iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117893

UUCD1 version

UUC-TaR-01150

Ensembl Protein ID

ENSTRUP00000047357.1

UniProt Accession

H2VDR2; H2VDR2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000018500.1	ENSTRUT00000047517.1	ENSTRUP00000047357.1
ENSTRUG00000018500.1	ENSTRUT00000047518.1	ENSTRUP00000047358.1
ENSTRUG00000018500.1	ENSTRUT00000047519.1	ENSTRUP00000047359.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-83	281.9	91	788

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkg...............ellkslqklfeelwkskkk... 66
           +Gl+NlgNtCY+NSvLQ+L+ +p lr+ +++     k k k ++e++    +               ell s+++l+ ++ + +++   
   Q: 91   VGLNNLGNTCYLNSVLQVLYYCPGLRDGVKKlhklsKRKAKSQKEEE----KneqtaevtedlppqvELLASFNSLIISIEQLQSGfll 175
           6******************************8776522222222222....02334556666666668888888888888533333455 PP
   S: 67   .........avsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk..............eknkpkeeeeeedkselsde... 129
                    a+ pr++l++l++++++++gy q+DaqE+l+++l  ++e+++               e ++               e   
   Q: 176  npdsfgdelATPPRKILHTLRQLNPMYEGYLQHDAQEVLQCILGYIQEACDTirkeqglnrdeaatEVKH---------------Eden 249
           555566666*****************************************66544555544444332222...............1234 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 250  tvaepksstedenqvgskrksdtevgnakkkpksvdakkseaeeevrnkpvtrskrrsssdvmvstreaedagtkklhkeeeaesdgea 338
           44555566666699999999999****************************************************************** PP
   S: 130  ...........................................................................aeekkkkknkslis 143
                                                                                      ++    + + +l++
   Q: 339  kgdktskrkkktklswlrpsgkqpsifskfrrlgkiscttvklpnkpeqenglgegqrsseeaseerppqnmaalKSAGRCQDGLDLME 427
           **************************************************************99999999988777777777777**** PP
   S: 144  dlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeae 218
           +lFqgql  +++clec++ ++r+e+f+d+s+pv +++ +++               +l++++ +f+++e++ ge+ky+ce+c++++eae
   Q: 428  TLFQGQLVLRTRCLECESFTERREDFQDISVPVLDDSPSSPGdfssvspdpkpelkTLTWAIGQFASAERIVGEDKYFCETCRHYTEAE 516
           **********************************999765559********************************************** PP
   S: 219  kklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn 301
           ++l ++k Pev+++hLkRf     + + +    +k+n+ +++pl+L+l+++ct+p+ +q   + Y+L+av++HsG +++sGHY+ayv+ 
   Q: 517  RSLLFDKTPEVITIHLKRFsanslELDPY-AGLSKVNTPLQTPLSLSLEEWCTQPSAAQ--GQHYRLFAVIMHSGvTIGSGHYTAYVRM 602
           *******************5555555555.4567**********************998..9*************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 603  sdlsdvklrpadgpeseeeeeeskpapakkdelpsyddgevsfnlnrrglslaggktggkklseggvgllggqrslssyqlgtsnahpe 691
           ***************************************************************************************** PP
   S: 302  .......................................................ekgkWllfdDskVtevkeeevleetg......st 329
                                                                   +gkWllfdD +V+  +ee++l+ ++      st
   Q: 692  kaasaegpkrrktislsqnpeaglkkepgvgeeapasscgpagateqraldhllqYEGKWLLFDDCEVRLFQEEDFLRACSpetcssST 780
           ********************999999999999999999999999888888887777999*******************999******** PP
   S: 330  aYvlfYkr 337
           +Y+lfY+r
   Q: 781  PYLLFYRR 788
           ******98 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MPGLQGENVV AALGSPVRRN KLSLKFLQRK ETKRALDFSE SQADEPKAFD SLEPEPRSSP 60
CDQVVPGPSP CPASPGFLLP SEKRETLVPF VGLNNLGNTC YLNSVLQVLY YCPGLRDGVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGGCC TGCAAGGTGA AAATGTGGTG GCGGCTTTGG GGAGCCCCGT TAGACGGAAT 60
AAACTCTCTC TCAAGTTCCT CCAGAGGAAA GAAACCAAAC GGGCTCTAGA TTTCTCCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	46.89	7.00e-179	620.00
IUUC-Apl-004204	Anas platyrhynchos	46.18	3.00e-150	525.00
IUUC-Aca-004637	Anolis carolinensis	46.51	3.00e-168	585.00
IUUC-Ame-011718	Astyanax mexicanus	55.49	0.00e+00	718.00
IUUC-Bta-012552	Bos taurus	46.48	9.00e-178	617.00
IUUC-Cja-019588	Callithrix jacchus	47.45	0.00e+00	627.00
IUUC-Cfa-020211	Canis familiaris	47.09	5.00e-178	617.00
IUUC-Cpo-021551	Cavia porcellus	48.07	3.00e-176	612.00
IUUC-Csa-024186	Chlorocebus sabaeus	47.75	1.00e-180	626.00
IUUC-Cho-024739	Choloepus hoffmanni	41.10	5.00e-80	291.00
IUUC-Dre-028184	Danio rerio	54.47	0.00e+00	714.00
IUUC-Dno-029669	Dasypus novemcinctus	46.23	3.00e-174	605.00
IUUC-Dor-030168	Dipodomys ordii	44.58	3.00e-155	542.00
IUUC-Dme-031732	Drosophila melanogaster	33.69	8.00e-23	102.00
IUUC-Ete-032825	Echinops telfairi	43.82	2.00e-103	370.00
IUUC-Eca-033595	Equus caballus	46.84	1.00e-165	577.00
IUUC-Eeu-034877	Erinaceus europaeus	48.62	1.00e-69	258.00
IUUC-Fca-035381	Felis catus	49.30	2.00e-136	478.00
IUUC-Fal-037592	Ficedula albicollis	48.02	4.00e-166	578.00
IUUC-Gmo-039680	Gadus morhua	57.21	0.00e+00	740.00
IUUC-Gga-041196	Gallus gallus	46.43	3.00e-170	592.00
IUUC-Gac-042292	Gasterosteus aculeatus	62.08	0.00e+00	786.00
IUUC-Ggo-044671	Gorilla gorilla	47.75	2.00e-180	625.00
IUUC-Hsa-047020	Homo sapiens	47.41	2.00e-180	626.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	43.33	5.00e-150	525.00
IUUC-Lch-050543	Latimeria chalumnae	46.18	1.00e-151	530.00
IUUC-Loc-052338	Lepisosteus oculatus	54.67	0.00e+00	740.00
IUUC-Laf-053707	Loxodonta africana	45.65	8.00e-174	603.00
IUUC-Mcc-055885	Macaca mulatta	47.87	0.00e+00	629.00
IUUC-Meu-056573	Macropus eugenii	47.74	9.00e-142	497.00
IUUC-Mga-059346	Meleagris gallopavo	46.37	4.00e-162	565.00
IUUC-Mmr-061612	Microcebus murinus	47.43	6.00e-177	614.00
IUUC-Mdo-062887	Monodelphis domestica	47.46	2.00e-168	586.00
IUUC-Mmu-064044	Mus musculus	46.72	6.00e-175	607.00
IUUC-Mpu-066847	Mustela putorius furo	46.48	2.00e-178	619.00
IUUC-Mlu-067684	Myotis lucifugus	46.96	6.00e-177	614.00
IUUC-Nle-070057	Nomascus leucogenys	47.34	5.00e-180	624.00
IUUC-Opr-070463	Ochotona princeps	44.25	8.00e-150	524.00
IUUC-Ont-071975	Oreochromis niloticus	64.93	0.00e+00	863.00
IUUC-Oan-073062	Ornithorhynchus anatinus	53.10	3.00e-25	107.00
IUUC-Ocu-074840	Oryctolagus cuniculus	47.39	4.00e-176	611.00
IUUC-Ola-087088	Oryzias latipes	60.32	0.00e+00	827.00
IUUC-Oga-088472	Otolemur garnettii	47.62	3.00e-177	615.00
IUUC-Oar-089498	Ovis aries	46.66	2.00e-177	616.00
IUUC-Ptr-091395	Pan troglodytes	47.34	2.00e-180	625.00
IUUC-Pan-092462	Papio anubis	47.87	0.00e+00	629.00
IUUC-Psi-093583	Pelodiscus sinensis	46.35	3.00e-143	502.00
IUUC-Pma-094644	Petromyzon marinus	37.83	7.00e-30	123.00
IUUC-Pfo-096314	Poecilia formosa	62.10	0.00e+00	861.00
IUUC-Pab-098568	Pongo abelii	47.34	3.00e-180	625.00
IUUC-Pca-100948	Procavia capensis	46.27	8.00e-82	298.00
IUUC-Pva-102853	Pteropus vampyrus	46.80	9.00e-176	610.00
IUUC-Rno-105573	Rattus norvegicus	47.29	4.00e-176	611.00
IUUC-Sha-107495	Sarcophilus harrisii	47.94	9.00e-137	480.00
IUUC-Sar-113545	Sorex araneus	40.56	5.00e-129	455.00
IUUC-Ssc-115962	Sus scrofa	47.34	3.00e-178	618.00
IUUC-Tgu-116731	Taeniopygia guttata	47.53	3.00e-164	572.00
IUUC-Tsy-119644	Tarsius syrichta	45.08	2.00e-79	290.00
IUUC-Tni-119819	Tetraodon nigroviridis	76.43	0.00e+00	1030.00
IUUC-Tbe-127272	Tupaia belangeri	43.89	6.00e-146	511.00
IUUC-Ttr-128404	Tursiops truncatus	47.53	1.00e-178	619.00
IUUC-Vpa-130205	Vicugna pacos	47.21	1.00e-175	610.00
IUUC-Xtr-132613	Xenopus tropicalis	46.06	4.00e-169	588.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence