iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000024122.2	ENSPANT00000020162.1	ENSPANP00000014563.1
ENSPANG00000024122.2	ENSPANT00000028725.2	ENSPANP00000014562.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-54	178.1	2100	2132
UBD/Beta-Prp	2.90e-77	259.8	1750	1992

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtg 33
           H d+vt++a+  d+ll+s+s Dg++ +WD+ +g
   Q: 2100 HRDWVTGCAWtKDNLLISCSSDGSVGLWDPESG 2132
           9*********877****************8877 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           ++h+ +it  + spd+++lat +  g++k+wd+ +g+l   +     ++ ++v f+p+g++++tgs  + i  + ++  k +  l +
   Q: 1750 KAHQYQITGCCLSPDRRQLATVCLGGCLKLWDTVRGQL--AFqHTYPKPLNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGA 1834
           678899**9**************************999..332566778************************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
             +sv++l+f+  g ++++G  d+++++w +++g  l  t+  h+g+v  + +   g+ l +++ D++v++W+ + g+   +l +  
   Q: 1835 PGASVRTLAFNVPGGVVAVGRLDSMVELWAWREGARLA-TFPAHHGFVAAALFLHVGCQLLTAGEDGKVQVWSGSLGRPRGDLGSLP 1920
           **************************************.********************************************9989 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
            ++  s++++++g +++ g +   ++++ +++g+   + ++ +  v+ ++ +   + lvsg++Dgs++ W l+
   Q: 1921 LSPALSVALSPDGDRVAVGYRADGIRIYKISSGSQGAQGQALDVAVSALAWL-SPKVLVSGAEDGSLQGWALK 1992
           9********************************9666666666666666666.9****************444 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MEKPHGHVSA HPDILSLENR CLAMLPDLQP MEKLHQHISA HSDILSLKNQ CLATLPDLKT 60
VEKPHGHVSA HPDILSLENR CLATLSDLKT MEKPHGHVSA HPDILSLENR CLATVPSLKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATATACAA ACTGAGTTTC AGCCATGGAA AAACCCCATG GGCATGTGTC TGCCCATCCA 60
GACATCCTCT CCTTGGAGAA CCGGTGCCTG GCTATGCTCC CTGACTTACA GCCCATGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR023302--Pept_S9A_N
IPR027295--Quinoprotein_ADH-like_fam
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	79.41	0.00e+00	3918.00
IUUC-Aca-005102	Anolis carolinensis	42.69	0.00e+00	1656.00
IUUC-Ame-011822	Astyanax mexicanus	34.78	0.00e+00	632.00
IUUC-Bta-012323	Bos taurus	79.83	0.00e+00	3962.00
IUUC-Cja-019005	Callithrix jacchus	92.23	0.00e+00	4798.00
IUUC-Cfa-020803	Canis familiaris	71.98	0.00e+00	3444.00
IUUC-Cpo-022312	Cavia porcellus	74.80	0.00e+00	3543.00
IUUC-Csa-023287	Chlorocebus sabaeus	97.94	0.00e+00	5024.00
IUUC-Dre-028825	Danio rerio	35.48	0.00e+00	1154.00
IUUC-Dno-029455	Dasypus novemcinctus	78.83	0.00e+00	3823.00
IUUC-Dor-030328	Dipodomys ordii	73.83	0.00e+00	2586.00
IUUC-Ete-032385	Echinops telfairi	74.36	0.00e+00	1959.00
IUUC-Eca-033726	Equus caballus	83.15	0.00e+00	4192.00
IUUC-Eeu-034665	Erinaceus europaeus	62.78	0.00e+00	980.00
IUUC-Fca-035365	Felis catus	80.32	0.00e+00	3983.00
IUUC-Gmo-039584	Gadus morhua	32.03	7.00e-124	439.00
IUUC-Gac-042307	Gasterosteus aculeatus	35.94	0.00e+00	1026.00
IUUC-Ggo-045432	Gorilla gorilla	92.25	0.00e+00	4544.00
IUUC-Hsa-046182	Homo sapiens	94.67	0.00e+00	4846.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	80.17	0.00e+00	4041.00
IUUC-Lch-050186	Latimeria chalumnae	39.59	8.00e-79	287.00
IUUC-Laf-054524	Loxodonta africana	79.07	0.00e+00	4002.00
IUUC-Mcc-055628	Macaca mulatta	98.51	0.00e+00	5039.00
IUUC-Meu-056338	Macropus eugenii	63.47	0.00e+00	1302.00
IUUC-Mmr-060854	Microcebus murinus	83.86	0.00e+00	4192.00
IUUC-Mdo-062247	Monodelphis domestica	60.37	0.00e+00	2807.00
IUUC-Mmu-064406	Mus musculus	74.57	0.00e+00	3700.00
IUUC-Mpu-065806	Mustela putorius furo	78.45	0.00e+00	3931.00
IUUC-Mlu-068116	Myotis lucifugus	81.14	0.00e+00	3947.00
IUUC-Nle-069628	Nomascus leucogenys	93.22	0.00e+00	4250.00
IUUC-Opr-070242	Ochotona princeps	79.26	0.00e+00	2879.00
IUUC-Oan-073598	Ornithorhynchus anatinus	52.78	0.00e+00	1935.00
IUUC-Ocu-073933	Oryctolagus cuniculus	80.38	0.00e+00	3952.00
IUUC-Ola-086886	Oryzias latipes	35.27	0.00e+00	1070.00
IUUC-Oga-088609	Otolemur garnettii	81.05	0.00e+00	4002.00
IUUC-Oar-089957	Ovis aries	78.81	0.00e+00	3851.00
IUUC-Ptr-090577	Pan troglodytes	93.15	0.00e+00	4769.00
IUUC-Pma-094373	Petromyzon marinus	35.36	1.00e-76	280.00
IUUC-Pfo-096497	Poecilia formosa	36.16	0.00e+00	1074.00
IUUC-Pab-098028	Pongo abelii	94.56	0.00e+00	4791.00
IUUC-Pca-101002	Procavia capensis	83.43	0.00e+00	1911.00
IUUC-Pva-102144	Pteropus vampyrus	75.08	0.00e+00	1752.00
IUUC-Rno-105828	Rattus norvegicus	74.26	0.00e+00	3750.00
IUUC-Sha-106469	Sarcophilus harrisii	60.42	0.00e+00	2880.00
IUUC-Sar-113035	Sorex araneus	77.57	0.00e+00	1464.00
IUUC-Ssc-116122	Sus scrofa	82.81	0.00e+00	3004.00
IUUC-Tru-118412	Takifugu rubripes	33.00	0.00e+00	1151.00
IUUC-Tsy-119257	Tarsius syrichta	76.66	0.00e+00	1616.00
IUUC-Tni-120032	Tetraodon nigroviridis	33.77	2.00e-40	159.00
IUUC-Tbe-127312	Tupaia belangeri	68.45	0.00e+00	1028.00
IUUC-Ttr-128335	Tursiops truncatus	80.39	0.00e+00	3452.00
IUUC-Xtr-132524	Xenopus tropicalis	39.73	0.00e+00	1403.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence