iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037524

Ensembl Protein ID

ENSFALP00000000012.1

UniProt Accession

U3JB58; U3JB58_FICAL

Genbank Protein ID

ENSFALP00000000012

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021655

Gene Name

PPARG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000000011.1	ENSFALT00000000012.1	ENSFALP00000000012.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.21	0.00e+00	883.00	IUUC-Hsa-046916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MVDTEMPFWP LNFGISPVDL SAMDDHTHSF DIKPFTTVDF SSISSPHYED LPLARAEQSG 60
LDYKYDIKLQ DCQSAIKMEP PSPPYFSEKV QLYSKPQEEA SSSLMAIECR VCGDKASGFH 120

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Nucleotide Sequence
(Fasta)

GGATTACAAT GGTTGACACA GAAATGCCGT TTTGGCCCCT GAATTTTGGA ATCAGCCCTG 60
TGGACCTGTC AGCCATGGAT GATCACACAC ATTCCTTTGA CATCAAGCCC TTCACCACCG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003077--1Cnucl_rcpt_G
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR022590--PPARgamma_N
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF12577--PPARgamma_N
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01291--PROXISOMPAGR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0090575--C:RNA polymerase II transcription factor complex
GO:0008144--F:drug binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048469--P:cell maturation
GO:0032869--P:cellular response to insulin stimulus
GO:0042593--P:glucose homeostasis
GO:0042953--P:lipoprotein transport
GO:0045713--P:low-density lipoprotein particle receptor biosynthetic process
GO:0010742--P:macrophage derived foam cell differentiation
GO:0030224--P:monocyte differentiation
GO:0010887--P:negative regulation of cholesterol storage
GO:0060336--P:negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035357--P:peroxisome proliferator activated receptor signaling pathway
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008217--P:regulation of blood pressure
GO:0055098--P:response to low-density lipoprotein particle
GO:0032526--P:response to retinoic acid
GO:0006351--P:transcription, DNA-templated

KEGG

fab:101815733

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001214	Ailuropoda melanoleuca	92.84	0.00e+00	885.00
IUUC-Aca-005129	Anolis carolinensis	93.47	0.00e+00	905.00
IUUC-Ame-010818	Astyanax mexicanus	65.38	0.00e+00	639.00
IUUC-Bta-013226	Bos taurus	92.63	0.00e+00	883.00
IUUC-Cja-019236	Callithrix jacchus	92.84	0.00e+00	889.00
IUUC-Cfa-020281	Canis familiaris	92.63	0.00e+00	889.00
IUUC-Cpo-021587	Cavia porcellus	90.32	0.00e+00	865.00
IUUC-Csa-023400	Chlorocebus sabaeus	92.21	0.00e+00	883.00
IUUC-Cho-024593	Choloepus hoffmanni	81.05	0.00e+00	757.00
IUUC-Dre-028176	Danio rerio	62.10	2.00e-156	545.00
IUUC-Dno-029063	Dasypus novemcinctus	92.00	0.00e+00	880.00
IUUC-Ete-032520	Echinops telfairi	90.74	0.00e+00	859.00
IUUC-Fca-035935	Felis catus	93.26	0.00e+00	891.00
IUUC-Gga-041223	Gallus gallus	96.00	0.00e+00	923.00
IUUC-Gac-042156	Gasterosteus aculeatus	62.52	0.00e+00	643.00
IUUC-Ggo-045265	Gorilla gorilla	92.21	0.00e+00	884.00
IUUC-Hsa-046916	Homo sapiens	92.21	0.00e+00	883.00
IUUC-Lch-049759	Latimeria chalumnae	79.24	0.00e+00	669.00
IUUC-Loc-051870	Lepisosteus oculatus	75.00	0.00e+00	758.00
IUUC-Laf-054483	Loxodonta africana	91.58	0.00e+00	877.00
IUUC-Meu-056587	Macropus eugenii	92.21	0.00e+00	857.00
IUUC-Mga-059530	Meleagris gallopavo	96.00	0.00e+00	923.00
IUUC-Mmr-060576	Microcebus murinus	92.21	0.00e+00	877.00
IUUC-Mdo-061854	Monodelphis domestica	92.63	0.00e+00	888.00
IUUC-Mmu-063724	Mus musculus	91.37	0.00e+00	878.00
IUUC-Mpu-066888	Mustela putorius furo	92.42	0.00e+00	916.00
IUUC-Mlu-067978	Myotis lucifugus	92.42	0.00e+00	918.00
IUUC-Nle-070069	Nomascus leucogenys	92.42	0.00e+00	884.00
IUUC-Opr-070630	Ochotona princeps	90.08	0.00e+00	711.00
IUUC-Ont-071399	Oreochromis niloticus	60.97	0.00e+00	629.00
IUUC-Ocu-074862	Oryctolagus cuniculus	92.42	0.00e+00	882.00
IUUC-Ola-087266	Oryzias latipes	56.42	3.00e-159	554.00
IUUC-Oga-089143	Otolemur garnettii	92.63	0.00e+00	885.00
IUUC-Oar-089725	Ovis aries	92.63	0.00e+00	883.00
IUUC-Ptr-091580	Pan troglodytes	92.21	0.00e+00	883.00
IUUC-Psi-093041	Pelodiscus sinensis	92.84	0.00e+00	885.00
IUUC-Ppa-095660	Physcomitrella patens	27.85	1.90e-01	32.00
IUUC-Pfo-097438	Poecilia formosa	59.96	0.00e+00	627.00
IUUC-Pab-098333	Pongo abelii	91.58	0.00e+00	870.00
IUUC-Pca-100861	Procavia capensis	91.58	0.00e+00	875.00
IUUC-Pva-102186	Pteropus vampyrus	81.47	0.00e+00	761.00
IUUC-Rno-105583	Rattus norvegicus	91.58	0.00e+00	879.00
IUUC-Sha-107484	Sarcophilus harrisii	92.63	0.00e+00	888.00
IUUC-Sar-112996	Sorex araneus	81.80	2.00e-178	618.00
IUUC-Ssc-115945	Sus scrofa	92.63	0.00e+00	885.00
IUUC-Tsy-119098	Tarsius syrichta	82.32	0.00e+00	760.00
IUUC-Tni-120902	Tetraodon nigroviridis	60.88	1.00e-174	605.00
IUUC-Tbe-127225	Tupaia belangeri	69.89	5.00e-178	617.00
IUUC-Ttr-129292	Tursiops truncatus	92.84	0.00e+00	884.00
IUUC-Vpa-130378	Vicugna pacos	86.40	0.00e+00	697.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence