iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062707

UUCD1 version

UUC-MoD-00814

Ensembl Protein ID

ENSMODP00000020454.4

UniProt Accession

F7ERS5; F7ERS5_MONDO

Protein Name

Coronin

Gene Name

LOC100015171

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000016364.4	ENSMODT00000020814.4	ENSMODP00000020454.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-36	121.8	593	628
UBD/Beta-Prp	2.40e-45	155.1	68	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtg 33
           gHt+++++l+f    s + l+s+s+D t+++WDl +g
   Q: 593  GHTEKIYSLRFhplaS-DVLASSSYDLTVRIWDLQEG 628
           8**********99865.889*************9876 PP

UBD/Beta-Prp

   S: 85   kcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
           k v  l  h+d v++ +fsp +++ lv+Gs+dr++++w l+     ++       +l ++d  v  +++hp+++ +  ++ D++v++Wd
   Q: 68   KNVAYLGCHSDLVTDFDFSPfDDHLLVTGSADRMVKLWRLPATATDQDlpsapgvVLGPEDCQVELLKFHPTSDTVLVSTSDKVVKVWD 156
           555566679***********888****************998888888888**********************99999*********** PP
   S: 166  lktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfs.pnderlvsgs....sDgsiri 248
           l+ +  l++l + h d+v+s++++sng  l +  +d+ ++++d + + +  ++ +gh++   s  ++ + +e+l+s++     +  +++
   Q: 157  LALKHTLTELGS-HSDQVQSVAWSSNGVLLGTSCKDKHLRVFDPRtKPTASQSTQGHENHKDSQLVWtNSQEHLLSTGlnqmREHEVKL 244
           **********88.********************************5556689999******9999996778999999999999****** PP
   S: 249  Wdlrs.gdllktlqlhnssvisvavlsfgdnvlvlgse.d 286
           Wd+r     l++++lh s  + + +l+ +   l+lg++ +
   Q: 245  WDTRCfASALTSFTLHTSPGSLIPLLDADSGLLILGGKgE 284
           **98635667788888888888888887777777777744 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MNRFKVSKFR HTEARPPRKE AWINDIRAGA ASSYGNHIKS SCSLIVFNTD QPGTLGIVPL 60
ESQDRNKKNV AYLGCHSDLV TDFDFSPFDD HLLVTGSADR MVKLWRLPAT ATDQDLPSAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGGGAGA CGGGGATTGG CCGAGAGGAG GGAGGAGGCG TGGCCTCGGG CGGCGTGCGG 60
CGGGGTCTGA GTGGGGGTGG AGGTTGGTTT CTCTGACACC GAGTACTGCT GCTGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR027331--CORO7
IPR015505--Coronin
IPR015048--DUF1899
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF08953--DUF1899
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0007015--P:actin filament organization
GO:0016477--P:cell migration
GO:0030010--P:establishment of cell polarity
GO:0007030--P:Golgi organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002235	Ailuropoda melanoleuca	73.76	0.00e+00	1202.00
IUUC-Apl-004126	Anas platyrhynchos	55.11	2.00e-109	389.00
IUUC-Aca-005201	Anolis carolinensis	67.86	0.00e+00	816.00
IUUC-Ame-011310	Astyanax mexicanus	54.38	2.00e-74	271.00
IUUC-Bta-012843	Bos taurus	76.32	0.00e+00	1273.00
IUUC-Cel-018204	Caenorhabditis elegans	35.48	4.00e-66	246.00
IUUC-Cja-019024	Callithrix jacchus	72.06	0.00e+00	1166.00
IUUC-Cfa-020626	Canis familiaris	75.78	0.00e+00	1241.00
IUUC-Cpo-022429	Cavia porcellus	74.05	0.00e+00	1309.00
IUUC-Csa-023919	Chlorocebus sabaeus	75.54	0.00e+00	1241.00
IUUC-Cin-025202	Ciona intestinalis	46.37	3.00e-121	429.00
IUUC-Csv-026236	Ciona savignyi	41.85	7.00e-139	487.00
IUUC-Dre-028759	Danio rerio	61.83	0.00e+00	766.00
IUUC-Dno-029234	Dasypus novemcinctus	63.25	0.00e+00	912.00
IUUC-Dor-030242	Dipodomys ordii	77.41	0.00e+00	1257.00
IUUC-Dme-032156	Drosophila melanogaster	42.76	1.00e-113	405.00
IUUC-Ete-032862	Echinops telfairi	72.15	0.00e+00	1116.00
IUUC-Eca-033902	Equus caballus	72.07	0.00e+00	1181.00
IUUC-Eeu-034540	Erinaceus europaeus	58.39	5.00e-155	541.00
IUUC-Fca-036335	Felis catus	74.39	0.00e+00	1263.00
IUUC-Fal-037278	Ficedula albicollis	74.73	0.00e+00	704.00
IUUC-Gmo-038846	Gadus morhua	48.44	0.00e+00	764.00
IUUC-Gga-041144	Gallus gallus	59.64	0.00e+00	1024.00
IUUC-Gac-041680	Gasterosteus aculeatus	54.88	0.00e+00	944.00
IUUC-Ggo-045469	Gorilla gorilla	77.80	1.00e-171	597.00
IUUC-Hsa-046873	Homo sapiens	74.89	0.00e+00	1222.00
IUUC-Itr-048351	Ictidomys tridecemlineatus	74.49	0.00e+00	1278.00
IUUC-Loc-052682	Lepisosteus oculatus	63.19	0.00e+00	864.00
IUUC-Laf-053869	Loxodonta africana	63.12	0.00e+00	863.00
IUUC-Mcc-054896	Macaca mulatta	75.75	0.00e+00	1262.00
IUUC-Meu-056428	Macropus eugenii	88.86	0.00e+00	1509.00
IUUC-Mga-059389	Meleagris gallopavo	63.85	0.00e+00	1101.00
IUUC-Mvi-060231	Microbotryum violaceum	34.00	2.00e-59	224.00
IUUC-Mmr-060935	Microcebus murinus	76.94	0.00e+00	1286.00
IUUC-Mmu-063976	Mus musculus	74.81	0.00e+00	1293.00
IUUC-Mpu-066441	Mustela putorius furo	74.41	0.00e+00	1191.00
IUUC-Mlu-067524	Myotis lucifugus	75.24	0.00e+00	1283.00
IUUC-Opr-071099	Ochotona princeps	72.65	0.00e+00	1146.00
IUUC-Ont-071673	Oreochromis niloticus	68.72	0.00e+00	653.00
IUUC-Oan-072860	Ornithorhynchus anatinus	76.23	0.00e+00	848.00
IUUC-Ocu-074794	Oryctolagus cuniculus	73.42	0.00e+00	1204.00
IUUC-Ola-086479	Oryzias latipes	55.21	0.00e+00	977.00
IUUC-Oga-088030	Otolemur garnettii	71.03	0.00e+00	1154.00
IUUC-Oar-090379	Ovis aries	66.81	0.00e+00	1053.00
IUUC-Ptr-091006	Pan troglodytes	70.77	0.00e+00	1123.00
IUUC-Pan-092428	Papio anubis	75.84	0.00e+00	1258.00
IUUC-Psi-093624	Pelodiscus sinensis	55.32	7.00e-116	410.00
IUUC-Pfo-096558	Poecilia formosa	57.31	0.00e+00	1011.00
IUUC-Pab-098298	Pongo abelii	65.06	0.00e+00	996.00
IUUC-Pca-100305	Procavia capensis	67.71	0.00e+00	826.00
IUUC-Pva-102702	Pteropus vampyrus	74.08	0.00e+00	1032.00
IUUC-Pgr-103449	Puccinia graminis	31.19	9.00e-42	165.00
IUUC-Rno-105934	Rattus norvegicus	71.17	0.00e+00	1254.00
IUUC-Sha-106795	Sarcophilus harrisii	85.26	0.00e+00	1449.00
IUUC-Sar-112987	Sorex araneus	78.87	2.00e-104	373.00
IUUC-Ssc-116071	Sus scrofa	75.68	0.00e+00	1290.00
IUUC-Tgu-116813	Taeniopygia guttata	66.48	1.00e-176	612.00
IUUC-Tru-118359	Takifugu rubripes	57.20	0.00e+00	1020.00
IUUC-Tni-119997	Tetraodon nigroviridis	68.32	0.00e+00	665.00
IUUC-Ttr-129020	Tursiops truncatus	72.76	0.00e+00	1261.00
IUUC-Xtr-132552	Xenopus tropicalis	62.57	1.00e-118	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence