iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000034758.12	ENSMUST00000142948.7	ENSMUSP00000117287.1
ENSMUSG00000034758.12	ENSMUST00000072020.8	ENSMUSP00000071905.2
ENSMUSG00000034758.12	ENSMUST00000151858.7	ENSMUSP00000119945.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-11	44.7	391	422

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd..tllvsGsdDgtikvWDlrtgvll 36
           c a+ ++  ++ ++G  Dgt+++WDlrt+  +
   Q: 391  CQALaNTkeNMALAGFTDGTVRIWDLRTQEIV 422
           5566733468999999************9876 PP

Organism

Mus musculus

Functional Description
(View)

As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.

Protein Sequence
(Fasta)

MTSHRQSSDT FGGILPSTLS SRYLSIVNQL PEEFSSVVSE MMVHLENIFS LAENFFQAIE 60
RFSRTPDLLE RNKMSIGVGA EGDSWPCHVS HEAPMGSAQT TENSAKEEDK QVPESAALQH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCGCCTTC TGATTGGTCA GGGCCTGCAG GGGCGGTTCG CTGAGTCCGG GGCCCACGTG 60
CACCGTGGCC TGGGCCCTGA TACACGCTTC CCTCGGTGGG TGCAGGGGGC GTGGTGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005938--C:cell cortex
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0050769--P:positive regulation of neurogenesis
GO:0045666--P:positive regulation of neuron differentiation

KEGG

mmu:114606

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002169	Ailuropoda melanoleuca	48.18	3.00e-103	369.00
IUUC-Bta-012704	Bos taurus	46.56	2.00e-103	369.00
IUUC-Cfa-020822	Canis familiaris	56.76	2.00e-88	318.00
IUUC-Cpo-021589	Cavia porcellus	49.56	2.00e-90	325.00
IUUC-Csa-023760	Chlorocebus sabaeus	49.89	1.00e-115	410.00
IUUC-Dno-029434	Dasypus novemcinctus	50.95	2.00e-44	173.00
IUUC-Dor-030782	Dipodomys ordii	52.44	2.00e-98	352.00
IUUC-Eca-033556	Equus caballus	57.49	6.00e-109	387.00
IUUC-Fca-035421	Felis catus	48.65	8.00e-108	384.00
IUUC-Ggo-044650	Gorilla gorilla	49.89	9.00e-115	407.00
IUUC-Hsa-046311	Homo sapiens	49.45	9.00e-114	404.00
IUUC-Itr-048864	Ictidomys tridecemlineatus	55.40	1.00e-62	232.00
IUUC-Laf-053971	Loxodonta africana	55.19	5.00e-91	327.00
IUUC-Mcc-055698	Macaca mulatta	49.89	3.00e-114	405.00
IUUC-Mmr-061647	Microcebus murinus	45.23	2.00e-119	422.00
IUUC-Mpu-066131	Mustela putorius furo	45.75	2.00e-109	389.00
IUUC-Mlu-068020	Myotis lucifugus	48.65	1.00e-110	393.00
IUUC-Oga-088838	Otolemur garnettii	59.66	2.00e-81	295.00
IUUC-Oar-090417	Ovis aries	46.05	3.00e-108	385.00
IUUC-Ptr-090523	Pan troglodytes	49.67	2.00e-104	372.00
IUUC-Pan-092275	Papio anubis	49.89	8.00e-114	404.00
IUUC-Pab-097952	Pongo abelii	54.93	3.00e-100	358.00
IUUC-Pva-102968	Pteropus vampyrus	48.86	8.00e-113	400.00
IUUC-Rno-105186	Rattus norvegicus	70.31	0.00e+00	803.00
IUUC-Ssc-116390	Sus scrofa	47.60	2.00e-106	379.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence