iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071262

Ensembl Protein ID

ENSONIP00000023250.1

UniProt Accession

I3KQ55; I3KQ55_ORENI

Genbank Protein ID

ENSONIP00000023250

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AERX01027520

Gene Name

MARK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000018468.1	ENSONIT00000023270.1	ENSONIP00000023250.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	79.20	0.00e+00	1172.00	IUUC-Hsa-046631

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MSTRTPLPTV NERDTENHSS VDGFVEPQAP PTKSASRHSL PRCRNSFTST EEHPHIGNYR 60
LLKTIGKGNF AKVKLARHVL TGREVAVKII DKTQLNPTSL QKLFREVRIM KILNHPNIVK 120

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Nucleotide Sequence
(Fasta)

GTCTACCTCA ACATGTCTAC GATACTGCGT GATAAAATAC GTCTGTACAG CCACTGTCAG 60
GCTTCGGGGC ATTGTTGAGT AGCAGTGTAG ACCAGTTTGG CAGGCAGCAC ACTCCCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR033627--MARK1
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030010--P:establishment of cell polarity
GO:0000226--P:microtubule cytoskeleton organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001559	Ailuropoda melanoleuca	78.29	0.00e+00	1137.00
IUUC-Ame-011737	Astyanax mexicanus	71.60	0.00e+00	1063.00
IUUC-Bta-013462	Bos taurus	76.82	0.00e+00	1110.00
IUUC-Cja-019358	Callithrix jacchus	78.82	0.00e+00	1200.00
IUUC-Cfa-020498	Canis familiaris	76.76	0.00e+00	1098.00
IUUC-Cpo-022467	Cavia porcellus	76.70	0.00e+00	1135.00
IUUC-Csa-023035	Chlorocebus sabaeus	79.07	0.00e+00	1208.00
IUUC-Dor-031094	Dipodomys ordii	70.30	0.00e+00	972.00
IUUC-Ete-032429	Echinops telfairi	87.53	0.00e+00	723.00
IUUC-Eca-033265	Equus caballus	77.72	0.00e+00	1094.00
IUUC-Fca-035360	Felis catus	75.32	0.00e+00	1068.00
IUUC-Fal-036617	Ficedula albicollis	79.15	0.00e+00	1006.00
IUUC-Gac-041559	Gasterosteus aculeatus	95.24	0.00e+00	1385.00
IUUC-Hsa-046631	Homo sapiens	78.95	0.00e+00	1204.00
IUUC-Laf-054266	Loxodonta africana	77.15	0.00e+00	1132.00
IUUC-Mcc-054650	Macaca mulatta	78.95	0.00e+00	1202.00
IUUC-Mdo-061932	Monodelphis domestica	74.03	0.00e+00	1112.00
IUUC-Mmu-064104	Mus musculus	78.32	0.00e+00	1154.00
IUUC-Mpu-065989	Mustela putorius furo	77.33	0.00e+00	926.00
IUUC-Mlu-067700	Myotis lucifugus	74.97	0.00e+00	1049.00
IUUC-Nle-069385	Nomascus leucogenys	77.74	0.00e+00	1179.00
IUUC-Oan-073352	Ornithorhynchus anatinus	78.54	0.00e+00	1151.00
IUUC-Ocu-073777	Oryctolagus cuniculus	78.07	0.00e+00	1146.00
IUUC-Oar-089313	Ovis aries	74.75	0.00e+00	1097.00
IUUC-Ptr-091421	Pan troglodytes	78.82	0.00e+00	1204.00
IUUC-Psi-093307	Pelodiscus sinensis	80.00	0.00e+00	1131.00
IUUC-Pma-094666	Petromyzon marinus	68.06	0.00e+00	1018.00
IUUC-Pab-098232	Pongo abelii	79.07	0.00e+00	1207.00
IUUC-Pca-100975	Procavia capensis	68.58	0.00e+00	658.00
IUUC-Pva-102596	Pteropus vampyrus	74.84	0.00e+00	1115.00
IUUC-Rno-105027	Rattus norvegicus	77.39	0.00e+00	1136.00
IUUC-Sha-106668	Sarcophilus harrisii	75.50	0.00e+00	1101.00
IUUC-Ssc-115321	Sus scrofa	59.39	0.00e+00	761.00
IUUC-Tgu-116652	Taeniopygia guttata	80.03	0.00e+00	1193.00
IUUC-Tsy-119138	Tarsius syrichta	69.22	0.00e+00	746.00
IUUC-Tni-120412	Tetraodon nigroviridis	95.91	0.00e+00	1412.00
IUUC-Tbe-127841	Tupaia belangeri	77.41	0.00e+00	954.00
IUUC-Ttr-128406	Tursiops truncatus	77.45	0.00e+00	1132.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence