iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053524

UUCD1 version

UUC-LoA-01000

Ensembl Protein ID

ENSLAFP00000010129.1

UniProt Accession

G3T8U0; G3T8U0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE2L6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000012121.1	ENSLAFT00000012119.1	ENSLAFP00000010129.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-38	131.9	6	142

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l+++ p +++  +++++++  w++l+l p++ pY+ ++F+l+i+f+e+YPfkPP+vkf+tki+hPnv+enG+vCl i+ ++
   Q: 6    RVAKELEDLQSQLPRYLQNLVSEDANVLVWHALLL-PDQPPYNLRAFNLRIDFSEEYPFKPPTVKFTTKIYHPNVDENGQVCLPII-SN 92
           899********************************.**************************************************.59 PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           + W+p+++  +vl +++ ++++ + ++pl+++ a+ll +++e++kk++re
   Q: 93   KYWKPCTKTCQVLEALNVMVNKLELDQPLRVDLADLLVRDPEQFKKNARE 142
           ***********************************************985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSARKRVAKE LEDLQSQLPR YLQNLVSEDA NVLVWHALLL PDQPPYNLRA FNLRIDFSEE 60
YPFKPPTVKF TTKIYHPNVD ENGQVCLPII SNKYWKPCTK TCQVLEALNV MVNKLELDQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGCGA GGAAGCGGGT GGCGAAGGTA ACCGCGTTTG GGACACTCCT TCTCCCCCGC 60
TCCTCCTCCC TCCGTCTCTT TCCCGATTCC CTCCCCCCTC CACCCCTTCC TCGGCTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process

KEGG

lav:100656917

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001818	Ailuropoda melanoleuca	68.63	1.00e-61	228.00
IUUC-Bta-012539	Bos taurus	67.97	2.00e-59	220.00
IUUC-Cja-019456	Callithrix jacchus	77.12	3.00e-68	250.00
IUUC-Cfa-021275	Canis familiaris	67.32	5.00e-60	223.00
IUUC-Cpo-022261	Cavia porcellus	62.09	2.00e-53	201.00
IUUC-Csa-023794	Chlorocebus sabaeus	73.51	2.00e-63	233.00
IUUC-Cho-024821	Choloepus hoffmanni	76.39	1.00e-61	228.00
IUUC-Dno-029632	Dasypus novemcinctus	76.47	1.00e-65	241.00
IUUC-Dor-030595	Dipodomys ordii	69.64	3.00e-44	170.00
IUUC-Eca-033746	Equus caballus	75.82	5.00e-67	246.00
IUUC-Fca-035417	Felis catus	71.24	9.00e-64	235.00
IUUC-Ggo-045537	Gorilla gorilla	73.86	3.00e-65	240.00
IUUC-Hsa-045943	Homo sapiens	74.51	5.00e-66	242.00
IUUC-Itr-048889	Ictidomys tridecemlineatus	67.97	5.00e-59	219.00
IUUC-Mcc-054818	Macaca mulatta	72.85	6.00e-63	232.00
IUUC-Mmr-060799	Microcebus murinus	78.29	2.00e-68	251.00
IUUC-Mmu-063359	Mus musculus	67.32	6.00e-58	216.00
IUUC-Mpu-066122	Mustela putorius furo	65.54	1.00e-56	211.00
IUUC-Mlu-067283	Myotis lucifugus	70.59	1.00e-59	221.00
IUUC-Nle-069829	Nomascus leucogenys	73.86	2.00e-65	241.00
IUUC-Opr-071062	Ochotona princeps	66.01	3.00e-57	213.00
IUUC-Oan-073297	Ornithorhynchus anatinus	73.20	3.00e-39	153.00
IUUC-Ocu-074709	Oryctolagus cuniculus	67.59	1.00e-54	205.00
IUUC-Oga-088256	Otolemur garnettii	76.97	1.00e-66	244.00
IUUC-Oar-089370	Ovis aries	66.21	7.00e-55	205.00
IUUC-Ptr-091324	Pan troglodytes	74.51	5.00e-66	242.00
IUUC-Pan-092601	Papio anubis	73.10	1.00e-60	225.00
IUUC-Pab-098184	Pongo abelii	75.82	8.00e-68	248.00
IUUC-Pca-101080	Procavia capensis	84.03	3.00e-69	253.00
IUUC-Rno-104863	Rattus norvegicus	64.71	1.00e-57	214.00
IUUC-Sha-107162	Sarcophilus harrisii	58.17	4.00e-47	179.00
IUUC-Ssc-115506	Sus scrofa	76.47	4.00e-67	246.00
IUUC-Tsy-118811	Tarsius syrichta	63.89	4.00e-50	189.00
IUUC-Ttr-129266	Tursiops truncatus	74.51	4.00e-66	243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence