iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055259

Ensembl Protein ID

ENSMMUP00000031169.3

UniProt Accession

F7GY01; H9Z0M3; F7GY01_MACMU

Genbank Protein ID

AFH29489.1

Protein Name

Mediator of RNA polymerase II transcription subunit 8 isoform 3

Genbank Nucleotide ID

JSUE03001240

Gene Name

MED8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000023671.3	ENSMMUT00000033305.3	ENSMMUP00000031169.3
ENSMMUG00000023671.3	ENSMMUT00000056170.1	ENSMMUP00000059306.1
ENSMMUG00000023671.3	ENSMMUT00000076308.1	ENSMMUP00000045196.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	98.01	3.00e-150	528.00	IUUC-Hsa-046908

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MQREEKQLEA SLDALLSQVA DLKNSLGSFI CKLENEYGRL TWPSVLDSFA LLSGQLNTLN 60
KVLKHEKTPL FRNQVIIPLV LSPDRDEDLM RQTEGRVPVF SHEVVPDHLR TKPDPEVEEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCGAGTT CCAGTTTTCT GATTGGTGGA CGAAGCCCTC TCAGAGGCGT TTGCTGACAG 60
GAAACCGGAA GTGGAAATCG TTGCAGTCGC CTCGGCCGCC GCAATGCAGG TGAGAGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR019364--Mediatior_Med8_fun/met

Pfam

PF10232--Med8

Gene Ontology

GO:0016592--C:mediator complex
GO:0001104--F:RNA polymerase II transcription cofactor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001562	Ailuropoda melanoleuca	96.64	1.00e-129	455.00
IUUC-Apl-004218	Anas platyrhynchos	88.72	1.00e-111	395.00
IUUC-Aca-005363	Anolis carolinensis	86.94	8.00e-123	432.00
IUUC-Ame-011384	Astyanax mexicanus	67.90	1.00e-102	365.00
IUUC-Bta-012751	Bos taurus	96.65	1.00e-128	452.00
IUUC-Cel-018292	Caenorhabditis elegans	26.73	6.00e-19	88.20
IUUC-Cja-019318	Callithrix jacchus	93.69	8.00e-140	489.00
IUUC-Cfa-020106	Canis familiaris	97.30	1.00e-59	223.00
IUUC-Cpo-022416	Cavia porcellus	97.39	2.00e-120	424.00
IUUC-Csa-023695	Chlorocebus sabaeus	99.63	3.00e-133	468.00
IUUC-Cin-025570	Ciona intestinalis	45.31	1.00e-42	166.00
IUUC-Csv-025808	Ciona savignyi	42.86	1.00e-42	166.00
IUUC-Dre-027606	Danio rerio	72.73	1.00e-68	251.00
IUUC-Dno-029924	Dasypus novemcinctus	97.39	2.00e-119	421.00
IUUC-Dor-030115	Dipodomys ordii	94.08	3.00e-131	460.00
IUUC-Dme-031887	Drosophila melanogaster	42.49	5.00e-51	194.00
IUUC-Eca-034101	Equus caballus	98.13	2.00e-131	461.00
IUUC-Eeu-034655	Erinaceus europaeus	88.85	6.00e-122	430.00
IUUC-Fca-036172	Felis catus	96.69	1.00e-130	458.00
IUUC-Fal-036877	Ficedula albicollis	88.01	3.00e-113	400.00
IUUC-Gmo-039244	Gadus morhua	64.21	1.00e-88	318.00
IUUC-Gga-040751	Gallus gallus	88.81	1.00e-112	399.00
IUUC-Gac-041885	Gasterosteus aculeatus	68.27	3.00e-95	341.00
IUUC-Ggo-045201	Gorilla gorilla	98.01	1.00e-149	521.00
IUUC-Hsa-046908	Homo sapiens	98.01	1.00e-149	521.00
IUUC-Itr-048814	Ictidomys tridecemlineatus	98.13	9.00e-132	462.00
IUUC-Lch-049994	Latimeria chalumnae	73.89	9.00e-66	243.00
IUUC-Loc-051765	Lepisosteus oculatus	71.75	1.00e-103	369.00
IUUC-Laf-053336	Loxodonta africana	95.52	1.00e-128	452.00
IUUC-Meu-056166	Macropus eugenii	87.97	5.00e-108	383.00
IUUC-Mga-059317	Meleagris gallopavo	87.97	7.00e-111	393.00
IUUC-Mmr-061501	Microcebus murinus	91.36	1.00e-133	469.00
IUUC-Mdo-062026	Monodelphis domestica	91.45	2.00e-119	421.00
IUUC-Mmu-063469	Mus musculus	97.01	8.00e-129	452.00
IUUC-Mpu-065945	Mustela putorius furo	97.39	3.00e-130	457.00
IUUC-Mlu-067414	Myotis lucifugus	95.52	1.00e-126	445.00
IUUC-Nle-069411	Nomascus leucogenys	98.01	2.00e-150	524.00
IUUC-Opr-070733	Ochotona princeps	94.83	9.00e-126	442.00
IUUC-Ont-071344	Oreochromis niloticus	68.27	2.00e-95	342.00
IUUC-Oan-073366	Ornithorhynchus anatinus	84.13	9.00e-102	362.00
IUUC-Ocu-074762	Oryctolagus cuniculus	96.70	1.00e-124	438.00
IUUC-Ola-086874	Oryzias latipes	66.79	2.00e-91	328.00
IUUC-Oga-088187	Otolemur garnettii	97.00	1.00e-128	452.00
IUUC-Oar-089832	Ovis aries	96.64	7.00e-129	452.00
IUUC-Ptr-091178	Pan troglodytes	97.01	2.00e-147	514.00
IUUC-Pan-092520	Papio anubis	100.00	1.00e-134	471.00
IUUC-Psi-093517	Pelodiscus sinensis	86.47	9.00e-116	409.00
IUUC-Pma-094752	Petromyzon marinus	58.97	5.00e-79	287.00
IUUC-Pfo-096659	Poecilia formosa	68.63	6.00e-91	327.00
IUUC-Pca-101064	Procavia capensis	84.72	7.00e-118	416.00
IUUC-Pva-102173	Pteropus vampyrus	90.70	5.00e-133	466.00
IUUC-Spo-108036	Schizosaccharomyces pombe	28.81	8.00e-04	37.00
IUUC-Sar-113363	Sorex araneus	95.13	3.00e-126	444.00
IUUC-Ssc-115563	Sus scrofa	95.00	6.00e-144	503.00
IUUC-Tgu-116686	Taeniopygia guttata	87.97	4.00e-113	400.00
IUUC-Tru-118003	Takifugu rubripes	66.79	4.00e-89	320.00
IUUC-Tsy-118875	Tarsius syrichta	82.72	7.00e-121	426.00
IUUC-Tni-120624	Tetraodon nigroviridis	62.50	8.00e-82	296.00
IUUC-Tca-121018	Theobroma cacao	23.81	2.00e-03	34.30
IUUC-Tbe-127611	Tupaia belangeri	86.18	1.00e-104	372.00
IUUC-Ttr-129198	Tursiops truncatus	94.10	8.00e-147	512.00
IUUC-Vpa-130245	Vicugna pacos	96.92	4.00e-49	187.00
IUUC-Xtr-132397	Xenopus tropicalis	78.36	3.00e-114	404.00
IUUC-Xma-134285	Xiphophorus maculatus	68.63	1.00e-93	336.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence