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Tag Content
UUCD2 ID IUUC-Dre-027788
UUCD1 version UUC-DaR-00474
Ensembl Protein ID ENSDARP00000141042.1
UniProt Accession E7FDI3; E7FDI3_DANRE
Genbank Protein ID ENSDARP00000141042
Protein Name Uncharacterized protein
Genbank Nucleotide ID CABZ01074330
Gene Name AREL1; arel1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000100359.1 ENSDART00000170306.1 ENSDARP00000141042.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 2.00e-100 337.4 682 1019
Active Site
Position(s) Description Evidence
987 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.lysendketlqpnpdsglknpehlklFeflGrllgkalqdg... 85
           sd++k++ev f++Ee+ld+gG+ re+++l++k+l++++++lf ++s+n++  ++pn ++   ++ + k++ef+Gr++gk+l+++   
   Q: 682  SDWSKNFEVVFQDEEALDWGGPRREWFELVCKALFDTNNQLFtRFSDNNQGLVHPNAERP--PHLRVKMYEFAGRVVGKCLYESalg 766
           7999**************************************778888999999999998..459******************9999 PP
   S: 86   ....rlldlplsksfyklllgkklsledleevdpelyks.lkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
               +l+++++++sf+ +++g +++++ +e+ d+e+yk+ + +i++n   d++e++l ++ ++ +++    k++eL+pgG++i Vtn
   Q: 767  gsykQLVRARFTRSFLAQIIGLRMNYKYFETDDEEFYKTkVCFILNN---DVSEMDLLFAEEKYSKSGHLEKVVELIPGGAQIAVTN 850
           9999***********************************99****99...9****99999999999999****************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkket.kykggytedspaiqwFwevl 253
           eNk+ Y +l+++yrl ++++e+ve+f +G+ne++p++ll++F+e+elell+cG+ +i+v+d+k+++    g ++ ++++++wFw v+
   Q: 851  ENKNHYLNLLAQYRLASQVREEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDINVQDFKAHAvIVGGSWHFREKVMKWFWAVV 937
           ******************************************************************445778999************ PP
   S: 254  eefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           ++f++ee +++LqF+Tgss+lP+gGf++l p++ +i    +++ lP+++TCfn+L+LP+Y+s+e+l++ L +Ai+e+ +gF++
   Q: 938  SSFTQEELARLLQFTTGSSQLPPGGFNTLCPSFQIIAA-PTHSTLPTAHTCFNQLCLPTYDSYEELHKLLKLAISEGsEGFGM 1019
           ******************************99555555.******************************************97 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MDRLFLLTFV FCSVSWVFFW EVRWKKGKES QIEEWLQGHG LSEYKYLFED VQTLEELSLC 60
VLSRLEEVVK EKRHWREIIE AHVQLLRDFA FQEWLCSQSL EHYYHTLKTL GCTNLDDLAQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-027788|E3,HECT|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAAGTTTTGC TTACTAATAA ACAATACTAA TATAACGTTA AAGGAGAATA CTCACATCCT 60
CTGGTCCTTC AGACTGATCA TTCTTTTCAT GGTCGCATAT TTTTTCTGTT TCTTCTGTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027788|E3,HECT|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
Interpro

IPR017868--Filamin/ABP280_repeat-like
IPR000569--HECT_dom
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
IPR013761--SAM/pointed
PROSITE

PS50194--FILAMIN_REPEAT
PS50237--HECT
Pfam

PF00630--Filamin
PF00632--HECT
SMART

SM00119--HECTc
Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
KEGG dre:100332031
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001308 Ailuropoda melanoleuca 81.27 0.00e+00 1381.00
IUUC-Apl-004071 Anas platyrhynchos 78.49 0.00e+00 1301.00
IUUC-Aca-005218 Anolis carolinensis 80.53 0.00e+00 1356.00
IUUC-Ame-011871 Astyanax mexicanus 92.55 0.00e+00 1943.00
IUUC-Bta-012978 Bos taurus 80.68 0.00e+00 1375.00
IUUC-Cja-019081 Callithrix jacchus 81.04 0.00e+00 1374.00
IUUC-Cfa-020736 Canis familiaris 78.98 0.00e+00 1298.00
IUUC-Cpo-021581 Cavia porcellus 80.80 0.00e+00 1373.00
IUUC-Csa-024189 Chlorocebus sabaeus 75.74 0.00e+00 720.00
IUUC-Cho-024751 Choloepus hoffmanni 80.07 0.00e+00 1332.00
IUUC-Cin-025773 Ciona intestinalis 42.62 6.00e-150 524.00
IUUC-Csv-026090 Ciona savignyi 41.51 1.00e-178 620.00
IUUC-Dno-030022 Dasypus novemcinctus 80.80 0.00e+00 1367.00
IUUC-Dme-031577 Drosophila melanogaster 44.71 0.00e+00 745.00
IUUC-Ete-032402 Echinops telfairi 79.37 0.00e+00 1317.00
IUUC-Eca-033908 Equus caballus 81.41 0.00e+00 1384.00
IUUC-Eeu-034869 Erinaceus europaeus 86.61 0.00e+00 830.00
IUUC-Fca-036023 Felis catus 81.29 0.00e+00 1381.00
IUUC-Fal-037477 Ficedula albicollis 79.79 0.00e+00 1365.00
IUUC-Gmo-039197 Gadus morhua 91.36 0.00e+00 1553.00
IUUC-Gga-040704 Gallus gallus 78.12 0.00e+00 1355.00
IUUC-Gac-041511 Gasterosteus aculeatus 90.51 0.00e+00 1570.00
IUUC-Ggo-044527 Gorilla gorilla 78.03 0.00e+00 1303.00
IUUC-Hsa-046082 Homo sapiens 81.04 0.00e+00 1375.00
IUUC-Itr-048168 Ictidomys tridecemlineatus 81.53 0.00e+00 1381.00
IUUC-Lch-049772 Latimeria chalumnae 69.31 0.00e+00 1395.00
IUUC-Loc-052541 Lepisosteus oculatus 87.08 0.00e+00 1844.00
IUUC-Laf-053852 Loxodonta africana 81.04 0.00e+00 1367.00
IUUC-Mcc-054759 Macaca mulatta 75.52 0.00e+00 649.00
IUUC-Meu-056247 Macropus eugenii 65.44 0.00e+00 723.00
IUUC-Mga-060161 Meleagris gallopavo 78.40 0.00e+00 1331.00
IUUC-Mmr-061447 Microcebus murinus 81.04 0.00e+00 1378.00
IUUC-Mdo-062110 Monodelphis domestica 78.98 0.00e+00 1333.00
IUUC-Mmu-064349 Mus musculus 80.56 0.00e+00 1373.00
IUUC-Mpu-065824 Mustela putorius furo 81.65 0.00e+00 1377.00
IUUC-Mlu-067729 Myotis lucifugus 81.29 0.00e+00 1357.00
IUUC-Nle-069721 Nomascus leucogenys 81.17 0.00e+00 1366.00
IUUC-Opr-070189 Ochotona princeps 80.66 0.00e+00 1363.00
IUUC-Ont-072122 Oreochromis niloticus 92.21 0.00e+00 1557.00
IUUC-Oan-072700 Ornithorhynchus anatinus 72.52 0.00e+00 1083.00
IUUC-Ocu-074057 Oryctolagus cuniculus 81.04 0.00e+00 1378.00
IUUC-Ola-087492 Oryzias latipes 90.63 0.00e+00 1570.00
IUUC-Oga-088084 Otolemur garnettii 81.29 0.00e+00 1370.00
IUUC-Oar-090354 Ovis aries 80.71 0.00e+00 1356.00
IUUC-Ptr-091456 Pan troglodytes 80.92 0.00e+00 1371.00
IUUC-Pan-092596 Papio anubis 80.10 0.00e+00 1348.00
IUUC-Psi-092942 Pelodiscus sinensis 80.27 0.00e+00 1357.00
IUUC-Pma-094662 Petromyzon marinus 62.46 0.00e+00 780.00
IUUC-Pfo-096838 Poecilia formosa 89.41 0.00e+00 1841.00
IUUC-Pab-097849 Pongo abelii 80.80 0.00e+00 1372.00
IUUC-Pca-100498 Procavia capensis 76.15 0.00e+00 747.00
IUUC-Pva-102599 Pteropus vampyrus 80.80 0.00e+00 1357.00
IUUC-Rno-105776 Rattus norvegicus 81.41 0.00e+00 1377.00
IUUC-Sha-106699 Sarcophilus harrisii 79.22 0.00e+00 1340.00
IUUC-Sar-113621 Sorex araneus 80.20 0.00e+00 1339.00
IUUC-Ssc-115742 Sus scrofa 81.04 0.00e+00 1378.00
IUUC-Tgu-116490 Taeniopygia guttata 80.19 0.00e+00 1355.00
IUUC-Tru-117679 Takifugu rubripes 91.61 0.00e+00 1555.00
IUUC-Tsy-119607 Tarsius syrichta 76.90 0.00e+00 944.00
IUUC-Tni-120376 Tetraodon nigroviridis 86.63 0.00e+00 1442.00
IUUC-Tbe-127348 Tupaia belangeri 56.33 4.00e-152 531.00
IUUC-Ttr-128786 Tursiops truncatus 77.64 0.00e+00 1309.00
IUUC-Vpa-130180 Vicugna pacos 78.50 0.00e+00 1060.00
IUUC-Xtr-132631 Xenopus tropicalis 67.15 0.00e+00 1137.00
Created Date 25-Jun-2017

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