iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-131888

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AAMC01063467

Gene Name

dcun1d1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000016813.3	ENSXETT00000036651.3	ENSXETP00000036651.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	2.10e-90	302.0	61	247
UBD/Alpha-Helix/UBA	3.80e-07	30.2	7	45

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++kkle+l++rYkdp ++ +igi+g+++fc+dl++dp++++vL++awk++aat+cefs++ef+dg+t+lgcdsiekl+++l+++e+elk
   Q: 61   DRKKLEQLYNRYKDPLDEnKIGIDGIQQFCDDLALDPASVSVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQLPKMEQELK 149
           78*************9888********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           +  +fkd+Y+f+fnfak++gqk+ldl++aia+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+fs++ia+d+snYdeegaWP
   Q: 150  EPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLSGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 237
           ***************************************9.************************************************ PP
   S: 179  vliDefveyl 188
           vliD+fve++
   Q: 238  VLIDDFVEFA 247
           ********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q++  +  ++++a+ +L ++++ l++A+++++
   Q: 7    SQKDKVRQFMIfTQSSEKTAVSCLSQNDWKLDVATDNFF 45
           699********9999999*******************99 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

QNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL 60
DRKKLEQLYN RYKDPLDENK IGIDGIQQFC DDLALDPASV SVLIIAWKFR AATQCEFSKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAACAAGT TGAAATCCTC GCAGAAAGAT AAAGTTCGTC AGTTTATGAT TTTCACACAA 60
TCAAGTGAAA AGACTGCCGT GAGTTGCCTG TCCCAGAATG ACTGGAAGCT AGATGTTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	43.90	7.00e-61	226.00
IUUC-Aml-001879	Ailuropoda melanoleuca	98.06	5.00e-151	526.00
IUUC-Atr-002662	Amborella trichopoda	38.69	1.00e-25	109.00
IUUC-Apl-003451	Anas platyrhynchos	96.17	2.00e-148	517.00
IUUC-Aca-005269	Anolis carolinensis	95.74	7.00e-148	516.00
IUUC-Aly-006285	Arabidopsis lyrata	37.40	2.00e-44	171.00
IUUC-Ath-007531	Arabidopsis thaliana	43.90	2.00e-58	218.00
IUUC-Ago-007806	Ashbya gossypii	23.74	1.00e-19	89.70
IUUC-Acl-008172	Aspergillus clavatus	27.00	1.00e-22	100.00
IUUC-Afl-008569	Aspergillus flavus	29.76	2.00e-29	122.00
IUUC-Ani-009241	Aspergillus nidulans	27.05	5.00e-25	107.00
IUUC-Ang-009664	Aspergillus niger	28.00	5.00e-24	104.00
IUUC-Ate-010414	Aspergillus terreus	29.84	2.00e-30	125.00
IUUC-Ame-011763	Astyanax mexicanus	88.76	1.00e-136	478.00
IUUC-Bgr-011991	Blumeria graminis	30.37	7.00e-25	107.00
IUUC-Bta-013561	Bos taurus	97.95	6.00e-143	499.00
IUUC-Bci-013824	Botrytis cinerea	32.28	9.00e-30	123.00
IUUC-Bdi-014138	Brachypodium distachyon	44.31	3.00e-61	228.00
IUUC-Bol-016110	Brassica oleracea	43.09	2.00e-57	214.00
IUUC-Bra-017111	Brassica rapa	43.09	4.00e-57	214.00
IUUC-Cel-018441	Caenorhabditis elegans	36.13	2.00e-50	192.00
IUUC-Cja-019502	Callithrix jacchus	98.06	6.00e-151	526.00
IUUC-Cfa-020523	Canis familiaris	98.36	2.00e-143	501.00
IUUC-Cpo-022196	Cavia porcellus	97.29	6.00e-150	522.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	36.50	4.00e-50	191.00
IUUC-Csa-023551	Chlorocebus sabaeus	98.45	2.00e-151	527.00
IUUC-Cho-024373	Choloepus hoffmanni	96.51	3.00e-144	503.00
IUUC-Cin-025269	Ciona intestinalis	62.26	9.00e-101	359.00
IUUC-Cne-026950	Cryptococcus neoformans	31.60	3.00e-30	125.00
IUUC-Dre-028247	Danio rerio	88.37	1.00e-136	478.00
IUUC-Dno-028974	Dasypus novemcinctus	98.45	2.00e-151	527.00
IUUC-Dor-030696	Dipodomys ordii	87.98	3.00e-131	460.00
IUUC-Dse-031365	Dothistroma septosporum	26.64	2.00e-24	105.00
IUUC-Dme-032197	Drosophila melanogaster	64.52	7.00e-93	333.00
IUUC-Ete-032371	Echinops telfairi	98.06	6.00e-151	526.00
IUUC-Eca-033242	Equus caballus	98.45	2.00e-151	527.00
IUUC-Eeu-035317	Erinaceus europaeus	98.84	1.00e-151	528.00
IUUC-Fca-036061	Felis catus	98.45	2.00e-151	527.00
IUUC-Fal-037372	Ficedula albicollis	96.17	2.00e-148	517.00
IUUC-Fso-038150	Fusarium solani	29.41	2.00e-20	92.80
IUUC-Gmo-038885	Gadus morhua	88.76	1.00e-136	478.00
IUUC-Gga-040935	Gallus gallus	97.29	2.00e-150	523.00
IUUC-Gac-041937	Gasterosteus aculeatus	87.98	2.00e-135	474.00
IUUC-Gma-043545	Glycine max	41.87	8.00e-58	216.00
IUUC-Ggo-044468	Gorilla gorilla	97.31	4.00e-149	520.00
IUUC-Hsa-046089	Homo sapiens	98.45	2.00e-151	527.00
IUUC-Hvu-047636	Hordeum vulgare	39.84	7.00e-23	99.80
IUUC-Itr-047902	Ictidomys tridecemlineatus	75.39	5.00e-120	422.00
IUUC-Kpa-049127	Komagataella pastoris	28.24	3.00e-22	98.20
IUUC-Lch-050600	Latimeria chalumnae	94.57	2.00e-147	513.00
IUUC-Lpe-051540	Leersia perrieri	44.13	4.00e-62	230.00
IUUC-Loc-052509	Lepisosteus oculatus	94.19	2.00e-144	504.00
IUUC-Lma-053103	Leptosphaeria maculans	31.18	5.00e-32	130.00
IUUC-Laf-053527	Loxodonta africana	97.67	8.00e-151	525.00
IUUC-Mcc-055699	Macaca mulatta	88.50	4.00e-145	506.00
IUUC-Meu-056626	Macropus eugenii	77.13	1.00e-110	392.00
IUUC-Mor-056909	Magnaporthe oryzae	29.43	2.00e-25	109.00
IUUC-Mpo-057299	Magnaporthe poae	24.28	3.00e-16	79.00
IUUC-Mtr-057964	Medicago truncatula	41.06	3.00e-57	214.00
IUUC-Mla-058990	Melampsora laricipopulina	28.37	6.00e-19	88.20
IUUC-Mga-059379	Meleagris gallopavo	97.00	2.00e-134	471.00
IUUC-Mvi-060312	Microbotryum violaceum	33.46	4.00e-41	160.00
IUUC-Mmr-060851	Microcebus murinus	98.45	4.00e-151	526.00
IUUC-Mdo-063074	Monodelphis domestica	97.68	7.00e-154	538.00
IUUC-Mmu-063954	Mus musculus	97.67	1.00e-150	524.00
IUUC-Mpu-066870	Mustela putorius furo	98.36	2.00e-143	501.00
IUUC-Mlu-067701	Myotis lucifugus	98.06	1.00e-150	524.00
IUUC-Ncr-068780	Neurospora crassa	26.16	1.00e-23	103.00
IUUC-Nle-069291	Nomascus leucogenys	98.45	2.00e-151	527.00
IUUC-Opr-070265	Ochotona princeps	72.48	1.00e-95	342.00
IUUC-Ont-071408	Oreochromis niloticus	88.80	3.00e-136	477.00
IUUC-Oan-073031	Ornithorhynchus anatinus	98.84	2.00e-151	527.00
IUUC-Ocu-074648	Oryctolagus cuniculus	98.45	2.00e-151	527.00
IUUC-Oba-074993	Oryza barthii	44.31	4.00e-62	230.00
IUUC-Obr-076341	Oryza brachyantha	43.90	2.00e-62	231.00
IUUC-Ogl-077099	Oryza glaberrima	44.31	4.00e-62	230.00
IUUC-Ogu-078285	Oryza glumaepatula	43.90	6.00e-61	226.00
IUUC-Oin-079441	Oryza indica	44.31	5.00e-62	230.00
IUUC-Olo-081037	Oryza longistaminata	44.31	5.00e-62	230.00
IUUC-Ome-081357	Oryza meridionalis	44.31	5.00e-62	230.00
IUUC-Oni-082632	Oryza nivara	43.90	4.00e-62	230.00
IUUC-Opu-083351	Oryza punctata	43.97	6.00e-58	216.00
IUUC-Oru-084306	Oryza rufipogon	44.31	5.00e-62	230.00
IUUC-Osa-085307	Oryza sativa	44.31	5.00e-62	230.00
IUUC-Ola-086371	Oryzias latipes	84.17	3.00e-134	470.00
IUUC-Olu-087646	Ostreococcus lucimarinus	36.29	9.00e-45	173.00
IUUC-Oga-089015	Otolemur garnettii	98.06	5.00e-151	526.00
IUUC-Oar-090405	Ovis aries	98.06	5.00e-151	526.00
IUUC-Ptr-090735	Pan troglodytes	98.45	2.00e-151	527.00
IUUC-Pan-092186	Papio anubis	97.68	4.00e-148	516.00
IUUC-Psi-093110	Pelodiscus sinensis	97.54	1.00e-141	494.00
IUUC-Pno-095145	Phaeosphaeria nodorum	32.54	2.00e-24	105.00
IUUC-Ppa-095306	Physcomitrella patens	43.95	8.00e-59	219.00
IUUC-Pfo-096813	Poecilia formosa	83.85	2.00e-132	464.00
IUUC-Pab-098197	Pongo abelii	78.10	5.00e-118	416.00
IUUC-Pca-100218	Procavia capensis	94.96	5.00e-148	516.00
IUUC-Ppe-102032	Prunus persica	43.15	8.00e-61	226.00
IUUC-Pva-102983	Pteropus vampyrus	93.02	8.00e-138	482.00
IUUC-Pgr-103633	Puccinia graminis	27.87	1.00e-24	106.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	30.56	9.00e-29	120.00
IUUC-Rno-105554	Rattus norvegicus	97.29	9.00e-151	525.00
IUUC-Sce-106358	Saccharomyces cerevisiae	25.00	3.00e-20	91.70
IUUC-Sha-106888	Sarcophilus harrisii	98.06	3.00e-151	527.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.65	3.00e-22	98.20
IUUC-Spo-108207	Schizosaccharomyces pombe	31.94	6.00e-24	103.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	34.11	1.00e-31	129.00
IUUC-Smo-108750	Selaginella moellendorffii	42.28	1.00e-49	189.00
IUUC-Sit-110052	Setaria italica	43.15	4.00e-62	230.00
IUUC-Sly-111489	Solanum lycopersicum	44.94	3.00e-61	228.00
IUUC-Stu-112517	Solanum tuberosum	42.91	3.00e-59	221.00
IUUC-Sar-113509	Sorex araneus	75.19	4.00e-106	377.00
IUUC-Sbi-114113	Sorghum bicolor	43.15	4.00e-62	230.00
IUUC-Sre-115221	Sporisorium reilianum	28.42	2.00e-25	109.00
IUUC-Ssc-115547	Sus scrofa	98.45	2.00e-151	527.00
IUUC-Tgu-117147	Taeniopygia guttata	97.29	4.00e-150	523.00
IUUC-Tru-117740	Takifugu rubripes	86.87	3.00e-134	470.00
IUUC-Tsy-119599	Tarsius syrichta	98.06	5.00e-151	526.00
IUUC-Tni-120315	Tetraodon nigroviridis	81.64	5.00e-130	456.00
IUUC-Tca-121033	Theobroma cacao	43.09	8.00e-59	219.00
IUUC-Tvi-122607	Trichoderma virens	28.95	2.00e-25	109.00
IUUC-Tae-125740	Triticum aestivum	37.63	7.00e-55	206.00
IUUC-Tur-126375	Triticum urartu	35.22	4.00e-52	198.00
IUUC-Tme-126878	Tuber melanosporum	33.60	8.00e-39	154.00
IUUC-Ttr-129086	Tursiops truncatus	87.98	3.00e-131	460.00
IUUC-Uma-129364	Ustilago maydis	30.36	3.00e-34	138.00
IUUC-Vpa-130048	Vicugna pacos	86.05	1.00e-126	445.00
IUUC-Vvi-130834	Vitis vinifera	43.50	2.00e-59	222.00
IUUC-Xma-133580	Xiphophorus maculatus	84.11	2.00e-133	468.00
IUUC-Yli-134595	Yarrowia lipolytica	32.51	2.00e-36	145.00
IUUC-Zma-135642	Zea mays	44.08	7.00e-62	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence