iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069043

Ensembl Protein ID

ENSNLEP00000011887.2

UniProt Accession

G1RF87; G1RF87_NOMLE

Genbank Protein ID

ENSNLEP00000011887

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01033436

Gene Name

ARHGAP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000009755.2	ENSNLET00000012469.2	ENSNLEP00000011887.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-12	47.7	622	674

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++++G v + + + +q+ gWl+g  +l+gk Gl+Pen+ve
   Q: 622  KAKALYACKAEHDSELSFTAGTVFDNV-HPSQEPGWLEG--TLNGKTGLIPENYVE 674
           679************************.***********..8*************8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPAXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXIGA AKEAKKKYDK ETEKYCGILE 60
KHLNLSSKKK ESQLQEADSQ VDLVRQHFYE VSLEYVFKVQ EVQERKMFEF VEPLLAFLQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAGCGA GNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NATCGGGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0005543--F:phospholipid binding
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	93.25	0.00e+00	893.00
IUUC-Apl-003321	Anas platyrhynchos	87.94	0.00e+00	844.00
IUUC-Aca-004570	Anolis carolinensis	85.76	0.00e+00	976.00
IUUC-Ame-011422	Astyanax mexicanus	73.11	0.00e+00	723.00
IUUC-Bta-013262	Bos taurus	93.46	0.00e+00	895.00
IUUC-Cel-018542	Caenorhabditis elegans	40.00	1.00e-90	327.00
IUUC-Cja-019208	Callithrix jacchus	95.51	0.00e+00	999.00
IUUC-Cfa-020928	Canis familiaris	93.43	0.00e+00	1002.00
IUUC-Cpo-021338	Cavia porcellus	92.88	0.00e+00	901.00
IUUC-Csa-023570	Chlorocebus sabaeus	95.35	0.00e+00	997.00
IUUC-Cin-025725	Ciona intestinalis	40.18	2.00e-90	327.00
IUUC-Dre-027525	Danio rerio	60.00	5.00e-141	494.00
IUUC-Dno-029143	Dasypus novemcinctus	92.71	0.00e+00	890.00
IUUC-Dor-030697	Dipodomys ordii	93.27	0.00e+00	881.00
IUUC-Dme-032147	Drosophila melanogaster	41.30	2.00e-94	340.00
IUUC-Ete-032645	Echinops telfairi	80.41	0.00e+00	747.00
IUUC-Eca-033791	Equus caballus	93.87	0.00e+00	897.00
IUUC-Eeu-035202	Erinaceus europaeus	77.66	1.00e-111	397.00
IUUC-Fca-036131	Felis catus	93.66	0.00e+00	901.00
IUUC-Fal-037129	Ficedula albicollis	87.34	0.00e+00	930.00
IUUC-Gga-041023	Gallus gallus	87.68	0.00e+00	976.00
IUUC-Gac-041728	Gasterosteus aculeatus	52.88	2.00e-129	456.00
IUUC-Ggo-044863	Gorilla gorilla	94.44	0.00e+00	887.00
IUUC-Hsa-046471	Homo sapiens	94.81	0.00e+00	894.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	92.69	0.00e+00	914.00
IUUC-Lch-050300	Latimeria chalumnae	75.15	0.00e+00	759.00
IUUC-Loc-052782	Lepisosteus oculatus	74.10	0.00e+00	767.00
IUUC-Laf-053585	Loxodonta africana	92.84	0.00e+00	889.00
IUUC-Mcc-055458	Macaca mulatta	95.51	0.00e+00	1004.00
IUUC-Meu-056107	Macropus eugenii	72.25	0.00e+00	686.00
IUUC-Mga-059914	Meleagris gallopavo	87.34	0.00e+00	966.00
IUUC-Mmr-060728	Microcebus murinus	93.65	0.00e+00	884.00
IUUC-Mdo-062387	Monodelphis domestica	87.17	0.00e+00	903.00
IUUC-Mmu-063756	Mus musculus	92.56	0.00e+00	900.00
IUUC-Opr-071168	Ochotona princeps	81.91	0.00e+00	770.00
IUUC-Ont-072338	Oreochromis niloticus	72.29	0.00e+00	710.00
IUUC-Oan-073441	Ornithorhynchus anatinus	88.77	0.00e+00	970.00
IUUC-Ocu-073915	Oryctolagus cuniculus	90.82	0.00e+00	905.00
IUUC-Ola-086319	Oryzias latipes	69.18	0.00e+00	658.00
IUUC-Oar-089349	Ovis aries	92.86	0.00e+00	889.00
IUUC-Ptr-091027	Pan troglodytes	94.62	0.00e+00	892.00
IUUC-Pan-092791	Papio anubis	95.67	0.00e+00	1001.00
IUUC-Psi-093144	Pelodiscus sinensis	87.36	0.00e+00	1015.00
IUUC-Pfo-097265	Poecilia formosa	58.47	4.00e-147	514.00
IUUC-Pab-097783	Pongo abelii	94.42	0.00e+00	892.00
IUUC-Pva-102980	Pteropus vampyrus	93.05	0.00e+00	931.00
IUUC-Rno-105142	Rattus norvegicus	93.59	0.00e+00	1031.00
IUUC-Sha-107213	Sarcophilus harrisii	88.92	0.00e+00	1008.00
IUUC-Tgu-117313	Taeniopygia guttata	80.20	3.00e-175	607.00
IUUC-Tru-117767	Takifugu rubripes	67.57	0.00e+00	701.00
IUUC-Tsy-119150	Tarsius syrichta	93.88	0.00e+00	904.00
IUUC-Tni-119893	Tetraodon nigroviridis	69.57	0.00e+00	711.00
IUUC-Ttr-129028	Tursiops truncatus	76.84	0.00e+00	696.00
IUUC-Xtr-131767	Xenopus tropicalis	78.27	0.00e+00	785.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence