iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033857

UUCD1 version

UUC-EqC-00024

Ensembl Protein ID

ENSECAP00000015551.1

UniProt Accession

F6PNP6; F6PNP6_HORSE

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018014.1	ENSECAT00000019021.1	ENSECAP00000015551.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.10e-84	283.4	87	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s +kleelf+rYkd++ed+i++eg+e+fc+dl+vdp++++vL+lawk++aat+c+f+r+ef+dg++a+++dsi+++++++++l +e+k+
   Q: 87   SLQKLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQ 175
           679************************************************************************************** PP
   S: 91   eqkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeeg 175
           e+kfkd+Yrf+f+f++d  +gq+sl++++aialwkL+++++++++ld+wl+fL+e+  ++k+is+DtWn++L+f++vi +dlsnY+e++
   Q: 176  EDKFKDLYRFTFQFGLDseEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENpsGIKGISRDTWNMFLNFTQVIGPDLSNYSEDE 264
           ***************998899**********************************9889****************************** PP
   S: 176  aWPvliDefveylk 189
           aWP+l+D+fve+++
   Q: 265  AWPSLFDTFVEWEM 278
           ************85 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRDPSSKSHS RRGAGHREEQ PPACGKPSGD ILVNGTKKAE 60
AATEACQLPT SSGDAGREPK SNAEESSLQK LEELFRRYKD EREDAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTGGTGGA AGAAGAGGCG GAGGCGGCGG GGGTAGGGAG CCTGGAAACG CGAGCGGGGA 60
TGGTAGGTGG TTTGGACCCG CCGGGCCGCC GTCGTTTCCA GAAAGGGTTT GACTGGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0010332--P:response to gamma radiation
GO:0009314--P:response to radiation
GO:0010225--P:response to UV-C

KEGG

ecb:100058079

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	97.37	1.00e-167	582.00
IUUC-Apl-003497	Anas platyrhynchos	82.24	7.00e-143	499.00
IUUC-Aca-004961	Anolis carolinensis	80.92	7.00e-148	516.00
IUUC-Aor-009902	Aspergillus oryzae	33.83	2.00e-11	60.80
IUUC-Ame-011413	Astyanax mexicanus	63.96	6.00e-101	360.00
IUUC-Bta-013338	Bos taurus	96.71	2.00e-166	577.00
IUUC-Cja-019458	Callithrix jacchus	97.04	3.00e-167	580.00
IUUC-Cfa-020160	Canis familiaris	97.70	2.00e-168	584.00
IUUC-Cpo-021835	Cavia porcellus	96.38	3.00e-155	540.00
IUUC-Csa-023328	Chlorocebus sabaeus	97.37	1.00e-167	582.00
IUUC-Cho-024888	Choloepus hoffmanni	95.36	4.00e-165	573.00
IUUC-Cin-025134	Ciona intestinalis	55.32	3.00e-60	225.00
IUUC-Csv-025904	Ciona savignyi	50.41	1.00e-32	130.00
IUUC-Dre-027780	Danio rerio	64.75	2.00e-97	348.00
IUUC-Dno-028866	Dasypus novemcinctus	97.04	8.00e-166	575.00
IUUC-Dor-030387	Dipodomys ordii	95.72	4.00e-164	570.00
IUUC-Dme-032081	Drosophila melanogaster	48.99	3.00e-48	185.00
IUUC-Eeu-034825	Erinaceus europaeus	89.14	1.00e-150	525.00
IUUC-Fca-036130	Felis catus	98.03	2.00e-169	587.00
IUUC-Fal-037296	Ficedula albicollis	81.58	3.00e-141	493.00
IUUC-Gmo-039626	Gadus morhua	64.77	2.00e-98	352.00
IUUC-Ggr-039959	Gaeumannomyces graminis	27.10	2.00e-15	77.80
IUUC-Gga-040741	Gallus gallus	81.58	1.00e-139	488.00
IUUC-Gac-042271	Gasterosteus aculeatus	62.82	1.00e-93	335.00
IUUC-Ggo-044727	Gorilla gorilla	97.37	1.00e-167	582.00
IUUC-Hsa-046288	Homo sapiens	97.04	3.00e-167	580.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	96.71	1.00e-175	608.00
IUUC-Lch-050289	Latimeria chalumnae	79.21	9.00e-134	469.00
IUUC-Loc-052455	Lepisosteus oculatus	71.94	1.00e-108	385.00
IUUC-Laf-054369	Loxodonta africana	96.05	5.00e-159	553.00
IUUC-Mcc-055413	Macaca mulatta	78.57	4.00e-122	430.00
IUUC-Meu-056535	Macropus eugenii	86.84	3.00e-153	533.00
IUUC-Mga-059290	Meleagris gallopavo	82.24	9.00e-142	495.00
IUUC-Mmr-060689	Microcebus murinus	97.04	5.00e-167	579.00
IUUC-Mdo-062128	Monodelphis domestica	86.51	6.00e-147	513.00
IUUC-Mmu-064396	Mus musculus	95.72	4.00e-174	603.00
IUUC-Mpu-065926	Mustela putorius furo	97.37	1.00e-167	582.00
IUUC-Mlu-067044	Myotis lucifugus	95.72	2.00e-174	604.00
IUUC-Nle-069346	Nomascus leucogenys	97.37	1.00e-167	582.00
IUUC-Opr-070682	Ochotona princeps	96.71	5.00e-154	536.00
IUUC-Ont-071772	Oreochromis niloticus	67.74	4.00e-101	360.00
IUUC-Oan-072765	Ornithorhynchus anatinus	84.21	4.00e-146	510.00
IUUC-Ocu-074272	Oryctolagus cuniculus	91.45	3.00e-118	417.00
IUUC-Ola-087561	Oryzias latipes	68.75	2.00e-106	378.00
IUUC-Oga-088440	Otolemur garnettii	77.70	4.00e-123	433.00
IUUC-Oar-089403	Ovis aries	97.37	1.00e-167	582.00
IUUC-Ptr-091384	Pan troglodytes	97.37	1.00e-167	582.00
IUUC-Pan-092650	Papio anubis	97.37	1.00e-167	582.00
IUUC-Psi-093806	Pelodiscus sinensis	83.22	1.00e-135	475.00
IUUC-Pma-094196	Petromyzon marinus	49.54	3.00e-87	314.00
IUUC-Pfo-096584	Poecilia formosa	70.71	1.00e-104	372.00
IUUC-Pab-098605	Pongo abelii	97.37	1.00e-167	582.00
IUUC-Pca-100933	Procavia capensis	79.61	2.00e-116	411.00
IUUC-Pva-102172	Pteropus vampyrus	93.16	2.00e-162	564.00
IUUC-Rno-105406	Rattus norvegicus	96.71	9.00e-176	608.00
IUUC-Sha-106531	Sarcophilus harrisii	85.86	2.00e-152	531.00
IUUC-Sar-113051	Sorex araneus	75.99	7.00e-116	409.00
IUUC-Ssc-115555	Sus scrofa	97.37	8.00e-168	582.00
IUUC-Tgu-117178	Taeniopygia guttata	82.24	4.00e-143	500.00
IUUC-Tru-117876	Takifugu rubripes	68.29	2.00e-106	378.00
IUUC-Tsy-118790	Tarsius syrichta	94.94	2.00e-133	468.00
IUUC-Tni-119673	Tetraodon nigroviridis	65.46	8.00e-106	376.00
IUUC-Tbe-127429	Tupaia belangeri	97.04	3.00e-167	580.00
IUUC-Ttr-128467	Tursiops truncatus	97.70	2.00e-168	584.00
IUUC-Vpa-130376	Vicugna pacos	68.36	2.00e-97	348.00
IUUC-Xtr-132134	Xenopus tropicalis	79.27	1.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence