iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120401

UUCD1 version

UUC-TeN-01083

Ensembl Protein ID

ENSTNIP00000018069.1

UniProt Accession

H3DC26; H3DC26_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000015018.1	ENSTNIT00000018293.1	ENSTNIP00000018069.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.80e-220	731.8	452	930

Active Site

Position(s)	Description	Evidence
632	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkeln 85
           YD+Qi+++G + qe l +++++lvGag++GcEl Kn++++G+    g++ v+Dmdt+e+snlnrqFLfr++dv k K+++aa a+k++n
   Q: 452  YDGQIAVFGKNVQEMLAKQRYFLVGAGAIGCELMKNFAMIGLaageGEVIVTDMDTIEKSNLNRQFLFRPSDVTKMKSDTAAMAVKQMN 540
           ***************************************************************************************** PP
   S: 86   pdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkti 171
           p  +++ah++++ +++e+i+   Ff+ +d+V +aldn++ar++++r+c+++r+pl+esgtlG++G+v+v+i+ lte+ys+s+dpp+k+i
   Q: 541  PALKITAHQNRVGPDTERIYnddFFESLDGVTNALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSI 629
           ***************************************************************************************** PP
   S: 172  Pfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakt 248
           P+ctlk++pna+eht++wa            + + ++l +++++ e++ kl  +++ e++++v ++l++  + ++++++++a+++++ +
   Q: 630  PICTLKNFPNAIEHTLQWArdefeglfkqppENAMQYL-TDPKFMERTLKLPGAQPVEVLEAVYKSLVTDCPHSWADCVAWARNHWQCQ 717
           *******************************9999999.78888899999*************************************** PP
   S: 249  tinsikqllksfecdivtkskspfwv.......................................................sfcsnaea 282
           ++n+i+qll++f++d++t+s++pfw+                                                               
   Q: 718  YNNNIRQLLHNFPPDQLTSSGAPFWSgpkrcphplefstsnelhmdyvvaaanlfaqtfgvqgstdragvikilqdvkvpvF------- 799
           ***********************************99999999999999999998888888888888877776666555531....... PP
   S: 283  lqvp.....ekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlik 359
                    + +++d+e + ++++     l+ l++ l + e+ + +    ++fekddd   ++d++ aa+nlrae+++i+p  d+++ k
   Q: 800  ---TprsgvKIHVSDQELQNSNSSvddsrLEELKTQLPSPESSQFK-LCAIEFEKDDDTnfHMDFIVAASNLRAENYDIPP-TDRHKSK 883
           ...0233334444444444444334444588888888888777666.559*******************************.******* PP
   S: 360  eiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            iag+iipaiatt+a+v Gl+++E++K+v+g  k e +kn f+++a+
   Q: 884  LIAGKIIPAIATTTAAVVGLVCLELFKIVQGqkKLESYKNGFMNLAL 930
           *******************************888899*****99875 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MSSSPLSKKR RLSGTETKTG SHCSSSNSVK TDLSHTPANG MAKNGSDAEI DEGLYSRQLY 60
VLGHDAMKRM QNSNVLISGM KGLGVEIAKN VILGGVKSVT VHDEGAAEWK DLSSQFYLRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGCT CGCCGCTGTC CAAGAAGCGT CGCTTGTCAG GAACAGAGAC GAAGACGGGA 60
TCCCACTGCT CCTCCTCAAA CTCTGTCAAA ACTGATCTGT CCCACACACC TGCCAACGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0007409--P:axonogenesis
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	46.45	0.00e+00	861.00
IUUC-Aml-001311	Ailuropoda melanoleuca	76.67	0.00e+00	1696.00
IUUC-Atr-002684	Amborella trichopoda	43.80	0.00e+00	863.00
IUUC-Aca-004620	Anolis carolinensis	77.01	0.00e+00	1675.00
IUUC-Aly-005515	Arabidopsis lyrata	44.28	0.00e+00	897.00
IUUC-Ath-006891	Arabidopsis thaliana	44.83	0.00e+00	902.00
IUUC-Ago-007873	Ashbya gossypii	52.81	0.00e+00	1016.00
IUUC-Acl-008181	Aspergillus clavatus	55.57	0.00e+00	1063.00
IUUC-Afl-008455	Aspergillus flavus	53.88	0.00e+00	1016.00
IUUC-Afu-009065	Aspergillus fumigatus	55.27	0.00e+00	1081.00
IUUC-Ani-009371	Aspergillus nidulans	53.86	0.00e+00	1034.00
IUUC-Ang-009737	Aspergillus niger	54.85	0.00e+00	1062.00
IUUC-Aor-010007	Aspergillus oryzae	53.88	0.00e+00	1017.00
IUUC-Ate-010466	Aspergillus terreus	54.02	0.00e+00	1076.00
IUUC-Ame-010933	Astyanax mexicanus	87.52	0.00e+00	1831.00
IUUC-Bgr-012281	Blumeria graminis	53.37	0.00e+00	1055.00
IUUC-Bta-012767	Bos taurus	78.19	0.00e+00	1722.00
IUUC-Bci-013721	Botrytis cinerea	56.07	0.00e+00	1033.00
IUUC-Bdi-014335	Brachypodium distachyon	44.85	0.00e+00	884.00
IUUC-Bol-015665	Brassica oleracea	44.55	0.00e+00	886.00
IUUC-Bra-017522	Brassica rapa	45.55	0.00e+00	870.00
IUUC-Cel-018260	Caenorhabditis elegans	49.02	0.00e+00	964.00
IUUC-Cja-019152	Callithrix jacchus	77.53	0.00e+00	1705.00
IUUC-Cfa-020622	Canis familiaris	76.11	0.00e+00	1642.00
IUUC-Cpo-022526	Cavia porcellus	77.05	0.00e+00	1693.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	45.64	0.00e+00	867.00
IUUC-Csa-023780	Chlorocebus sabaeus	77.81	0.00e+00	1713.00
IUUC-Cin-025790	Ciona intestinalis	63.38	0.00e+00	1334.00
IUUC-Csv-026084	Ciona savignyi	60.45	0.00e+00	1321.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	54.44	0.00e+00	1082.00
IUUC-Cne-026960	Cryptococcus neoformans	57.38	0.00e+00	1113.00
IUUC-Cme-027290	Cyanidioschyzon merolae	45.03	0.00e+00	831.00
IUUC-Dre-028149	Danio rerio	86.58	0.00e+00	1849.00
IUUC-Dno-028884	Dasypus novemcinctus	77.62	0.00e+00	1713.00
IUUC-Dor-030229	Dipodomys ordii	74.41	0.00e+00	1627.00
IUUC-Dse-031524	Dothistroma septosporum	53.55	0.00e+00	1046.00
IUUC-Dme-032045	Drosophila melanogaster	60.16	0.00e+00	1276.00
IUUC-Ete-032544	Echinops telfairi	65.97	0.00e+00	684.00
IUUC-Eca-033330	Equus caballus	77.53	0.00e+00	1715.00
IUUC-Eeu-034717	Erinaceus europaeus	42.49	1.00e-161	563.00
IUUC-Fca-036255	Felis catus	77.81	0.00e+00	1706.00
IUUC-Fal-037445	Ficedula albicollis	46.44	0.00e+00	843.00
IUUC-Fox-038007	Fusarium oxysporum	54.53	2.00e-164	572.00
IUUC-Fso-038339	Fusarium solani	54.83	0.00e+00	1038.00
IUUC-Gmo-039338	Gadus morhua	84.21	0.00e+00	1776.00
IUUC-Ggr-039823	Gaeumannomyces graminis	54.63	0.00e+00	1103.00
IUUC-Gga-040365	Gallus gallus	45.35	0.00e+00	776.00
IUUC-Gac-041773	Gasterosteus aculeatus	88.22	0.00e+00	1865.00
IUUC-Gma-043198	Glycine max	44.37	0.00e+00	862.00
IUUC-Ggo-045336	Gorilla gorilla	77.53	0.00e+00	1698.00
IUUC-Hsa-045982	Homo sapiens	77.34	0.00e+00	1692.00
IUUC-Hvu-047418	Hordeum vulgare	45.83	0.00e+00	878.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	77.71	0.00e+00	1717.00
IUUC-Kpa-049112	Komagataella pastoris	51.27	0.00e+00	997.00
IUUC-Lch-050371	Latimeria chalumnae	81.87	0.00e+00	1784.00
IUUC-Lpe-051299	Leersia perrieri	43.89	0.00e+00	862.00
IUUC-Loc-052936	Lepisosteus oculatus	86.40	0.00e+00	1854.00
IUUC-Lma-053315	Leptosphaeria maculans	54.84	0.00e+00	1098.00
IUUC-Laf-053948	Loxodonta africana	76.11	0.00e+00	1654.00
IUUC-Mcc-055843	Macaca mulatta	77.81	0.00e+00	1715.00
IUUC-Meu-056258	Macropus eugenii	77.15	0.00e+00	1675.00
IUUC-Mor-057269	Magnaporthe oryzae	55.35	0.00e+00	1086.00
IUUC-Mpo-057435	Magnaporthe poae	55.17	0.00e+00	1084.00
IUUC-Mtr-058572	Medicago truncatula	44.95	0.00e+00	848.00
IUUC-Mla-059176	Melampsora laricipopulina	56.26	0.00e+00	1073.00
IUUC-Mvi-060437	Microbotryum violaceum	54.55	0.00e+00	1066.00
IUUC-Mmr-061405	Microcebus murinus	75.45	0.00e+00	1650.00
IUUC-Mdo-062032	Monodelphis domestica	76.03	0.00e+00	1652.00
IUUC-Mmu-063280	Mus musculus	77.15	0.00e+00	1688.00
IUUC-Mac-065505	Musa acuminata	45.72	0.00e+00	879.00
IUUC-Mpu-066409	Mustela putorius furo	77.34	0.00e+00	1712.00
IUUC-Mlu-067217	Myotis lucifugus	77.05	0.00e+00	1693.00
IUUC-Nfi-068407	Neosartorya fischeri	55.08	0.00e+00	1060.00
IUUC-Ncr-068698	Neurospora crassa	55.78	0.00e+00	1097.00
IUUC-Nle-070072	Nomascus leucogenys	74.55	0.00e+00	1588.00
IUUC-Opr-070715	Ochotona princeps	41.54	0.00e+00	740.00
IUUC-Ont-071671	Oreochromis niloticus	91.95	0.00e+00	1950.00
IUUC-Oan-073306	Ornithorhynchus anatinus	46.73	0.00e+00	706.00
IUUC-Ocu-074544	Oryctolagus cuniculus	78.00	0.00e+00	1719.00
IUUC-Oba-075120	Oryza barthii	45.01	0.00e+00	858.00
IUUC-Obr-076557	Oryza brachyantha	45.92	0.00e+00	850.00
IUUC-Ogl-077887	Oryza glaberrima	45.11	0.00e+00	862.00
IUUC-Ogu-078305	Oryza glumaepatula	43.75	0.00e+00	860.00
IUUC-Oin-079370	Oryza indica	44.06	0.00e+00	841.00
IUUC-Olo-081089	Oryza longistaminata	43.65	0.00e+00	858.00
IUUC-Ome-081942	Oryza meridionalis	44.87	0.00e+00	856.00
IUUC-Oni-082365	Oryza nivara	45.06	0.00e+00	860.00
IUUC-Opu-083977	Oryza punctata	44.91	0.00e+00	860.00
IUUC-Oru-084469	Oryza rufipogon	43.75	0.00e+00	862.00
IUUC-Osa-085949	Oryza sativa	45.01	0.00e+00	866.00
IUUC-Ola-087002	Oryzias latipes	88.98	0.00e+00	1903.00
IUUC-Olu-087687	Ostreococcus lucimarinus	45.23	0.00e+00	817.00
IUUC-Oga-088594	Otolemur garnettii	77.17	0.00e+00	1687.00
IUUC-Oar-090068	Ovis aries	77.83	0.00e+00	1714.00
IUUC-Ptr-090581	Pan troglodytes	43.99	0.00e+00	738.00
IUUC-Pan-092114	Papio anubis	77.90	0.00e+00	1718.00
IUUC-Pma-094214	Petromyzon marinus	59.64	3.00e-53	200.00
IUUC-Pno-095154	Phaeosphaeria nodorum	53.92	0.00e+00	1088.00
IUUC-Ppa-095227	Physcomitrella patens	44.85	0.00e+00	870.00
IUUC-Pfo-097184	Poecilia formosa	89.56	0.00e+00	1912.00
IUUC-Pab-097861	Pongo abelii	77.34	0.00e+00	1684.00
IUUC-Pop-098934	Populus trichocarpa	43.62	0.00e+00	891.00
IUUC-Pca-100347	Procavia capensis	74.86	0.00e+00	1353.00
IUUC-Ppe-102012	Prunus persica	44.27	0.00e+00	868.00
IUUC-Pva-102584	Pteropus vampyrus	77.71	0.00e+00	1734.00
IUUC-Pgr-103336	Puccinia graminis	55.22	0.00e+00	1061.00
IUUC-Ptt-103939	Puccinia triticina	54.51	0.00e+00	1053.00
IUUC-Pte-104200	Pyrenophora teres	52.69	0.00e+00	1084.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	52.96	0.00e+00	1078.00
IUUC-Rno-105462	Rattus norvegicus	77.24	0.00e+00	1681.00
IUUC-Sce-106245	Saccharomyces cerevisiae	51.32	0.00e+00	1029.00
IUUC-Sha-107142	Sarcophilus harrisii	77.34	0.00e+00	1690.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	55.40	0.00e+00	1109.00
IUUC-Spo-108034	Schizosaccharomyces pombe	54.39	0.00e+00	1062.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	55.99	0.00e+00	1050.00
IUUC-Smo-109211	Selaginella moellendorffii	45.19	0.00e+00	880.00
IUUC-Sit-110281	Setaria italica	46.09	0.00e+00	885.00
IUUC-Sly-110914	Solanum lycopersicum	44.79	0.00e+00	882.00
IUUC-Stu-112109	Solanum tuberosum	44.50	0.00e+00	882.00
IUUC-Sar-113737	Sorex araneus	77.62	0.00e+00	1705.00
IUUC-Sbi-114089	Sorghum bicolor	45.79	0.00e+00	884.00
IUUC-Sre-115148	Sporisorium reilianum	54.34	0.00e+00	1050.00
IUUC-Ssc-115777	Sus scrofa	77.74	0.00e+00	1712.00
IUUC-Tru-118742	Takifugu rubripes	95.79	0.00e+00	1976.00
IUUC-Tca-121672	Theobroma cacao	45.28	0.00e+00	885.00
IUUC-Tre-122009	Trichoderma reesei	53.18	0.00e+00	1023.00
IUUC-Tvi-122259	Trichoderma virens	54.21	0.00e+00	1021.00
IUUC-Tae-125113	Triticum aestivum	46.45	0.00e+00	861.00
IUUC-Tur-126330	Triticum urartu	46.13	0.00e+00	886.00
IUUC-Tme-127055	Tuber melanosporum	52.79	0.00e+00	972.00
IUUC-Tbe-127487	Tupaia belangeri	73.18	0.00e+00	812.00
IUUC-Ttr-128331	Tursiops truncatus	77.24	0.00e+00	1687.00
IUUC-Uma-129387	Ustilago maydis	54.17	0.00e+00	1041.00
IUUC-Vda-129977	Verticillium dahliae	54.09	0.00e+00	1000.00
IUUC-Vvi-130857	Vitis vinifera	44.23	0.00e+00	870.00
IUUC-Xtr-132026	Xenopus tropicalis	64.11	0.00e+00	1248.00
IUUC-Xma-133805	Xiphophorus maculatus	89.18	0.00e+00	1903.00
IUUC-Yli-134547	Yarrowia lipolytica	53.66	0.00e+00	1081.00
IUUC-Zma-135052	Zea mays	46.04	0.00e+00	889.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence