iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090552

Ensembl Protein ID

ENSPTRP00000018181.5

UniProt Accession

H2QFQ0; H2QFQ0_PANTR

Genbank Protein ID

ENSPTRP00000018181

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03118558

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000010653.5	ENSPTRT00000019648.5	ENSPTRP00000018181.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-18	66.5	628	659
UBD/Beta-Prp	5.20e-42	144.0	762	1003

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           ++v+c++ f  +tl +s+s D t+++W+l +g
   Q: 628  GEVRCVKiFaKGTLAISASKDYTLRLWNLLSG 659
           579***9558669***************9776 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlk.g 92
           ++++ ++v + +++  l+tg+ +g+i + + +   l   l++  ++v+ +  s+d+  l+ ++  r+++++  d + +  ++++  +
   Q: 762  EETPTCAVSV-QKQGKLVTGFSNGSISLVSSKGDRL---LEKLPDAVRFLVVSEDE-SLLAAGFGRLVRIFlaDSRGFRRFMAMDlE 843
           5567777888.666679****************888...56668899********8.7888999********************989 PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGs.lDrtvrlWdlktgkllrtltgg 178
           hed+v +  f  +++ +++Gs d  i+vw l+++  l ++l+g  + v+ ++  +   l++s+s   +  ++Wdl+ +   r     
   Q: 844  HEDMVETAVFGTENNLIITGSLDALIQVWSLSEQGTLLDILEGVGAPVSLLARGG--ALVASASpQSSSFKVWDLSDAHRSRVPAP- 927
           99999999999999***********************99*****99999888777..9999999345689*****55554444433. PP
   S: 179  htdsvyslsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
             d+   +++++ng   ++  ++++++v++wdl +ge  +   + ++ ++++++ ++ ++l +g   g++ ++ l s
   Q: 928  FLDRTGLTAVSHNGsyVYFPKIGDKNKVTIWDLAEGE-EQDSLDTSSEIRCLEVAEQRKLLFTGLVSGVVLVFPLNS 1003
           44455555555555449999****************9.5666678899**************999999999984443 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

VVDLRWGIRN IEATDHLTTE LCLEEVDRCW KTSIGPAFVA LIGDQYGPCL VPSRIDEKEW 60
EVLRDHLTAR PSDLELVARY FQRDENVVPP TYVLQAPGTG EACEPEEATL TSVLRSGVQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCGTTGATC TGAGGTGGGG TATTCGGAAC ATTGAAGCCA CTGACCACTT GACCACAGAA 60
CTCTGCTTGG AGGAGGTTGA CCGGTGTTGG AAAACATCCA TAGGGCCAGC TTTTGTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	80.89	0.00e+00	1071.00
IUUC-Apl-003467	Anas platyrhynchos	58.80	3.00e-82	297.00
IUUC-Ame-011400	Astyanax mexicanus	32.96	2.00e-98	354.00
IUUC-Bta-013223	Bos taurus	81.50	0.00e+00	1062.00
IUUC-Cel-018404	Caenorhabditis elegans	35.18	5.00e-43	171.00
IUUC-Cja-018773	Callithrix jacchus	91.13	0.00e+00	1197.00
IUUC-Cfa-020334	Canis familiaris	82.97	0.00e+00	1060.00
IUUC-Cpo-022316	Cavia porcellus	64.29	0.00e+00	833.00
IUUC-Csa-023631	Chlorocebus sabaeus	94.34	0.00e+00	1238.00
IUUC-Cin-025646	Ciona intestinalis	39.30	1.00e-66	248.00
IUUC-Dre-028241	Danio rerio	32.44	3.00e-93	337.00
IUUC-Dno-029990	Dasypus novemcinctus	76.35	0.00e+00	677.00
IUUC-Dor-030869	Dipodomys ordii	69.71	8.00e-104	371.00
IUUC-Ete-033059	Echinops telfairi	83.98	0.00e+00	854.00
IUUC-Eca-033718	Equus caballus	80.89	0.00e+00	1039.00
IUUC-Fca-035748	Felis catus	79.77	0.00e+00	836.00
IUUC-Gac-041507	Gasterosteus aculeatus	28.02	4.00e-53	203.00
IUUC-Ggo-044551	Gorilla gorilla	93.47	0.00e+00	1219.00
IUUC-Hsa-046787	Homo sapiens	98.17	0.00e+00	1303.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	82.65	0.00e+00	1077.00
IUUC-Lch-049578	Latimeria chalumnae	44.83	2.00e-164	573.00
IUUC-Loc-052039	Lepisosteus oculatus	37.54	2.00e-123	437.00
IUUC-Laf-054240	Loxodonta africana	84.40	0.00e+00	1113.00
IUUC-Mcc-054657	Macaca mulatta	93.27	0.00e+00	1217.00
IUUC-Meu-056591	Macropus eugenii	61.40	6.00e-179	621.00
IUUC-Mmr-061577	Microcebus murinus	78.44	0.00e+00	1028.00
IUUC-Mdo-062895	Monodelphis domestica	63.51	0.00e+00	677.00
IUUC-Mmu-063866	Mus musculus	76.15	0.00e+00	1016.00
IUUC-Mpu-066510	Mustela putorius furo	81.50	0.00e+00	1077.00
IUUC-Mlu-067855	Myotis lucifugus	80.73	0.00e+00	1047.00
IUUC-Nle-069557	Nomascus leucogenys	89.60	0.00e+00	1172.00
IUUC-Opr-071196	Ochotona princeps	61.97	9.00e-101	362.00
IUUC-Ont-072070	Oreochromis niloticus	29.69	7.00e-78	286.00
IUUC-Oan-073437	Ornithorhynchus anatinus	60.31	1.00e-111	397.00
IUUC-Ola-086624	Oryzias latipes	28.07	4.00e-64	240.00
IUUC-Oga-088313	Otolemur garnettii	84.39	0.00e+00	892.00
IUUC-Oar-090123	Ovis aries	81.96	0.00e+00	1077.00
IUUC-Psi-093963	Pelodiscus sinensis	58.53	0.00e+00	686.00
IUUC-Pfo-096197	Poecilia formosa	28.97	7.00e-66	246.00
IUUC-Pab-097755	Pongo abelii	96.34	0.00e+00	1016.00
IUUC-Pca-100809	Procavia capensis	84.39	0.00e+00	878.00
IUUC-Pva-102554	Pteropus vampyrus	84.56	0.00e+00	880.00
IUUC-Rno-105174	Rattus norvegicus	74.16	0.00e+00	960.00
IUUC-Sha-107304	Sarcophilus harrisii	61.62	0.00e+00	824.00
IUUC-Sar-113168	Sorex araneus	71.86	1.00e-120	427.00
IUUC-Tru-118251	Takifugu rubripes	27.43	3.00e-50	194.00
IUUC-Tsy-119276	Tarsius syrichta	76.17	1.00e-117	418.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence