iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105715

Ensembl Protein ID

ENSRNOP00000021141.7

UniProt Accession

F1M8Z5; F1M8Z5_RAT

Genbank Protein ID

ENSRNOP00000021141

Protein Name

WD repeat domain 27

Genbank Nucleotide ID

AABR07001765

Gene Name

Wdr27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000015609.7	ENSRNOT00000021141.7	ENSRNOP00000021141.7

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-28	96.9	544	575
UBD/Beta-Prp	1.30e-45	156.3	507	815

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH + v+ +++ +d + l+s ++D t++vW++
   Q: 544  GHDGAVNTVCWsHDkRWLLSTARDRTLRVWSV 575
           8**********988899*************97 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..ghedsvls 99
           +tc++fs d+++la g  ++   v+d++   + + +sgh+++v++v++s+d+ +l+++++Drt++vw++   + v+ l   +  + v s
   Q: 507  VTCLQFSGDGQQLACGLGNHLSLVFDASLSGAPAAFSGHDGAVNTVCWSHDKRWLLSTARDRTLRVWSVPRTEFVMLLAadAFPKPVAS 595
           799******************************************************************99999999884466789*** PP
   S: 100  lsfspsgdklvsGshdrtirv........wdletgqclee................tlsghdgvvncvvvhpdg.nllvsGslDrtvrl 163
            +f+  + +++  s  +   +                  +                + +   ++++  +v+++   ++ +++ Drtv +
   Q: 596  AQFYYMDTFILLSSGPEFCLLkyhidlcrD---------DirrykpksrykpifrlPTTSAADITSLSAVNDFYsHIILTAGRDRTVEV 675
           ***996666655555554444435555552.........3334444555777778655555556666666676689************* PP
   S: 164  Wdlktgkllrtltgghtdsvyslsfdsng..........kelvsgsldgtvklwdlqtgecvrtlnght..dnvksvrfspnderlvsg 240
           +dl+ g+    l + h ++v+ +  ++ +          + +++ +    v+lwdl++ +cvr ++gh   + ++ v+fsp ++++++g
   Q: 676  FDLNAGCSAAVLAEVHSRPVHRICQNKGSsfiaqqslayNLFLTTAVGDGVRLWDLRNLRCVRCFEGHPnrSYPCGVAFSPCGKLMACG 764
           ************999********955555566666899999**************************96448899************** PP
   S: 241  ssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniw 292
           ++D+  +++ + s+ +l  l++h ++v+ va+ ++  + l++++ d+k++++
   Q: 765  AEDRHAYVYEMGSSSFLYRLAGHTDTVTEVAF-NPAASQLITATLDGKLQLF 815
           ********************************.**************99987 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPSTGGHMSD IVTERYVVES KQSAAHAPLA CSTQHCAFPL HGNHVCVWSP KDPSHQLLTL 60
QGHHHLITAM VFGNQIDPLL LCSASEDYII MWNMDECREK ALKGLTPRGT VLGSPLQTVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATGGGAGA GCAGAAGAGT TCATTCTGTG CTCACTGCTA CCTTGTCTTT TGGGGGAGCT 60
GGAGTGAGTG GGTAAGCGTG ATGTGTAGCC ATGCTCACAG TGATGAATCA ACTGGACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

KEGG

rno:308222

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	58.42	0.00e+00	790.00
IUUC-Aca-004807	Anolis carolinensis	51.33	0.00e+00	850.00
IUUC-Bta-013316	Bos taurus	60.39	0.00e+00	959.00
IUUC-Cja-018825	Callithrix jacchus	62.31	0.00e+00	1070.00
IUUC-Cfa-020895	Canis familiaris	61.94	0.00e+00	1023.00
IUUC-Cpo-022282	Cavia porcellus	62.02	0.00e+00	999.00
IUUC-Csa-023439	Chlorocebus sabaeus	63.39	0.00e+00	980.00
IUUC-Cho-025046	Choloepus hoffmanni	53.87	0.00e+00	635.00
IUUC-Dre-028376	Danio rerio	41.76	2.00e-167	582.00
IUUC-Dno-029649	Dasypus novemcinctus	60.68	0.00e+00	857.00
IUUC-Dor-030824	Dipodomys ordii	58.42	0.00e+00	733.00
IUUC-Eca-033270	Equus caballus	65.29	0.00e+00	1066.00
IUUC-Fca-036149	Felis catus	59.04	0.00e+00	958.00
IUUC-Fal-037410	Ficedula albicollis	50.36	0.00e+00	678.00
IUUC-Gmo-038923	Gadus morhua	37.44	2.00e-122	432.00
IUUC-Gga-040974	Gallus gallus	48.70	0.00e+00	762.00
IUUC-Gac-042310	Gasterosteus aculeatus	36.14	9.00e-106	377.00
IUUC-Ggo-044557	Gorilla gorilla	63.28	0.00e+00	1069.00
IUUC-Hsa-046312	Homo sapiens	63.27	0.00e+00	1051.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	62.03	0.00e+00	977.00
IUUC-Laf-054450	Loxodonta africana	60.21	0.00e+00	937.00
IUUC-Mcc-055807	Macaca mulatta	58.98	0.00e+00	831.00
IUUC-Meu-056116	Macropus eugenii	34.75	2.00e-60	227.00
IUUC-Mga-060088	Meleagris gallopavo	48.71	0.00e+00	675.00
IUUC-Mdo-062857	Monodelphis domestica	57.14	0.00e+00	960.00
IUUC-Mmu-063220	Mus musculus	87.38	0.00e+00	1227.00
IUUC-Mpu-066921	Mustela putorius furo	58.66	0.00e+00	897.00
IUUC-Mlu-067717	Myotis lucifugus	56.53	0.00e+00	716.00
IUUC-Nle-069061	Nomascus leucogenys	52.00	0.00e+00	801.00
IUUC-Opr-070612	Ochotona princeps	60.85	6.00e-86	312.00
IUUC-Ont-072187	Oreochromis niloticus	39.15	3.00e-159	555.00
IUUC-Oan-072701	Ornithorhynchus anatinus	48.68	1.00e-121	429.00
IUUC-Ocu-074602	Oryctolagus cuniculus	61.37	0.00e+00	994.00
IUUC-Ola-086633	Oryzias latipes	36.87	8.00e-128	451.00
IUUC-Oga-088499	Otolemur garnettii	62.87	0.00e+00	1030.00
IUUC-Oar-089256	Ovis aries	57.53	0.00e+00	907.00
IUUC-Ptr-091545	Pan troglodytes	57.84	0.00e+00	637.00
IUUC-Pan-092299	Papio anubis	63.48	0.00e+00	1063.00
IUUC-Psi-093010	Pelodiscus sinensis	52.32	0.00e+00	853.00
IUUC-Pab-097646	Pongo abelii	54.72	6.00e-170	590.00
IUUC-Pca-100720	Procavia capensis	52.23	9.00e-132	464.00
IUUC-Pva-102808	Pteropus vampyrus	53.41	0.00e+00	793.00
IUUC-Sha-107546	Sarcophilus harrisii	54.93	0.00e+00	931.00
IUUC-Sar-113543	Sorex araneus	48.73	0.00e+00	739.00
IUUC-Ssc-116335	Sus scrofa	69.75	2.00e-46	179.00
IUUC-Tgu-117249	Taeniopygia guttata	48.97	0.00e+00	706.00
IUUC-Tsy-119238	Tarsius syrichta	59.09	0.00e+00	777.00
IUUC-Tni-120639	Tetraodon nigroviridis	34.31	2.00e-52	199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence