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Tag Content
UUCD2 ID IUUC-Sha-107071
UUCD1 version UUC-SaH-00432
Ensembl Protein ID ENSSHAP00000010977.1
UniProt Accession G3W6C2; G3W6C2_SARHA
Genbank Protein ID ENSSHAP00000010977
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01222784
Gene Name PRPF19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000009462.1 ENSSHAT00000011071.1 ENSSHAP00000010977.1
ENSSHAG00000009462.1 ENSSHAT00000011072.1 ENSSHAP00000010978.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.80e-15 56.9 3 64
E3 adaptor/Cullin RING/DCX/DWD 5.30e-32 108.6 412 445
UBD/Beta-Prp 5.60e-54 183.5 253 483
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           ++C+Is+e++++P+v+p s+++y+r+ Iek++a++g+ +P+++qpl+ee+l++ ++ + +  +
   Q: 3    LICSISNEVPEHPCVSPvSNHVYERRLIEKYIAENGT-DPINNQPLSEEQLIDIKVAHPIRPK 64
           79**********************************9.***************9998877665 PP
   

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l++++dD ++k+WDlr+
   Q: 412  GHSGPITSIAFseNGYYLATAADDSSVKLWDLRK 445
           8**********976699**************986 PP
   

   UBD/Beta-Prp
   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
             d++ ++tg++d+ + v+d ++++ l++l+gh+++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+ v+ ls++++gd
   Q: 253  PSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 341
           568899*********************************************************************************** PP
   S: 108  klvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
           +l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l
   Q: 342  YLLSSSDDQYWAFSDIQTGRVLTKvTDETSGCALTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYL 429
           **********************997777777799************************************9.***************** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           +++++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 430  ATAADDSSVKLWDLRKLKNFKTLQLDNNfEVKSLIFDQSGTYLALGGTDVQIYI 483
           ***************999999999866527*******************99987 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MSLICSISNE VPEHPCVSPV SNHVYERRLI EKYIAENGTD PINNQPLSEE QLIDIKVAHP 60
IRPKPPSATS IPAILKALQD EWGTGPEAIT PEVPPGSSAT PLPQDAVMLH SFTLRQQLQT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107071|E3,U-box;E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTCCAAACAG TTGGAGTGAC GTCAAGACAC GGCGCGTTTT AACGCCAAGG ACTCCGCCCC 60
GGGGCGTCAA ATCTCGCGGT CTTTCAACCT TTCGTATTCC TCTCGGGAAT CGGACGGCCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107071|E3,U-box;E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00504--Ubox
SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0001833--P:inner cell mass cell proliferation
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000488 Aegilops tauschii 37.50 5.00e-93 336.00
IUUC-Aml-001230 Ailuropoda melanoleuca 91.75 0.00e+00 942.00
IUUC-Atr-002594 Amborella trichopoda 42.29 6.00e-115 407.00
IUUC-Apl-003686 Anas platyrhynchos 88.86 0.00e+00 746.00
IUUC-Aca-005272 Anolis carolinensis 93.35 0.00e+00 988.00
IUUC-Aly-005586 Arabidopsis lyrata 42.30 1.00e-115 410.00
IUUC-Ath-007696 Arabidopsis thaliana 42.38 9.00e-112 397.00
IUUC-Acl-008335 Aspergillus clavatus 34.23 1.00e-64 240.00
IUUC-Afl-008527 Aspergillus flavus 36.09 7.00e-69 254.00
IUUC-Afu-008957 Aspergillus fumigatus 36.62 3.00e-75 275.00
IUUC-Ani-009280 Aspergillus nidulans 35.88 1.00e-62 234.00
IUUC-Ang-009746 Aspergillus niger 34.48 7.00e-63 234.00
IUUC-Aor-009905 Aspergillus oryzae 35.89 1.00e-72 266.00
IUUC-Ate-010412 Aspergillus terreus 36.29 1.00e-61 230.00
IUUC-Ame-011561 Astyanax mexicanus 77.48 4.00e-107 380.00
IUUC-Bgr-012283 Blumeria graminis 31.41 1.00e-52 200.00
IUUC-Bta-013242 Bos taurus 95.25 0.00e+00 999.00
IUUC-Bci-013901 Botrytis cinerea 32.19 6.00e-61 228.00
IUUC-Bdi-014277 Brachypodium distachyon 41.80 1.00e-119 423.00
IUUC-Bol-016207 Brassica oleracea 43.68 7.00e-115 407.00
IUUC-Bra-017902 Brassica rapa 41.74 5.00e-113 401.00
IUUC-Cel-018271 Caenorhabditis elegans 49.62 6.00e-149 520.00
IUUC-Cja-019879 Callithrix jacchus 95.07 0.00e+00 995.00
IUUC-Cfa-020175 Canis familiaris 94.87 0.00e+00 997.00
IUUC-Cpo-022379 Cavia porcellus 94.87 0.00e+00 998.00
IUUC-Cre-022993 Chlamydomonas reinhardtii 38.68 1.00e-95 343.00
IUUC-Csa-023500 Chlorocebus sabaeus 95.44 0.00e+00 1001.00
IUUC-Cho-025065 Choloepus hoffmanni 81.98 3.00e-145 507.00
IUUC-Cin-025699 Ciona intestinalis 65.28 6.00e-173 600.00
IUUC-Csv-026128 Ciona savignyi 62.55 0.00e+00 669.00
IUUC-Cgl-026507 Colletotrichum gloeosporioides 31.45 1.00e-60 227.00
IUUC-Cne-026860 Cryptococcus neoformans 36.89 4.00e-90 325.00
IUUC-Dre-028187 Danio rerio 81.40 0.00e+00 850.00
IUUC-Dno-029453 Dasypus novemcinctus 95.25 0.00e+00 1000.00
IUUC-Dor-030150 Dipodomys ordii 98.74 4.00e-128 451.00
IUUC-Dse-031220 Dothistroma septosporum 31.06 2.00e-54 206.00
IUUC-Dme-031906 Drosophila melanogaster 62.81 0.00e+00 651.00
IUUC-Ete-033035 Echinops telfairi 82.89 0.00e+00 845.00
IUUC-Eca-033478 Equus caballus 95.06 0.00e+00 997.00
IUUC-Eeu-034974 Erinaceus europaeus 99.09 0.00e+00 679.00
IUUC-Fca-036194 Felis catus 94.08 0.00e+00 985.00
IUUC-Fal-037417 Ficedula albicollis 93.16 0.00e+00 984.00
IUUC-Fox-037922 Fusarium oxysporum 32.89 7.00e-61 228.00
IUUC-Fso-038256 Fusarium solani 33.01 3.00e-62 232.00
IUUC-Gmo-038713 Gadus morhua 82.73 0.00e+00 867.00
IUUC-Ggr-039854 Gaeumannomyces graminis 31.12 4.00e-51 195.00
IUUC-Gga-041143 Gallus gallus 93.54 0.00e+00 988.00
IUUC-Gac-042129 Gasterosteus aculeatus 81.40 0.00e+00 880.00
IUUC-Gma-044273 Glycine max 43.73 2.00e-117 415.00
IUUC-Ggo-045262 Gorilla gorilla 95.44 0.00e+00 1001.00
IUUC-Hsa-046036 Homo sapiens 95.44 0.00e+00 1001.00
IUUC-Hvu-047442 Hordeum vulgare 39.77 2.00e-64 238.00
IUUC-Itr-048169 Ictidomys tridecemlineatus 94.87 0.00e+00 958.00
IUUC-Lch-050105 Latimeria chalumnae 86.31 0.00e+00 927.00
IUUC-Lpe-050976 Leersia perrieri 42.62 4.00e-116 411.00
IUUC-Loc-052042 Lepisosteus oculatus 71.28 0.00e+00 656.00
IUUC-Lma-053143 Leptosphaeria maculans 32.87 2.00e-60 227.00
IUUC-Laf-053451 Loxodonta africana 96.01 0.00e+00 1002.00
IUUC-Mcc-055786 Macaca mulatta 95.44 0.00e+00 1001.00
IUUC-Meu-056161 Macropus eugenii 99.17 5.00e-141 494.00
IUUC-Mor-057215 Magnaporthe oryzae 32.08 3.00e-53 202.00
IUUC-Mpo-057419 Magnaporthe poae 30.02 3.00e-47 182.00
IUUC-Mtr-057756 Medicago truncatula 42.09 3.00e-112 398.00
IUUC-Mla-059085 Melampsora laricipopulina 36.46 4.00e-82 298.00
IUUC-Mga-060158 Meleagris gallopavo 87.98 0.00e+00 882.00
IUUC-Mvi-060441 Microbotryum violaceum 36.28 5.00e-75 275.00
IUUC-Mmr-061085 Microcebus murinus 95.44 0.00e+00 1001.00
IUUC-Mdo-061804 Monodelphis domestica 95.44 0.00e+00 1000.00
IUUC-Mmu-063608 Mus musculus 96.20 0.00e+00 1009.00
IUUC-Mac-064972 Musa acuminata 42.44 3.00e-113 401.00
IUUC-Mpu-065700 Mustela putorius furo 94.87 0.00e+00 996.00
IUUC-Mlu-068223 Myotis lucifugus 94.15 0.00e+00 997.00
IUUC-Nfi-068504 Neosartorya fischeri 35.66 6.00e-75 274.00
IUUC-Ncr-068729 Neurospora crassa 35.07 2.00e-59 223.00
IUUC-Nle-069754 Nomascus leucogenys 95.44 0.00e+00 1001.00
IUUC-Opr-070621 Ochotona princeps 91.33 0.00e+00 936.00
IUUC-Ont-071377 Oreochromis niloticus 81.40 0.00e+00 859.00
IUUC-Oan-073498 Ornithorhynchus anatinus 94.02 4.00e-97 347.00
IUUC-Ocu-074182 Oryctolagus cuniculus 96.21 0.00e+00 1012.00
IUUC-Oba-075509 Oryza barthii 41.80 1.00e-117 416.00
IUUC-Obr-076480 Oryza brachyantha 42.73 7.00e-119 420.00
IUUC-Ogl-077052 Oryza glaberrima 41.80 9.00e-118 417.00
IUUC-Ogu-078919 Oryza glumaepatula 41.80 1.00e-117 416.00
IUUC-Oin-079357 Oryza indica 41.11 7.00e-111 394.00
IUUC-Olo-080376 Oryza longistaminata 41.45 8.00e-106 377.00
IUUC-Ome-081973 Oryza meridionalis 40.98 1.00e-105 376.00
IUUC-Oni-082849 Oryza nivara 41.99 2.00e-118 419.00
IUUC-Opu-083243 Oryza punctata 41.62 5.00e-117 414.00
IUUC-Oru-084613 Oryza rufipogon 42.07 1.00e-117 416.00
IUUC-Osa-085407 Oryza sativa 41.77 3.00e-117 415.00
IUUC-Ola-086566 Oryzias latipes 80.64 0.00e+00 850.00
IUUC-Olu-087757 Ostreococcus lucimarinus 37.67 7.00e-91 327.00
IUUC-Oga-089010 Otolemur garnettii 90.93 0.00e+00 947.00
IUUC-Oar-089638 Ovis aries 95.25 0.00e+00 999.00
IUUC-Ptr-091141 Pan troglodytes 95.44 0.00e+00 1001.00
IUUC-Pan-092662 Papio anubis 95.44 0.00e+00 1001.00
IUUC-Psi-093777 Pelodiscus sinensis 97.37 0.00e+00 822.00
IUUC-Pno-095115 Phaeosphaeria nodorum 33.33 5.00e-61 228.00
IUUC-Ppa-095841 Physcomitrella patens 42.96 6.00e-117 414.00
IUUC-Pfo-096390 Poecilia formosa 80.65 0.00e+00 859.00
IUUC-Pab-098250 Pongo abelii 93.69 0.00e+00 934.00
IUUC-Pop-099854 Populus trichocarpa 43.25 2.00e-116 412.00
IUUC-Pca-100553 Procavia capensis 94.87 0.00e+00 992.00
IUUC-Ppe-101383 Prunus persica 42.41 2.00e-110 392.00
IUUC-Pva-102189 Pteropus vampyrus 95.06 0.00e+00 999.00
IUUC-Pgr-103304 Puccinia graminis 35.34 5.00e-80 291.00
IUUC-Ptt-103984 Puccinia triticina 36.00 2.00e-85 309.00
IUUC-Pte-104385 Pyrenophora teres 31.45 8.00e-65 241.00
IUUC-Pyt-104697 Pyrenophora triticirepentis 31.85 4.00e-66 244.00
IUUC-Rno-105581 Rattus norvegicus 94.87 0.00e+00 997.00
IUUC-Sja-107697 Schizosaccharomyces japonicus 29.67 1.00e-31 130.00
IUUC-Spo-108315 Schizosaccharomyces pombe 31.49 8.00e-42 164.00
IUUC-Ssl-108628 Sclerotinia sclerotiorum 33.33 3.00e-60 225.00
IUUC-Smo-109648 Selaginella moellendorffii 43.12 4.00e-118 417.00
IUUC-Sit-109873 Setaria italica 41.80 6.00e-116 411.00
IUUC-Sly-111673 Solanum lycopersicum 43.49 3.00e-109 388.00
IUUC-Stu-112125 Solanum tuberosum 43.31 2.00e-108 385.00
IUUC-Sbi-114696 Sorghum bicolor 40.68 2.00e-104 372.00
IUUC-Sre-115134 Sporisorium reilianum 30.28 7.00e-68 251.00
IUUC-Ssc-116260 Sus scrofa 95.06 0.00e+00 998.00
IUUC-Tgu-116533 Taeniopygia guttata 93.54 0.00e+00 988.00
IUUC-Tru-117800 Takifugu rubripes 80.83 0.00e+00 882.00
IUUC-Tsy-118980 Tarsius syrichta 89.65 0.00e+00 907.00
IUUC-Tni-120334 Tetraodon nigroviridis 65.28 0.00e+00 691.00
IUUC-Tca-121807 Theobroma cacao 42.33 5.00e-117 414.00
IUUC-Tre-121920 Trichoderma reesei 31.52 1.00e-58 220.00
IUUC-Tvi-122294 Trichoderma virens 31.39 3.00e-51 196.00
IUUC-Tae-125713 Triticum aestivum 42.17 1.00e-120 426.00
IUUC-Tur-126664 Triticum urartu 38.07 2.00e-110 392.00
IUUC-Tme-127026 Tuber melanosporum 32.82 1.00e-64 240.00
IUUC-Tbe-127582 Tupaia belangeri 99.39 0.00e+00 678.00
IUUC-Ttr-128313 Tursiops truncatus 94.87 0.00e+00 989.00
IUUC-Uma-129626 Ustilago maydis 32.02 1.00e-70 260.00
IUUC-Vda-129699 Verticillium dahliae 33.80 9.00e-64 237.00
IUUC-Vpa-130593 Vicugna pacos 94.12 0.00e+00 886.00
IUUC-Vvi-131668 Vitis vinifera 42.41 3.00e-116 411.00
IUUC-Xtr-132186 Xenopus tropicalis 81.34 0.00e+00 756.00
IUUC-Xma-133212 Xiphophorus maculatus 80.46 0.00e+00 854.00
IUUC-Yli-134607 Yarrowia lipolytica 49.35 1.00e-37 148.00
IUUC-Zma-135662 Zea mays 42.99 6.00e-118 417.00
Created Date 25-Jun-2017

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