iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000024628.6	ENSRNOT00000039524.6	ENSRNOP00000035837.6
ENSRNOG00000024628.6	ENSRNOT00000074278.2	ENSRNOP00000065737.2

Annotation

Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-29	99.0	282	311
UBD/Beta-Prp	2.00e-43	149.1	146	502

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDl 30
           H+d++ c af +  +l++Gs+Dg i +W+ 
   Q: 282  HQDDILCAAFlPPQTLATGSYDGEIVLWNN 311
           9*********955889************95 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgh..eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           +h + ++cv +  + ++++++   +t+  w ++tg++++++ g+  +ae+++++++ ++  l+tgs+D+t+kvwd++ g c htl+  +
   Q: 146  SHLKAVSCVLYNSHLKQVISSDVGSTVSFWMIETGQKIKQFAGChgNAEISTMTLDANKTRLLTGSTDGTVKVWDFN-GYCHHTLNVGQ 233
           46667889***999999************************88722567***************************6.66999999777 PP
   S: 95   dsvlslsfsp.sgdklvsGshdrtirv........wdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           d v+ +s     ++++++ ++ r + v        + ++++++     + +d++ + + ++p  + l++Gs+D+ + lW+ +t++  + 
   Q: 234  DGVVEISQILvLKKTILVVGWERAVTVfrphnfnqFFIQSEEWKG-GVRHQDDILCAAFLPP--QTLATGSYDGEIVLWNNNTENAHHV 319
           777777655548899************555555554455555554.4444555555555555..99***************99999999 PP
   S: 175  ltgghtdsvysls.........fdsng.............................................kelvsgsldgtvklwdl 209
           l  g +++  s+              +                                               lvs++  g+v++wd+
   Q: 320  LHPGYQRQLASMLdleaqklnaG---RsrathcvadqtnqaalnvkidtegnnavmrlcflearktnaatggANLVSCGASGYVRFWDI 405
           94334444444434444444330...03344444444455777777777779999999999999999********************** PP
   S: 210  qtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriW.............dlrsgdllktlqlhnssvisvavlsfg.dnvlvlg 283
            ++  + ++ +h    + v  + + +++l++g  Dg ++iW              +++ +ll++lq h+++++s  + + g +  +++ 
   Q: 406  FKKVLLAEFLAHAGVGSIVMSTdKLNQYLATGDPDGCLKIWnieeyctnstdskVTQTPTLLRSLQPHEDRISSLEMCESGgHLLIISS 494
           ************976664443337799999999********666666654433223344445555555599999999555524444555 PP
   S: 284  sedskvni 291
           s+d++v +
   Q: 495  SADCSVCV 502
           55998865 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

LAWREKSKKL LKMTSFNIAQ GIHAFDYHSR LNLIATAGIN NKVCLWNPYV LSKPVGVLWG 60
HSASVIAVQF FAERKQLFSF SRDKVLRLWD IQHQLSIQRI ACSFPKSQDF RCLFHFDETH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCAAGATC CGAGCCAAAC CATTTGTATG CCCAGAGAAG TATTTGTACA GAAGATGACA 60
GAGACTGTGG GTTGGGGCAC AAAAGAAGAA TATGGAGAAC TCTTTGACAA AGTGGATGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002386	Ailuropoda melanoleuca	78.68	0.00e+00	849.00
IUUC-Aca-005140	Anolis carolinensis	50.77	0.00e+00	666.00
IUUC-Ame-011677	Astyanax mexicanus	55.36	1.00e-114	406.00
IUUC-Bta-013449	Bos taurus	70.82	0.00e+00	1012.00
IUUC-Cja-019381	Callithrix jacchus	72.83	0.00e+00	1035.00
IUUC-Cfa-020449	Canis familiaris	71.45	0.00e+00	1013.00
IUUC-Csa-023219	Chlorocebus sabaeus	67.77	0.00e+00	690.00
IUUC-Cho-024437	Choloepus hoffmanni	90.32	5.00e-116	412.00
IUUC-Cin-025263	Ciona intestinalis	40.43	9.00e-152	531.00
IUUC-Dre-027920	Danio rerio	29.83	2.00e-50	194.00
IUUC-Dno-029512	Dasypus novemcinctus	69.42	0.00e+00	947.00
IUUC-Dor-030182	Dipodomys ordii	79.78	0.00e+00	768.00
IUUC-Ete-033152	Echinops telfairi	68.87	0.00e+00	945.00
IUUC-Eca-033848	Equus caballus	67.63	3.00e-145	507.00
IUUC-Eeu-034535	Erinaceus europaeus	58.22	0.00e+00	696.00
IUUC-Fca-036363	Felis catus	80.43	0.00e+00	866.00
IUUC-Ggo-045225	Gorilla gorilla	74.07	0.00e+00	1062.00
IUUC-Hsa-046739	Homo sapiens	74.22	0.00e+00	1070.00
IUUC-Itr-047862	Ictidomys tridecemlineatus	80.90	0.00e+00	791.00
IUUC-Lch-049722	Latimeria chalumnae	50.07	0.00e+00	691.00
IUUC-Loc-052665	Lepisosteus oculatus	51.42	0.00e+00	694.00
IUUC-Laf-054050	Loxodonta africana	67.64	0.00e+00	837.00
IUUC-Meu-056792	Macropus eugenii	61.70	0.00e+00	629.00
IUUC-Mmr-060714	Microcebus murinus	92.07	1.00e-88	320.00
IUUC-Mdo-062938	Monodelphis domestica	60.43	0.00e+00	847.00
IUUC-Mmu-063645	Mus musculus	84.54	0.00e+00	1208.00
IUUC-Mpu-066015	Mustela putorius furo	71.03	0.00e+00	1024.00
IUUC-Mlu-068140	Myotis lucifugus	71.95	0.00e+00	952.00
IUUC-Nle-069533	Nomascus leucogenys	72.94	0.00e+00	1016.00
IUUC-Opr-070439	Ochotona princeps	56.37	0.00e+00	773.00
IUUC-Ont-072106	Oreochromis niloticus	28.79	2.00e-51	197.00
IUUC-Oan-073559	Ornithorhynchus anatinus	54.23	2.00e-78	285.00
IUUC-Ocu-074202	Oryctolagus cuniculus	89.91	1.00e-116	413.00
IUUC-Oga-087999	Otolemur garnettii	68.46	0.00e+00	724.00
IUUC-Oar-090438	Ovis aries	71.95	0.00e+00	1024.00
IUUC-Ptr-090859	Pan troglodytes	74.07	0.00e+00	1026.00
IUUC-Pan-092049	Papio anubis	80.14	0.00e+00	742.00
IUUC-Psi-093625	Pelodiscus sinensis	56.58	0.00e+00	763.00
IUUC-Pab-098444	Pongo abelii	84.22	0.00e+00	801.00
IUUC-Pca-100464	Procavia capensis	60.53	5.00e-156	545.00
IUUC-Pva-102863	Pteropus vampyrus	71.25	0.00e+00	1019.00
IUUC-Sha-107206	Sarcophilus harrisii	56.98	0.00e+00	768.00
IUUC-Sar-113119	Sorex araneus	56.10	0.00e+00	659.00
IUUC-Ssc-116181	Sus scrofa	80.23	0.00e+00	867.00
IUUC-Tsy-119608	Tarsius syrichta	63.07	0.00e+00	863.00
IUUC-Tni-120461	Tetraodon nigroviridis	42.40	1.00e-25	110.00
IUUC-Tbe-127509	Tupaia belangeri	62.46	0.00e+00	842.00
IUUC-Ttr-128571	Tursiops truncatus	78.89	0.00e+00	724.00
IUUC-Vpa-130340	Vicugna pacos	67.43	0.00e+00	953.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence