iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089289

Ensembl Protein ID

ENSOARP00000002172.1

UniProt Accession

W5NVH6; W5NVH6_SHEEP

Genbank Protein ID

ENSOARP00000002172

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01068105

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000002069.1	ENSOART00000002223.1	ENSOARP00000002172.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	2.50e-08	34.2	285	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvCqkm...vdqtdfeeHlDeCl 24
           ++C++Cqk    +++t++++H+++Cl
   Q: 285  FFCQICQKNlsaMNVTRRQQHVNRCL 310
           89***********************8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

EASSVNEAWR GSHSGSLSHL CTGPHIDPHF SEDQPENLQT RQMMDESDDD FQELCASFFQ 60
RVKKNGPKEV SKEKKTQKAS NSTQIRSKPK RTKPTASKSK TPQGPTERKT CPGSQVPRTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGCTTCCA GTGTGAATGA GGCCTGGCGA GGCTCACACT CGGGTTCACT TTCTCACCTG 60
TGCACAGGCC CGCACATCGA CCCTCACTTC TCCGAAGACC AGCCTGAAAA CCTTCAAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	63.94	0.00e+00	1046.00
IUUC-Apl-003261	Anas platyrhynchos	37.74	3.00e-142	499.00
IUUC-Aca-004455	Anolis carolinensis	68.42	4.00e-19	85.50
IUUC-Ame-010993	Astyanax mexicanus	38.18	3.00e-11	61.60
IUUC-Bta-013472	Bos taurus	89.48	0.00e+00	1872.00
IUUC-Cel-018663	Caenorhabditis elegans	38.64	6.00e-03	36.20
IUUC-Cja-019406	Callithrix jacchus	58.02	0.00e+00	1422.00
IUUC-Cfa-020129	Canis familiaris	61.44	0.00e+00	1075.00
IUUC-Cpo-021944	Cavia porcellus	51.60	0.00e+00	1110.00
IUUC-Csa-023941	Chlorocebus sabaeus	64.91	2.00e-132	466.00
IUUC-Cho-024847	Choloepus hoffmanni	62.34	1.00e-149	524.00
IUUC-Cin-025405	Ciona intestinalis	44.23	2.00e-08	53.10
IUUC-Csv-025916	Ciona savignyi	37.93	2.00e-08	52.80
IUUC-Dre-027764	Danio rerio	31.57	5.00e-78	286.00
IUUC-Dno-030083	Dasypus novemcinctus	55.55	0.00e+00	834.00
IUUC-Dor-031129	Dipodomys ordii	48.30	2.00e-170	593.00
IUUC-Dse-031510	Dothistroma septosporum	36.11	6.70e-02	33.50
IUUC-Ete-032536	Echinops telfairi	41.29	4.00e-77	283.00
IUUC-Eca-033407	Equus caballus	65.17	0.00e+00	829.00
IUUC-Eeu-034473	Erinaceus europaeus	56.15	5.00e-22	100.00
IUUC-Fca-035730	Felis catus	62.80	0.00e+00	1028.00
IUUC-Fal-036850	Ficedula albicollis	42.82	4.00e-132	466.00
IUUC-Gmo-038677	Gadus morhua	40.34	3.00e-25	110.00
IUUC-Gga-041088	Gallus gallus	40.62	3.00e-130	460.00
IUUC-Gac-041824	Gasterosteus aculeatus	76.32	1.00e-12	66.60
IUUC-Ggo-045642	Gorilla gorilla	58.12	0.00e+00	779.00
IUUC-Hsa-047035	Homo sapiens	59.45	0.00e+00	1045.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	58.00	0.00e+00	979.00
IUUC-Kpa-049328	Komagataella pastoris	28.38	2.00e-03	37.40
IUUC-Lch-050364	Latimeria chalumnae	40.56	8.00e-68	252.00
IUUC-Loc-052423	Lepisosteus oculatus	39.88	5.00e-41	164.00
IUUC-Laf-053910	Loxodonta africana	56.35	0.00e+00	842.00
IUUC-Mcc-055883	Macaca mulatta	59.54	0.00e+00	1001.00
IUUC-Meu-056224	Macropus eugenii	47.45	2.00e-79	291.00
IUUC-Mga-059880	Meleagris gallopavo	43.68	7.00e-129	455.00
IUUC-Mvi-060510	Microbotryum violaceum	38.18	1.00e-05	45.40
IUUC-Mmr-061715	Microcebus murinus	58.62	0.00e+00	1021.00
IUUC-Mdo-062426	Monodelphis domestica	40.68	0.00e+00	662.00
IUUC-Mmu-063947	Mus musculus	58.75	0.00e+00	798.00
IUUC-Mpu-066184	Mustela putorius furo	61.12	0.00e+00	1047.00
IUUC-Mlu-067533	Myotis lucifugus	65.10	0.00e+00	1045.00
IUUC-Nle-069204	Nomascus leucogenys	57.94	0.00e+00	998.00
IUUC-Opr-070377	Ochotona princeps	59.03	0.00e+00	818.00
IUUC-Ont-072551	Oreochromis niloticus	33.33	2.00e-62	234.00
IUUC-Oan-073350	Ornithorhynchus anatinus	46.48	3.00e-102	365.00
IUUC-Ocu-074915	Oryctolagus cuniculus	57.39	0.00e+00	826.00
IUUC-Ola-087360	Oryzias latipes	40.39	3.00e-33	135.00
IUUC-Oga-089106	Otolemur garnettii	54.53	0.00e+00	641.00
IUUC-Ptr-091469	Pan troglodytes	59.12	0.00e+00	1028.00
IUUC-Pan-091841	Papio anubis	56.44	6.00e-170	592.00
IUUC-Psi-093842	Pelodiscus sinensis	46.35	6.00e-127	449.00
IUUC-Pma-094732	Petromyzon marinus	51.92	3.00e-08	51.60
IUUC-Pfo-097299	Poecilia formosa	39.07	2.00e-32	135.00
IUUC-Pab-098271	Pongo abelii	58.25	0.00e+00	999.00
IUUC-Pca-100721	Procavia capensis	53.67	0.00e+00	847.00
IUUC-Pva-102276	Pteropus vampyrus	67.41	0.00e+00	1105.00
IUUC-Rno-105619	Rattus norvegicus	53.82	0.00e+00	926.00
IUUC-Sha-106722	Sarcophilus harrisii	44.05	0.00e+00	667.00
IUUC-Sar-113673	Sorex araneus	58.33	3.00e-82	300.00
IUUC-Sre-115039	Sporisorium reilianum	33.87	2.00e-05	43.10
IUUC-Ssc-115383	Sus scrofa	64.61	0.00e+00	962.00
IUUC-Tgu-117243	Taeniopygia guttata	47.76	2.00e-81	295.00
IUUC-Tru-118092	Takifugu rubripes	35.96	6.00e-32	130.00
IUUC-Tsy-119362	Tarsius syrichta	63.86	2.00e-160	560.00
IUUC-Tni-120380	Tetraodon nigroviridis	67.14	6.00e-21	94.40
IUUC-Tbe-127404	Tupaia belangeri	50.67	6.00e-79	290.00
IUUC-Ttr-128317	Tursiops truncatus	74.12	0.00e+00	1465.00
IUUC-Uma-129640	Ustilago maydis	35.48	9.00e-06	44.30
IUUC-Xtr-132533	Xenopus tropicalis	40.61	2.00e-88	321.00
IUUC-Xma-134059	Xiphophorus maculatus	40.00	2.00e-34	141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence