iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033697

UUCD1 version

UUC-EqC-00977

Ensembl Protein ID

ENSECAP00000010530.1

UniProt Accession

F6SA09; F6SA09_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000012273.1	ENSECAT00000013281.1	ENSECAP00000010530.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	7.50e-221	733.7	420	907

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g+itv+D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 420  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtskekGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 508
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ +++ah +++++ +e i+   F+++ d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 509  INPQLKIDAHLNKVCPATEAIYsdeFYTRQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 597
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+k+++ +++eg+++v  +l s++++n++++ie+a+ +f+
   Q: 598  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYPSAEEVLQKIQTGHSLEGCFQV-IKLLSRRPRNWSQCIELARLKFE 685
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d   k++s fw+                                                         +f++
   Q: 686  KYFNHKALQLLHCFPLDTQLKDGSLFWQspkrppspikfdlneplhfsfllnaaklyaavycipfteedlsadallnilsevkiqEFKP 774
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l++++ ++ ++++++++++lsfekddds  ++d++taa+nlra++++iep +d++++k+
   Q: 775  SNKVVQTDETARKPDHVPISSEDernaiFQLEKAISSNEATTSDLQMAVLSFEKDDDSngHIDFITAASNLRAKMYSIEP-ADRFKTKR 862
           ******************999999********************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 863  IAGKIIPAIATSTAAVSGLVALEMIKVAGGyPFEAYKNCFLNLAI 907
           *****************************************9886 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

STNTNLPIMS TESVEIDDAL YSRQRYVLGD TAMQKMAKSR VFLSGMGGLG LEIAKNLVLA 60
GIKALTIHDT EKCQAWDLGI NFFLCEDDVA NMRNRAEAVL QHIAELNPYV HVTTSSVPLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTACAAATA CAAATTTGCC AATCATGTCA ACAGAATCTG TGGAGATTGA TGATGCGTTA 60
TACAGGTAAG GACCTTATGA AAACGGAAAC TTATTTTCCC CATTCATTGT TCTCAAGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	94.36	0.00e+00	2032.00
IUUC-Apl-004158	Anas platyrhynchos	81.25	0.00e+00	1736.00
IUUC-Aca-005349	Anolis carolinensis	79.73	0.00e+00	1759.00
IUUC-Bta-012696	Bos taurus	92.99	0.00e+00	2007.00
IUUC-Cja-019563	Callithrix jacchus	92.71	0.00e+00	1975.00
IUUC-Cfa-020951	Canis familiaris	94.55	0.00e+00	2034.00
IUUC-Cpo-022307	Cavia porcellus	87.84	0.00e+00	1897.00
IUUC-Csa-023647	Chlorocebus sabaeus	92.91	0.00e+00	1982.00
IUUC-Cho-024682	Choloepus hoffmanni	76.23	0.00e+00	923.00
IUUC-Dre-028022	Danio rerio	67.55	0.00e+00	1485.00
IUUC-Dno-029796	Dasypus novemcinctus	90.56	0.00e+00	1941.00
IUUC-Dor-030981	Dipodomys ordii	76.39	0.00e+00	1528.00
IUUC-Ete-032514	Echinops telfairi	77.32	0.00e+00	1136.00
IUUC-Eeu-035323	Erinaceus europaeus	84.86	0.00e+00	1337.00
IUUC-Fca-035858	Felis catus	94.66	0.00e+00	2048.00
IUUC-Fal-036848	Ficedula albicollis	80.41	0.00e+00	1737.00
IUUC-Gmo-039326	Gadus morhua	66.54	0.00e+00	1395.00
IUUC-Gga-040747	Gallus gallus	81.00	0.00e+00	1732.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.09	0.00e+00	1400.00
IUUC-Ggo-044577	Gorilla gorilla	92.62	0.00e+00	1979.00
IUUC-Hsa-046007	Homo sapiens	92.61	0.00e+00	1972.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	95.13	0.00e+00	1070.00
IUUC-Lch-049992	Latimeria chalumnae	73.31	0.00e+00	1546.00
IUUC-Loc-051899	Lepisosteus oculatus	68.88	0.00e+00	1491.00
IUUC-Laf-054413	Loxodonta africana	92.21	0.00e+00	1865.00
IUUC-Mcc-054656	Macaca mulatta	93.20	0.00e+00	1984.00
IUUC-Meu-056463	Macropus eugenii	72.14	0.00e+00	1425.00
IUUC-Mga-059721	Meleagris gallopavo	79.69	0.00e+00	1625.00
IUUC-Mmr-060908	Microcebus murinus	89.50	0.00e+00	1918.00
IUUC-Mdo-062096	Monodelphis domestica	86.10	0.00e+00	1891.00
IUUC-Mmu-064114	Mus musculus	89.17	0.00e+00	1936.00
IUUC-Mpu-066017	Mustela putorius furo	93.59	0.00e+00	2026.00
IUUC-Mlu-068037	Myotis lucifugus	91.50	0.00e+00	1934.00
IUUC-Nle-069494	Nomascus leucogenys	92.42	0.00e+00	1967.00
IUUC-Opr-070910	Ochotona princeps	65.17	1.00e-168	587.00
IUUC-Ont-071592	Oreochromis niloticus	68.13	0.00e+00	1452.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.20	0.00e+00	1594.00
IUUC-Ocu-074296	Oryctolagus cuniculus	93.37	0.00e+00	2012.00
IUUC-Ola-086376	Oryzias latipes	68.85	0.00e+00	1412.00
IUUC-Oga-088186	Otolemur garnettii	91.93	0.00e+00	1962.00
IUUC-Oar-089307	Ovis aries	93.38	0.00e+00	2017.00
IUUC-Ptr-090609	Pan troglodytes	92.91	0.00e+00	1976.00
IUUC-Pan-092905	Papio anubis	92.80	0.00e+00	1887.00
IUUC-Psi-093489	Pelodiscus sinensis	81.35	0.00e+00	1760.00
IUUC-Pma-094203	Petromyzon marinus	66.89	4.00e-58	216.00
IUUC-Pfo-096670	Poecilia formosa	69.37	0.00e+00	1468.00
IUUC-Pab-098418	Pongo abelii	92.91	0.00e+00	1974.00
IUUC-Pca-100889	Procavia capensis	75.88	0.00e+00	1577.00
IUUC-Pva-103144	Pteropus vampyrus	81.73	0.00e+00	1716.00
IUUC-Rno-105612	Rattus norvegicus	89.37	0.00e+00	1935.00
IUUC-Sha-107388	Sarcophilus harrisii	86.91	0.00e+00	1886.00
IUUC-Sar-113128	Sorex araneus	90.07	0.00e+00	1954.00
IUUC-Ssc-116117	Sus scrofa	94.08	0.00e+00	2029.00
IUUC-Tgu-116565	Taeniopygia guttata	80.72	0.00e+00	1751.00
IUUC-Tru-118591	Takifugu rubripes	67.54	0.00e+00	1424.00
IUUC-Tsy-119436	Tarsius syrichta	82.32	0.00e+00	1692.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.83	0.00e+00	1409.00
IUUC-Tbe-127714	Tupaia belangeri	78.97	0.00e+00	1396.00
IUUC-Ttr-129159	Tursiops truncatus	81.54	0.00e+00	1690.00
IUUC-Vpa-130716	Vicugna pacos	90.47	0.00e+00	1898.00
IUUC-Xtr-132947	Xenopus tropicalis	70.34	0.00e+00	1530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence