iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020043

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03004980

Gene Name

UBE2T

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010509.3	ENSCAFT00000016699.3	ENSCAFP00000015455.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.30e-46	157.3	6	145

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rlk+el+ l+++pp+gi++ ++++ ++++++++ilG +dtpYe+gvFkle+++pe+YPf+PP+++flt+i+hPn++++G++Cl++lk  
   Q: 6    RLKRELNLLATEPPPGITCWQDND-QMDDLRAQILGAADTPYEKGVFKLEVTIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKlp 93
           99**********************.7************************************************************998 PP
   S: 88   eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++ +W+p l++++vl+siq l++epnp++pl +++++++k n+  + k++r+
   Q: 94   PKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPVFLKNARQ 145
           99******************************************99999875 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MQRASRLKRE LNLLATEPPP GITCWQDNDQ MDDLRAQILG AADTPYEKGV FKLEVTIPER 60
YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGCGGG GCGACGCCAA CCGCCGTGGC GCGCGCGGTG CGTTGGGAGG CGGGAGGCGG 60
GAGGCGAGGC GCGCAGGTGA GCGGAAGCTG CGTGGGGGCG GCGGCCCTTG AGGCAATCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination

KEGG

cfa:607154

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	56.95	6.00e-45	175.00
IUUC-Aml-001392	Ailuropoda melanoleuca	92.39	6.00e-107	379.00
IUUC-Atr-003069	Amborella trichopoda	45.00	6.00e-51	194.00
IUUC-Apl-003914	Anas platyrhynchos	83.23	8.00e-78	281.00
IUUC-Aca-004381	Anolis carolinensis	70.98	3.00e-79	287.00
IUUC-Aly-006059	Arabidopsis lyrata	54.43	2.00e-47	182.00
IUUC-Ath-007669	Arabidopsis thaliana	59.84	1.00e-44	173.00
IUUC-Ame-011372	Astyanax mexicanus	72.67	6.00e-70	256.00
IUUC-Bta-012479	Bos taurus	83.25	2.00e-93	334.00
IUUC-Bdi-014043	Brachypodium distachyon	49.04	2.00e-53	203.00
IUUC-Bol-016011	Brassica oleracea	52.90	9.00e-45	174.00
IUUC-Bra-017419	Brassica rapa	52.90	3.00e-44	172.00
IUUC-Cja-019773	Callithrix jacchus	87.88	1.00e-98	351.00
IUUC-Cpo-021481	Cavia porcellus	86.80	1.00e-99	355.00
IUUC-Csa-024083	Chlorocebus sabaeus	89.29	2.00e-102	364.00
IUUC-Cho-024386	Choloepus hoffmanni	89.67	9.00e-98	348.00
IUUC-Cin-025419	Ciona intestinalis	64.94	1.00e-62	231.00
IUUC-Csv-026224	Ciona savignyi	66.23	2.00e-63	235.00
IUUC-Cme-027179	Cyanidioschyzon merolae	51.61	4.00e-43	166.00
IUUC-Dre-028800	Danio rerio	75.16	1.00e-72	265.00
IUUC-Dno-029833	Dasypus novemcinctus	87.76	3.00e-101	360.00
IUUC-Ete-032625	Echinops telfairi	86.54	1.00e-73	268.00
IUUC-Eca-033821	Equus caballus	94.81	2.00e-85	307.00
IUUC-Eeu-034578	Erinaceus europaeus	89.05	1.00e-68	251.00
IUUC-Fca-036398	Felis catus	93.40	2.00e-107	381.00
IUUC-Fal-037564	Ficedula albicollis	72.08	5.00e-79	286.00
IUUC-Gmo-039142	Gadus morhua	80.52	1.00e-73	268.00
IUUC-Gga-041054	Gallus gallus	70.83	3.00e-77	280.00
IUUC-Gac-041370	Gasterosteus aculeatus	77.92	2.00e-73	267.00
IUUC-Ggo-045370	Gorilla gorilla	89.34	3.00e-102	363.00
IUUC-Hsa-046513	Homo sapiens	89.85	1.00e-102	365.00
IUUC-Hvu-047694	Hordeum vulgare	56.29	6.00e-50	191.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	82.74	9.00e-96	342.00
IUUC-Lch-050484	Latimeria chalumnae	69.59	2.00e-67	247.00
IUUC-Loc-051967	Lepisosteus oculatus	74.52	5.00e-72	263.00
IUUC-Laf-053377	Loxodonta africana	86.29	8.00e-99	352.00
IUUC-Mcc-055453	Macaca mulatta	89.29	2.00e-102	364.00
IUUC-Meu-056745	Macropus eugenii	79.19	3.00e-90	323.00
IUUC-Mga-059729	Meleagris gallopavo	69.79	3.00e-76	277.00
IUUC-Mmr-060581	Microcebus murinus	89.85	3.00e-104	370.00
IUUC-Mdo-062434	Monodelphis domestica	80.20	3.00e-87	315.00
IUUC-Mmu-064379	Mus musculus	80.20	7.00e-93	332.00
IUUC-Mac-064647	Musa acuminata	56.94	3.00e-47	181.00
IUUC-Mpu-066713	Mustela putorius furo	93.37	6.00e-106	375.00
IUUC-Mlu-067525	Myotis lucifugus	90.91	2.00e-82	296.00
IUUC-Nle-069757	Nomascus leucogenys	90.36	2.00e-103	367.00
IUUC-Opr-070756	Ochotona princeps	80.20	8.00e-93	332.00
IUUC-Ont-071956	Oreochromis niloticus	75.60	6.00e-75	273.00
IUUC-Oan-072745	Ornithorhynchus anatinus	85.99	2.00e-80	290.00
IUUC-Ocu-074423	Oryctolagus cuniculus	83.76	2.00e-94	337.00
IUUC-Oba-075569	Oryza barthii	58.94	8.00e-51	194.00
IUUC-Obr-076131	Oryza brachyantha	58.94	1.00e-50	194.00
IUUC-Ogl-077132	Oryza glaberrima	58.94	8.00e-51	194.00
IUUC-Ogu-078880	Oryza glumaepatula	59.60	3.00e-51	196.00
IUUC-Oin-079748	Oryza indica	59.60	3.00e-51	196.00
IUUC-Olo-080501	Oryza longistaminata	59.60	1.00e-51	197.00
IUUC-Ome-081248	Oryza meridionalis	58.94	1.00e-50	194.00
IUUC-Oni-083033	Oryza nivara	59.60	3.00e-51	196.00
IUUC-Opu-083664	Oryza punctata	59.60	3.00e-51	196.00
IUUC-Oru-084580	Oryza rufipogon	59.60	3.00e-51	196.00
IUUC-Osa-085721	Oryza sativa	59.60	3.00e-51	196.00
IUUC-Ola-087559	Oryzias latipes	75.78	7.00e-73	266.00
IUUC-Oga-088420	Otolemur garnettii	88.38	7.00e-101	359.00
IUUC-Oar-090082	Ovis aries	79.40	6.00e-89	319.00
IUUC-Ptr-091134	Pan troglodytes	89.34	3.00e-102	363.00
IUUC-Pan-091735	Papio anubis	89.29	2.00e-102	364.00
IUUC-Psi-094064	Pelodiscus sinensis	71.14	7.00e-81	292.00
IUUC-Pma-094609	Petromyzon marinus	71.52	2.00e-66	244.00
IUUC-Ppa-095553	Physcomitrella patens	58.28	1.00e-49	191.00
IUUC-Pfo-096710	Poecilia formosa	77.78	3.00e-71	261.00
IUUC-Pab-098126	Pongo abelii	89.85	1.00e-102	365.00
IUUC-Pop-099108	Populus trichocarpa	55.26	1.00e-47	184.00
IUUC-Pca-100338	Procavia capensis	84.77	3.00e-97	347.00
IUUC-Ppe-101239	Prunus persica	57.97	2.00e-44	173.00
IUUC-Pva-102756	Pteropus vampyrus	84.25	2.00e-69	254.00
IUUC-Rno-105211	Rattus norvegicus	76.14	8.00e-86	309.00
IUUC-Sha-106969	Sarcophilus harrisii	73.63	1.00e-79	288.00
IUUC-Smo-109052	Selaginella moellendorffii	55.48	1.00e-45	174.00
IUUC-Sit-110464	Setaria italica	59.18	8.00e-49	188.00
IUUC-Sly-110971	Solanum lycopersicum	60.14	3.00e-48	186.00
IUUC-Stu-112126	Solanum tuberosum	60.81	7.00e-49	188.00
IUUC-Sar-113633	Sorex araneus	82.50	1.00e-92	331.00
IUUC-Sbi-114875	Sorghum bicolor	58.94	3.00e-50	192.00
IUUC-Ssc-116375	Sus scrofa	84.77	2.00e-90	324.00
IUUC-Tgu-117292	Taeniopygia guttata	82.35	2.00e-74	270.00
IUUC-Tru-118157	Takifugu rubripes	66.03	9.00e-59	218.00
IUUC-Tsy-119260	Tarsius syrichta	87.18	6.00e-98	349.00
IUUC-Tni-120162	Tetraodon nigroviridis	62.89	5.00e-73	266.00
IUUC-Tca-121255	Theobroma cacao	55.90	1.00e-37	150.00
IUUC-Tae-123184	Triticum aestivum	56.95	1.00e-44	174.00
IUUC-Tbe-127296	Tupaia belangeri	86.80	5.00e-100	356.00
IUUC-Ttr-128443	Tursiops truncatus	85.93	2.00e-97	347.00
IUUC-Vpa-130689	Vicugna pacos	84.26	2.00e-95	341.00
IUUC-Vvi-130925	Vitis vinifera	57.14	1.00e-47	182.00
IUUC-Xma-133779	Xiphophorus maculatus	72.02	4.00e-72	263.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence