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Tag Content
UUCD2 ID IUUC-Mcc-055464
UUCD1 version UUC-MaM-00899
Ensembl Protein ID ENSMMUP00000003305.2
UniProt Accession F7HH01; F7HH01_MACMU
Genbank Protein ID ENSMMUP00000003305
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03030911
Gene Name CUL7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000002451.3 ENSMMUT00000003496.3 ENSMMUP00000003305.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 5.80e-150 502.1 970 1518
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 70   nreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveL 156
            ++W+ freql++++++f      y+++           +++w+++++ed +++ll+l+++l+ a+R+++++++r+l++++++    
   Q: 970  PTFWPVFREQLCRHTRLF------YMVR-----------AQAWSQDMAED-RRSLLHLSSRLNGALRQEQNFADRFLPDDEAA---- 1034
           589***************......****...........***********.********************************.... PP
   S: 157  slnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllae 242
               +a++k+++Ea++++ +q++++++++ ++   + +++Yl+++ea +n++++  a++++++++t+Ll++ve+++++       ++
   Q: 1035 ----QALGKTCWEALVSPVVQNITSPDEDGVSPLgWLLEQYLECQEAVFNPQSRGPAFFSRVRRLTHLLVHVEPCEAP-------PP 1110
           ....**************************************************************************.......** PP
   S: 243  lvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlk 327
           + a++r k++++ +++++L++++l+  ++++l++++++++++q++++lt++++++d   +V+r++e +n lq+++se+F+++a+Fl 
   Q: 1111 VAATPRPKGRNRSHDWSSLATQGLPssIMRNLTRCWQAVVEKQVNNFLTSSWRDDD---FVPRYCEQFNILQNSSSELFGPRAAFLL 1194
           ************************999*****************************...**************************** PP
   S: 328  aldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLlsgksa 410
           al+++++ +++k ++lkaa+++E++Ar+iDq++++s ++g++e+e +aql+++l+++ ++s++++   Fe+yY++++a+RLl   ++
   Q: 1195 ALQNGCAGALLKLPFLKAAHVSEQFARHIDQQIQGSrIGGAQEMERLAQLQQCLQAVLIFSGLEIattFEHYYQHYMADRLLG--VV 1279
           ***********************************************************************************..** PP
   S: 411  sseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk............................................ 452
           ss++E++v+e++    g++f+++L ++M+q+l++S++l+rqF+                                            
   Q: 1280 SSWLEGAVLEQI----GPCFPNRLpQQMLQSLSTSKELQRQFHvyqlqrldqellkledtekkiqvghrdsgkeyksekeegagaaa 1362
           ************....*********************************************************************** PP
   S: 453  ............eekenteesesvelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLqWqh 515
                       e+++ ++e +++e+svlvLs+++Wp+a  ++t  ++++LP++l+ t++++++fY        le++s+R+LqW++
   Q: 1363 avdvtegeeeeeENEDLYYEGAMPEVSVLVLSRHCWPVAsiCHTlnPRTCLPSYLRGTLNRYSNFYnksqshpaLEQGSQRRLQWTW 1449
           **********98889999*********************9999899***************************************** PP
   S: 516  tlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkep 587
            lg+ael++    g+++l+Vst+Qm++LL++n+ ++vsve+l + ++l+e++L+ ++++L+ss+   +++++++
   Q: 1450 -LGWAELQF----GNQTLHVSTVQMWLLLYLNDLKAVSVESLLALSGLSEDMLNEAIGPLTSSRgpLDLHEQKD 1518
           .********....*************************************************997777776655 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MVGELRYREF RVPLGPGLHA YPDELIRQRV GHDGHPEYQI RWLILRRGDE GDGGSGQVDC 60
KAEHILLWMS KDEIYANCHK MLGEDGQVIG PSQESSGEVG ALDKSVLEEM ETDVKSLIQR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055464|E3,Cullin|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGACGTGTGG TGTGCTACTG CGGAAGGTGA ATGGCACAGC CATTATCCAG CTGCCGTCTA 60
AGAGGCAGAT GCAGGTGTGT ATGGGTATGG CTGGGAGGGG TCAGCAAAGG AGGAATTTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055464|E3,Cullin|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021097--CPH_domain
IPR031223--CUL7
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS50069--CULLIN_2
PS51284--DOC
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM01337--APC10
SM00884--Cullin_Nedd8
Gene Ontology

GO:1990393--C:3M complex
GO:0005813--C:centrosome
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0001837--P:epithelial to mesenchymal transition
GO:0000226--P:microtubule cytoskeleton organization
GO:0000281--P:mitotic cytokinesis
GO:0001890--P:placenta development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0001570--P:vasculogenesis
KEGG mcc:699545
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002360 Ailuropoda melanoleuca 86.02 0.00e+00 2744.00
IUUC-Bta-013285 Bos taurus 84.10 0.00e+00 2745.00
IUUC-Cja-019033 Callithrix jacchus 91.22 0.00e+00 2926.00
IUUC-Cfa-020695 Canis familiaris 85.36 0.00e+00 1736.00
IUUC-Cpo-021513 Cavia porcellus 78.70 0.00e+00 2470.00
IUUC-Csa-023798 Chlorocebus sabaeus 98.94 0.00e+00 3128.00
IUUC-Dno-029587 Dasypus novemcinctus 81.04 0.00e+00 1474.00
IUUC-Dor-030234 Dipodomys ordii 83.30 0.00e+00 2756.00
IUUC-Ete-032612 Echinops telfairi 76.73 0.00e+00 896.00
IUUC-Eca-033408 Equus caballus 88.31 0.00e+00 2759.00
IUUC-Fca-035483 Felis catus 85.85 0.00e+00 2754.00
IUUC-Gac-041628 Gasterosteus aculeatus 46.53 0.00e+00 1330.00
IUUC-Ggo-044721 Gorilla gorilla 97.00 0.00e+00 3020.00
IUUC-Hsa-046406 Homo sapiens 97.11 0.00e+00 3068.00
IUUC-Itr-048525 Ictidomys tridecemlineatus 86.81 0.00e+00 2732.00
IUUC-Lch-049956 Latimeria chalumnae 44.09 0.00e+00 1067.00
IUUC-Laf-054068 Loxodonta africana 84.68 0.00e+00 2752.00
IUUC-Meu-056198 Macropus eugenii 55.87 0.00e+00 1586.00
IUUC-Mmr-061464 Microcebus murinus 88.18 0.00e+00 2771.00
IUUC-Mdo-062018 Monodelphis domestica 59.55 0.00e+00 1395.00
IUUC-Mmu-063413 Mus musculus 76.84 0.00e+00 2377.00
IUUC-Mpu-066146 Mustela putorius furo 86.98 0.00e+00 2674.00
IUUC-Mlu-067036 Myotis lucifugus 84.66 0.00e+00 2748.00
IUUC-Opr-070670 Ochotona princeps 77.68 0.00e+00 2452.00
IUUC-Oan-073451 Ornithorhynchus anatinus 51.07 0.00e+00 1164.00
IUUC-Ocu-074155 Oryctolagus cuniculus 84.81 0.00e+00 2667.00
IUUC-Oga-089084 Otolemur garnettii 88.16 0.00e+00 2869.00
IUUC-Oar-090029 Ovis aries 85.82 0.00e+00 2756.00
IUUC-Ptr-091282 Pan troglodytes 95.49 0.00e+00 3056.00
IUUC-Pan-091883 Papio anubis 99.41 0.00e+00 3151.00
IUUC-Pab-098383 Pongo abelii 93.29 0.00e+00 2977.00
IUUC-Pca-100519 Procavia capensis 76.03 0.00e+00 838.00
IUUC-Pva-102417 Pteropus vampyrus 84.51 0.00e+00 2239.00
IUUC-Rno-105962 Rattus norvegicus 79.18 0.00e+00 2498.00
IUUC-Sar-113750 Sorex araneus 81.27 4.00e-173 603.00
IUUC-Ssc-115899 Sus scrofa 80.22 0.00e+00 2425.00
IUUC-Tsy-118860 Tarsius syrichta 84.87 0.00e+00 1134.00
IUUC-Tbe-127660 Tupaia belangeri 86.46 0.00e+00 1436.00
Created Date 25-Jun-2017

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