iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073881

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02027337

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011180.3	ENSOCUT00000011185.2	ENSOCUP00000009622.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-40	135.6	62	98
UBD/Beta-Prp	3.70e-65	220.1	57	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd..tllvsGsdDgtikvWDlrt 32
           gHt++v+++ f   ++  +l +s+sdDgt+k+WD+ t
   Q: 62   GHTERVSGFTFshhPGqyNLCASSSDDGTVKIWDVET 98
           8************9666799**************976 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +++s+D+t+k+wd++t+  v     h++++ +l++sp  +d +vsG++  ++ ++ l+ +   
   Q: 57   VGELVGHTERVSGFTFSHHPGqynLCASSSDDGTVKIWDVETRAVVTEHALHQHTISALHWSPrVKDLIVSGDEKGVVFCYWLNRNDSQ 145
           68999*************965677***************************************666**************966666666 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............. 192
           +  l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s+            +   +             
   Q: 146  H--LFIEPRAIFCLTCSPHHeDLVAIGYKDGIVVIMDIsKKGEVIHRLRG-HDDEIHSIVwcplpgedclsL---Sqeenseepdihng 228
           5..888888899988888888*****************999********9.*********777777776662...03446788888889 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecvrt 217
                       +l++gs+d+t+++w++++g+ v++
   Q: 229  kvvaqtplskgCYLATGSKDQTIRIWSCSRGRGVMI 264
           99999999999******************9987765 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCSRCS DAVPGGLFGF AARTSVFLVR VGPGAGASPG TPPFRVVGEL 60
VGHTERVSGF TFSHHPGQYN LCASSSDDGT VKIWDVETRA VVTEHALHQH TISALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAGG AACCGCGGAC TCTGCCGCCC TCCCCCAACT GGTACTGCTC CCGCTGCAGC 60
GATGCGGTAC CCGGCGGCCT CTTCGGCTTC GCGGCCCGAA CCTCCGTCTT CCTTGTGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	87.36	0.00e+00	2613.00
IUUC-Apl-003586	Anas platyrhynchos	61.94	0.00e+00	1649.00
IUUC-Aca-004956	Anolis carolinensis	62.77	0.00e+00	1883.00
IUUC-Ame-010753	Astyanax mexicanus	62.66	0.00e+00	1003.00
IUUC-Bta-012315	Bos taurus	86.31	0.00e+00	2613.00
IUUC-Cja-019334	Callithrix jacchus	87.54	0.00e+00	2664.00
IUUC-Cfa-021254	Canis familiaris	86.87	0.00e+00	2660.00
IUUC-Cpo-021984	Cavia porcellus	82.06	0.00e+00	2378.00
IUUC-Csa-023650	Chlorocebus sabaeus	87.96	0.00e+00	2635.00
IUUC-Cho-024860	Choloepus hoffmanni	81.70	0.00e+00	2397.00
IUUC-Cin-025778	Ciona intestinalis	36.07	0.00e+00	669.00
IUUC-Csv-026313	Ciona savignyi	41.11	1.00e-165	576.00
IUUC-Dre-028096	Danio rerio	63.17	0.00e+00	1011.00
IUUC-Dno-029799	Dasypus novemcinctus	88.69	0.00e+00	2247.00
IUUC-Dor-030885	Dipodomys ordii	74.43	0.00e+00	1106.00
IUUC-Ete-032918	Echinops telfairi	80.30	0.00e+00	2409.00
IUUC-Eca-034144	Equus caballus	86.76	0.00e+00	2555.00
IUUC-Eeu-034843	Erinaceus europaeus	78.66	0.00e+00	1818.00
IUUC-Fca-035948	Felis catus	86.91	0.00e+00	2598.00
IUUC-Fal-037303	Ficedula albicollis	61.52	0.00e+00	1828.00
IUUC-Gmo-039591	Gadus morhua	53.57	0.00e+00	849.00
IUUC-Gga-040570	Gallus gallus	62.44	0.00e+00	1677.00
IUUC-Gac-042646	Gasterosteus aculeatus	47.56	0.00e+00	1352.00
IUUC-Ggo-045605	Gorilla gorilla	81.42	0.00e+00	1867.00
IUUC-Hsa-046122	Homo sapiens	88.84	0.00e+00	2657.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	90.03	0.00e+00	2286.00
IUUC-Lch-050489	Latimeria chalumnae	50.43	0.00e+00	872.00
IUUC-Loc-052259	Lepisosteus oculatus	61.35	0.00e+00	978.00
IUUC-Laf-053338	Loxodonta africana	86.34	0.00e+00	2579.00
IUUC-Mcc-055442	Macaca mulatta	88.09	0.00e+00	2635.00
IUUC-Meu-056245	Macropus eugenii	81.52	0.00e+00	858.00
IUUC-Mga-060202	Meleagris gallopavo	62.46	0.00e+00	1722.00
IUUC-Mmr-061730	Microcebus murinus	87.19	0.00e+00	2610.00
IUUC-Mdo-062880	Monodelphis domestica	73.74	0.00e+00	2213.00
IUUC-Mmu-063930	Mus musculus	81.76	0.00e+00	2351.00
IUUC-Mpu-066605	Mustela putorius furo	86.76	0.00e+00	2620.00
IUUC-Mlu-067765	Myotis lucifugus	86.05	0.00e+00	2622.00
IUUC-Nle-069183	Nomascus leucogenys	88.12	0.00e+00	2593.00
IUUC-Opr-070659	Ochotona princeps	82.70	0.00e+00	1266.00
IUUC-Ont-072356	Oreochromis niloticus	62.17	0.00e+00	1009.00
IUUC-Oan-073056	Ornithorhynchus anatinus	70.19	0.00e+00	2016.00
IUUC-Ola-087120	Oryzias latipes	57.49	3.00e-66	244.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.29	1.00e-30	128.00
IUUC-Oga-088343	Otolemur garnettii	88.38	0.00e+00	2663.00
IUUC-Oar-089257	Ovis aries	86.88	0.00e+00	2625.00
IUUC-Ptr-090497	Pan troglodytes	88.58	0.00e+00	2618.00
IUUC-Pan-092638	Papio anubis	87.91	0.00e+00	2622.00
IUUC-Psi-093096	Pelodiscus sinensis	64.52	0.00e+00	1659.00
IUUC-Pma-094571	Petromyzon marinus	43.56	6.00e-88	317.00
IUUC-Pfo-096348	Poecilia formosa	61.87	0.00e+00	975.00
IUUC-Pab-098153	Pongo abelii	88.05	0.00e+00	2656.00
IUUC-Pca-100957	Procavia capensis	79.44	0.00e+00	2393.00
IUUC-Pva-102439	Pteropus vampyrus	87.73	0.00e+00	2670.00
IUUC-Rno-105891	Rattus norvegicus	82.49	0.00e+00	2356.00
IUUC-Sha-107181	Sarcophilus harrisii	74.12	0.00e+00	2114.00
IUUC-Ssc-115413	Sus scrofa	86.70	0.00e+00	2658.00
IUUC-Tgu-117082	Taeniopygia guttata	63.02	0.00e+00	1811.00
IUUC-Tru-118491	Takifugu rubripes	60.84	0.00e+00	962.00
IUUC-Tsy-119629	Tarsius syrichta	92.04	1.00e-165	577.00
IUUC-Tni-120240	Tetraodon nigroviridis	60.55	0.00e+00	960.00
IUUC-Tbe-127673	Tupaia belangeri	76.06	0.00e+00	2123.00
IUUC-Ttr-128562	Tursiops truncatus	83.96	0.00e+00	2543.00
IUUC-Vpa-130596	Vicugna pacos	83.41	0.00e+00	1850.00
IUUC-Xtr-132469	Xenopus tropicalis	55.88	0.00e+00	1624.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence