iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054150

UUCD1 version

UUC-LoA-00068

Ensembl Protein ID

ENSLAFP00000001898.3

UniProt Accession

G3SQ51; G3SQ51_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000002272.3	ENSLAFT00000002272.3	ENSLAFP00000001898.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.10e-08	35.4	16	87
E3 activity/RING/RING	1.80e-06	28.8	20	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
           ee  C+I l+lM dPv +++G++y   +I  ++++ ++         cP +r+p++  ++ Pn+ l +li+a
   Q: 16   EEATCSICLNLMADPVSISCGHSYCHLCIVGFFENIRHmkpqeekfLCPQCRAPFKTASVRPNKQLGSLIEA 87
           6889*****************************8888888999999*********************99987 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl....qkwpglknssskefrCPlCr 46
           C+iCl+ + d p++ +CgH +++ C+    +++  +++ +  +f+CP Cr
   Q: 20   CSICLNLMAD-PVSISCGHSYCHLCIvgffENI-RHMKPQEEKFLCPQCR 67
           **********.**************86666777.77778999999****8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LIKAMASATP AKKMREEATC SICLNLMADP VSISCGHSYC HLCIVGFFEN IRHMKPQEEK 60
FLCPQCRAPF KTASVRPNKQ LGSLIEAIKE MNCEMVCEEH GEQLHLFCED EGQLICWRCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAATAAAAG CCATGGCCTC AGCCACACCT GCAAAAAAGA TGAGGGAGGA AGCCACCTGC 60
TCCATCTGCT TAAACTTGAT GGCTGACCCA GTGAGCATCA GCTGTGGACA CAGCTACTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	74.09	0.00e+00	715.00
IUUC-Aly-006134	Arabidopsis lyrata	38.60	6.00e-07	48.10
IUUC-Ago-007781	Ashbya gossypii	30.34	1.00e-08	53.90
IUUC-Bta-012574	Bos taurus	74.51	0.00e+00	718.00
IUUC-Bci-013692	Botrytis cinerea	43.10	4.00e-08	53.50
IUUC-Cja-019759	Callithrix jacchus	73.98	0.00e+00	675.00
IUUC-Cfa-020431	Canis familiaris	71.61	0.00e+00	684.00
IUUC-Cpo-022541	Cavia porcellus	63.75	1.00e-179	622.00
IUUC-Csa-023320	Chlorocebus sabaeus	73.98	0.00e+00	717.00
IUUC-Cho-024964	Choloepus hoffmanni	74.09	2.00e-136	478.00
IUUC-Dno-029741	Dasypus novemcinctus	69.89	0.00e+00	654.00
IUUC-Dor-030298	Dipodomys ordii	59.66	5.00e-99	353.00
IUUC-Ete-032493	Echinops telfairi	67.74	0.00e+00	637.00
IUUC-Eca-033962	Equus caballus	75.27	0.00e+00	714.00
IUUC-Eeu-035228	Erinaceus europaeus	65.85	3.00e-123	435.00
IUUC-Fca-036349	Felis catus	70.97	0.00e+00	688.00
IUUC-Ggo-044493	Gorilla gorilla	75.21	0.00e+00	738.00
IUUC-Hsa-046161	Homo sapiens	74.19	0.00e+00	727.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	59.96	2.00e-148	518.00
IUUC-Mcc-055076	Macaca mulatta	73.98	0.00e+00	719.00
IUUC-Mmu-063517	Mus musculus	52.68	1.00e-135	476.00
IUUC-Mpu-065752	Mustela putorius furo	72.59	0.00e+00	707.00
IUUC-Mlu-067758	Myotis lucifugus	57.00	5.00e-146	511.00
IUUC-Nle-069117	Nomascus leucogenys	74.78	0.00e+00	724.00
IUUC-Opr-071144	Ochotona princeps	65.38	2.00e-176	611.00
IUUC-Ocu-074825	Oryctolagus cuniculus	67.74	0.00e+00	653.00
IUUC-Oru-085105	Oryza rufipogon	45.16	4.00e-08	52.00
IUUC-Oga-088744	Otolemur garnettii	66.67	5.00e-116	410.00
IUUC-Oar-089951	Ovis aries	73.64	0.00e+00	710.00
IUUC-Ptr-090519	Pan troglodytes	74.62	0.00e+00	728.00
IUUC-Pan-092059	Papio anubis	73.93	0.00e+00	725.00
IUUC-Pab-098747	Pongo abelii	75.91	0.00e+00	739.00
IUUC-Pca-100294	Procavia capensis	80.65	0.00e+00	794.00
IUUC-Pva-102129	Pteropus vampyrus	65.38	0.00e+00	647.00
IUUC-Sar-113760	Sorex araneus	60.00	1.00e-152	533.00
IUUC-Tsy-119422	Tarsius syrichta	69.25	0.00e+00	640.00
IUUC-Tbe-127628	Tupaia belangeri	59.38	3.00e-93	334.00
IUUC-Ttr-129039	Tursiops truncatus	76.56	0.00e+00	736.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence