iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093164

Ensembl Protein ID

ENSPSIP00000015774.1

UniProt Accession

K7G663; K7G663_PELSI

Genbank Protein ID

ENSPSIP00000015774

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01061191

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014088.1	ENSPSIT00000015849.1	ENSPSIP00000015774.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	65.48	7.00e-126	447.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MWATCCNWFC LDGQPEEMQQ RPQQGARPQA YSNPGYSSYP SPTASEQNCK ACGVHFENSS 60
RKHICFDCKK NFCTSCSSQP ENSPLLCHLC QRFQATAFQR EELIKMKVKD LRDYLALHEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACTATGTG GGCAACCTGT TGTAACTGGT TTTGTCTGGA TGGACAACCT GAGGAGATGC 60
AGCAGAGGCC GCAGCAGGGT GCCAGACCCC AGGCATATTC CAACCCTGGT TACAGCTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	69.32	7.00e-139	486.00
IUUC-Apl-004124	Anas platyrhynchos	79.83	5.00e-152	530.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	7.00e-09	55.80
IUUC-Ath-006716	Arabidopsis thaliana	43.14	4.00e-07	50.10
IUUC-Ame-011616	Astyanax mexicanus	58.79	1.00e-104	372.00
IUUC-Bta-012374	Bos taurus	69.15	9.00e-139	486.00
IUUC-Cja-019780	Callithrix jacchus	68.58	1.00e-144	505.00
IUUC-Cfa-021252	Canis familiaris	70.68	1.00e-139	489.00
IUUC-Cpo-022047	Cavia porcellus	68.49	4.00e-144	503.00
IUUC-Csa-023161	Chlorocebus sabaeus	69.86	8.00e-148	516.00
IUUC-Cho-024316	Choloepus hoffmanni	70.10	2.00e-114	404.00
IUUC-Dre-028596	Danio rerio	55.10	2.00e-106	378.00
IUUC-Dno-029333	Dasypus novemcinctus	69.04	1.00e-144	506.00
IUUC-Ete-033163	Echinops telfairi	70.80	4.00e-135	473.00
IUUC-Eca-033994	Equus caballus	70.41	5.00e-147	513.00
IUUC-Eeu-035162	Erinaceus europaeus	65.44	7.00e-92	329.00
IUUC-Fca-036418	Felis catus	70.96	2.00e-149	521.00
IUUC-Fal-037427	Ficedula albicollis	76.58	3.00e-157	547.00
IUUC-Gga-041053	Gallus gallus	80.94	2.00e-167	581.00
IUUC-Ggo-045436	Gorilla gorilla	70.68	6.00e-150	523.00
IUUC-Hsa-045798	Homo sapiens	70.68	6.00e-150	523.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	69.42	2.00e-143	501.00
IUUC-Lch-050639	Latimeria chalumnae	61.75	2.00e-121	428.00
IUUC-Laf-053355	Loxodonta africana	69.84	3.00e-140	491.00
IUUC-Mcc-055222	Macaca mulatta	69.32	4.00e-143	500.00
IUUC-Meu-056692	Macropus eugenii	69.04	1.00e-142	499.00
IUUC-Mga-059298	Meleagris gallopavo	80.39	4.00e-166	577.00
IUUC-Mmr-061792	Microcebus murinus	69.23	3.00e-143	500.00
IUUC-Mdo-062986	Monodelphis domestica	72.60	2.00e-150	524.00
IUUC-Mmu-063356	Mus musculus	70.96	2.00e-144	504.00
IUUC-Mpu-066273	Mustela putorius furo	71.78	7.00e-152	529.00
IUUC-Mlu-066953	Myotis lucifugus	70.14	8.00e-145	506.00
IUUC-Nle-070075	Nomascus leucogenys	70.96	4.00e-151	527.00
IUUC-Opr-070838	Ochotona princeps	69.04	4.00e-141	493.00
IUUC-Ont-071967	Oreochromis niloticus	49.04	4.00e-90	324.00
IUUC-Ocu-074807	Oryctolagus cuniculus	69.59	2.00e-145	508.00
IUUC-Obr-076159	Oryza brachyantha	42.86	6.00e-09	52.80
IUUC-Ola-086903	Oryzias latipes	69.01	7.00e-52	197.00
IUUC-Oga-088536	Otolemur garnettii	68.13	2.00e-138	484.00
IUUC-Oar-089838	Ovis aries	68.32	9.00e-138	482.00
IUUC-Ptr-090962	Pan troglodytes	70.68	6.00e-150	523.00
IUUC-Pan-092853	Papio anubis	69.32	6.00e-147	513.00
IUUC-Pma-094104	Petromyzon marinus	44.63	1.00e-56	213.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	1.00e-08	56.60
IUUC-Pab-098304	Pongo abelii	70.41	3.00e-149	520.00
IUUC-Pca-100316	Procavia capensis	69.86	1.00e-139	489.00
IUUC-Ppe-101490	Prunus persica	45.10	5.00e-09	55.50
IUUC-Pva-102612	Pteropus vampyrus	59.18	4.00e-111	394.00
IUUC-Rno-105449	Rattus norvegicus	70.68	6.00e-144	503.00
IUUC-Sha-107578	Sarcophilus harrisii	72.33	3.00e-141	494.00
IUUC-Sit-110649	Setaria italica	41.51	2.00e-08	51.20
IUUC-Sar-113638	Sorex araneus	67.67	7.00e-138	483.00
IUUC-Ssc-116401	Sus scrofa	70.96	4.00e-151	526.00
IUUC-Tru-118765	Takifugu rubripes	47.27	2.00e-79	288.00
IUUC-Tsy-118850	Tarsius syrichta	66.78	1.00e-111	395.00
IUUC-Tbe-128086	Tupaia belangeri	65.21	9.00e-134	469.00
IUUC-Vpa-130816	Vicugna pacos	74.42	5.00e-32	130.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence