-Mpu-066700	Mustela putorius furo	92.32	0.00e+00	3629.00
IUUC-Mlu-068180	Myotis lucifugus	91.47	0.00e+00	3709.00
IUUC-Nle-069362	Nomascus leucogenys	97.44	0.00e+00	3794.00
IUUC-Opr-070304	Ochotona princeps	86.77	0.00e+00	3386.00
IUUC-Ont-071881	Oreochromis niloticus	61.96	0.00e+00	1318.00
IUUC-Oan-073663	Ornithorhynchus anatinus	85.29	0.00e+00	835.00
IUUC-Ocu-074053	Oryctolagus cuniculus	87.80	0.00e+00	3662.00
IUUC-Ome-081892	Oryza meridionalis	35.96	3.00e-13	70.50
IUUC-Ola-086384	Oryzias latipes	57.63	0.00e+00	1244.00
IUUC-Oga-088450	Otolemur garnettii	91.28	0.00e+00	3954.00
IUUC-Oar-089975	Ovis aries	91.38	0.00e+00	1947.00
IUUC-Ptr-091073	Pan troglodytes	96.60	0.00e+00	3774.00
IUUC-Pan-092871	Papio anubis	94.59	0.00e+00	3965.00
IUUC-Pfo-097525	Poecilia formosa	73.91	0.00e+00	887.00
IUUC-Pab-097679	Pongo abelii	97.18	0.00e+00	3845.00
IUUC-Pca-100499	Procavia capensis	87.55	0.00e+00	2264.00
IUUC-Pva-102898	Pteropus vampyrus	92.47	0.00e+00	3565.00
IUUC-Rno-105660	Rattus norvegicus	87.83	0.00e+00	3509.00
IUUC-Sha-107431	Sarcophilus harrisii	77.96	0.00e+00	3066.00
IUUC-Sly-111765	Solanum lycopersicum	30.46	3.00e-23	103.00
IUUC-Sbi-113816	Sorghum bicolor	33.71	3.00e-13	70.90
IUUC-Ssc-115678	Sus scrofa	91.75	0.00e+00	3497.00
IUUC-Tru-117922	Takifugu rubripes	74.69	0.00e+00	919.00
IUUC-Tsy-118905	Tarsius syrichta	89.26	0.00e+00	1679.00
IUUC-Tbe-127625	Tupaia belangeri	87.39	2.00e-158	555.00
IUUC-Ttr-129162	Tursiops truncatus	89.99	0.00e+00	2060.00
IUUC-Xtr-132455	Xenopus tropicalis	61.81	0.00e+00	1214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence