iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033297

Ensembl Protein ID

ENSECAP00000012448.1

UniProt Accession

F7C5Q3; F7C5Q3_HORSE

Protein Name

Uncharacterized protein

Gene Name

BCAR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014666.1	ENSECAT00000015483.1	ENSECAP00000012448.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.70e-11	42.6	8	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeq.degWlkgvkelegkrGlfPen 57
            ++lyd  a++ deL+++kGd+++v+e ++q   gW+ +   l+g++G++P n
   Q: 8    AKALYDNVAESPDELSFRKGDIMTVLERDTQgLDGWWLC--SLHGRQGIVPGN 58
           689***********************55555168*****..9*********98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LSPQNVLAKA LYDNVAESPD ELSFRKGDIM TVLERDTQGL DGWWLCSLHG RQGIVPGNRL 60
KILVGMHDKK PAGPGPGPPA TSALPQPGLH TPATQYTPML PAAYQPQPDS VYLVPTPSKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCTCCCC AGAATGTGCT GGCCAAAGCC CTGTATGACA ACGTGGCCGA GTCCCCCGAT 60
GAGCTCTCCT TCCGCAAGGG CGACATCATG ACGGTGCTAG AGCGGGACAC TCAGGGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028848--BCAR1
IPR021901--CAS_DUF3513
IPR014928--Serine_rich
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
IPR015224--Talin_cent

PROSITE

PS50002--SH3

Pfam

PF12026--DUF3513
PF08824--Serine_rich
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004871--F:signal transducer activity
GO:0007015--P:actin filament organization
GO:0050853--P:B cell receptor signaling pathway
GO:0060326--P:cell chemotaxis
GO:0035729--P:cellular response to hepatocyte growth factor stimulus
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0048012--P:hepatocyte growth factor receptor signaling pathway
GO:0007229--P:integrin-mediated signaling pathway
GO:0048008--P:platelet-derived growth factor receptor signaling pathway
GO:0010595--P:positive regulation of endothelial cell migration
GO:0048010--P:vascular endothelial growth factor receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001208	Ailuropoda melanoleuca	92.70	0.00e+00	1241.00
IUUC-Apl-003391	Anas platyrhynchos	37.97	1.00e-139	490.00
IUUC-Aca-004548	Anolis carolinensis	39.00	4.00e-142	498.00
IUUC-Ame-010839	Astyanax mexicanus	27.19	5.00e-33	136.00
IUUC-Bta-013197	Bos taurus	85.79	0.00e+00	1204.00
IUUC-Cja-018921	Callithrix jacchus	91.72	0.00e+00	1350.00
IUUC-Cfa-020772	Canis familiaris	95.16	0.00e+00	1352.00
IUUC-Cpo-022455	Cavia porcellus	90.27	0.00e+00	1281.00
IUUC-Csa-023660	Chlorocebus sabaeus	91.92	0.00e+00	1349.00
IUUC-Cin-025595	Ciona intestinalis	27.78	3.00e-67	249.00
IUUC-Dre-028389	Danio rerio	53.43	0.00e+00	820.00
IUUC-Dno-028907	Dasypus novemcinctus	88.76	0.00e+00	1173.00
IUUC-Dor-030300	Dipodomys ordii	95.88	8.00e-169	587.00
IUUC-Dme-031580	Drosophila melanogaster	29.21	7.00e-39	155.00
IUUC-Ete-032641	Echinops telfairi	94.93	3.00e-130	459.00
IUUC-Eeu-035356	Erinaceus europaeus	88.92	0.00e+00	964.00
IUUC-Fca-036302	Felis catus	94.23	0.00e+00	1274.00
IUUC-Fal-036729	Ficedula albicollis	64.83	0.00e+00	1056.00
IUUC-Gga-040285	Gallus gallus	64.04	0.00e+00	1008.00
IUUC-Gac-041754	Gasterosteus aculeatus	27.73	2.00e-25	110.00
IUUC-Ggo-045534	Gorilla gorilla	92.15	0.00e+00	1322.00
IUUC-Hsa-046672	Homo sapiens	92.15	0.00e+00	1324.00
IUUC-Itr-048045	Ictidomys tridecemlineatus	91.86	0.00e+00	1303.00
IUUC-Lch-049837	Latimeria chalumnae	59.93	0.00e+00	920.00
IUUC-Loc-052010	Lepisosteus oculatus	54.99	0.00e+00	831.00
IUUC-Laf-053978	Loxodonta africana	91.39	0.00e+00	1241.00
IUUC-Mcc-055551	Macaca mulatta	91.80	0.00e+00	1321.00
IUUC-Meu-056006	Macropus eugenii	68.12	0.00e+00	954.00
IUUC-Mga-060136	Meleagris gallopavo	39.87	3.00e-149	522.00
IUUC-Mmr-061269	Microcebus murinus	90.63	0.00e+00	1342.00
IUUC-Mdo-062756	Monodelphis domestica	25.77	1.00e-38	154.00
IUUC-Mmu-063741	Mus musculus	90.57	0.00e+00	1316.00
IUUC-Mpu-066694	Mustela putorius furo	93.54	0.00e+00	1280.00
IUUC-Mlu-067377	Myotis lucifugus	92.39	0.00e+00	1292.00
IUUC-Nle-069243	Nomascus leucogenys	88.46	0.00e+00	681.00
IUUC-Opr-070611	Ochotona princeps	85.12	0.00e+00	1176.00
IUUC-Ont-071724	Oreochromis niloticus	52.37	0.00e+00	778.00
IUUC-Oan-073477	Ornithorhynchus anatinus	52.15	3.00e-47	180.00
IUUC-Ocu-074436	Oryctolagus cuniculus	81.20	0.00e+00	1105.00
IUUC-Ola-086487	Oryzias latipes	48.95	0.00e+00	722.00
IUUC-Oga-088966	Otolemur garnettii	92.19	0.00e+00	1376.00
IUUC-Oar-089394	Ovis aries	83.28	3.00e-136	479.00
IUUC-Ptr-090896	Pan troglodytes	92.26	0.00e+00	1355.00
IUUC-Pan-092021	Papio anubis	91.61	0.00e+00	1321.00
IUUC-Psi-094075	Pelodiscus sinensis	29.15	2.00e-72	267.00
IUUC-Pfo-097206	Poecilia formosa	27.35	2.00e-28	121.00
IUUC-Pab-098732	Pongo abelii	87.43	0.00e+00	1203.00
IUUC-Pca-100841	Procavia capensis	89.49	3.00e-178	619.00
IUUC-Pva-102291	Pteropus vampyrus	88.39	0.00e+00	924.00
IUUC-Rno-105602	Rattus norvegicus	91.50	0.00e+00	1335.00
IUUC-Sha-106605	Sarcophilus harrisii	62.32	1.00e-86	314.00
IUUC-Spo-108375	Schizosaccharomyces pombe	41.82	8.00e-08	53.50
IUUC-Ssc-116113	Sus scrofa	92.15	0.00e+00	1245.00
IUUC-Tgu-117420	Taeniopygia guttata	38.82	5.00e-144	504.00
IUUC-Tru-118044	Takifugu rubripes	46.43	3.00e-31	129.00
IUUC-Ttr-128533	Tursiops truncatus	92.35	0.00e+00	1256.00
IUUC-Xtr-132220	Xenopus tropicalis	31.57	7.00e-84	305.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence