iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033482

UUCD1 version

UUC-EqC-01068

Ensembl Protein ID

ENSECAP00000000318.1

UniProt Accession

F7D469; F7D469_HORSE

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000000284.1	ENSECAT00000000410.1	ENSECAP00000000318.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.30e-59	200.0	4	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl+N+g tC +NS+LQ+L++   +++ l++    ++++ + +e+  ++  +l  l+e++++s++kav+p el  +l+k+++    + q
   Q: 4    VGLHNIGQTCCLNSLLQVLIMNVGFTKILKR---ITVPRGA-EEQRRSVPFQLLLLLEKMQDSRQKAVQPMELAYCLQKYKVP--LFVQ 86
           6******************************...5555443.567789*********************************98..79** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da  +   + + +++++                          ++    + ++ l+ +q+k++++cl+c  +ssr++++l+l+l++ +
   Q: 87   HDAAQLYLTVWNLIRDQI--------------------------TDVDLVQRLQALYTIQMKESLVCLDCTLESSRNSSMLTLPLSLFD 149
           ******************..........................567788999***********************************9 PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +++ +++l+d+L+ f+++ el ++ k++ce+c kk+  ++ l+l++lP++L++hL+Rfs   ++++ ek+  +++fp++Ldl++++ +
   Q: 150  MDSKPLKTLEDALRCFFQPRELSNKSKFFCEHCGKKTCRKQVLQLTHLPQTLTVHLMRFSI--RNMKTEKVCHSFYFPQSLDLNQVLLT 236
           99999******************************************************65..668999***************95555 PP
   S: 268  .peekqke...kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkr 337
            ++  ++e     +YeL+av+ H G ++ GHY+ay++n  +gkW++f+Ds+V  v++e+++ + g       + aY+l+Y++
   Q: 237  eQDLCDAEeqpGGQYELFAVIAHVGMAGFGHYCAYIRNsVDGKWFCFNDSNVCRVSWEDIQCTYGndnyrwgEIAYLLVYMK 318
           2333333344489*************************45677*******************888***************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

IGPVGLHNIG QTCCLNSLLQ VLIMNVGFTK ILKRITVPRG AEEQRRSVPF QLLLLLEKMQ 60
DSRQKAVQPM ELAYCLQKYK VPLFVQHDAA QLYLTVWNLI RDQITDVDLV QRLQALYTIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGGCCCGG TTGGTTTACA CAACATTGGA CAGACCTGCT GCCTTAACTC CCTGCTTCAG 60
GTATTGATCA TGAACGTGGG CTTCACCAAG ATATTGAAGC GGTAAGACTG TTATTCATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	87.91	2.00e-162	564.00
IUUC-Apl-004006	Anas platyrhynchos	56.92	3.00e-106	377.00
IUUC-Aca-005088	Anolis carolinensis	54.72	5.00e-93	334.00
IUUC-Ame-010606	Astyanax mexicanus	33.12	2.00e-40	159.00
IUUC-Bta-013036	Bos taurus	79.38	7.00e-154	536.00
IUUC-Cja-019052	Callithrix jacchus	73.60	2.00e-140	491.00
IUUC-Cfa-020554	Canis familiaris	87.19	5.00e-169	586.00
IUUC-Cpo-022421	Cavia porcellus	76.16	5.00e-144	503.00
IUUC-Csa-023737	Chlorocebus sabaeus	77.72	2.00e-95	341.00
IUUC-Cho-024807	Choloepus hoffmanni	70.05	1.00e-69	256.00
IUUC-Dre-027408	Danio rerio	34.71	1.00e-47	183.00
IUUC-Dno-029813	Dasypus novemcinctus	72.19	1.00e-120	425.00
IUUC-Dor-030532	Dipodomys ordii	77.74	3.00e-147	514.00
IUUC-Ete-032254	Echinops telfairi	74.69	2.00e-145	508.00
IUUC-Eeu-034451	Erinaceus europaeus	75.94	5.00e-96	343.00
IUUC-Fca-036313	Felis catus	86.56	5.00e-169	587.00
IUUC-Fal-037216	Ficedula albicollis	56.01	2.00e-101	362.00
IUUC-Gmo-038649	Gadus morhua	33.02	4.00e-39	154.00
IUUC-Gga-041082	Gallus gallus	55.38	8.00e-95	340.00
IUUC-Gac-042439	Gasterosteus aculeatus	35.65	3.00e-46	178.00
IUUC-Ggo-044957	Gorilla gorilla	81.99	1.00e-135	475.00
IUUC-Hsa-046381	Homo sapiens	81.50	3.00e-159	554.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	82.19	6.00e-155	540.00
IUUC-Loc-052688	Lepisosteus oculatus	32.61	2.00e-46	179.00
IUUC-Laf-054109	Loxodonta africana	82.81	1.00e-162	565.00
IUUC-Mcc-054814	Macaca mulatta	80.25	2.00e-158	551.00
IUUC-Meu-056253	Macropus eugenii	67.60	6.00e-108	383.00
IUUC-Mmr-061613	Microcebus murinus	79.38	1.00e-150	525.00
IUUC-Mdo-061890	Monodelphis domestica	66.36	8.00e-122	429.00
IUUC-Mmu-064329	Mus musculus	74.38	7.00e-135	473.00
IUUC-Mpu-066342	Mustela putorius furo	86.56	3.00e-167	580.00
IUUC-Mlu-067010	Myotis lucifugus	84.06	6.00e-163	566.00
IUUC-Nle-069148	Nomascus leucogenys	81.50	1.00e-158	552.00
IUUC-Opr-070988	Ochotona princeps	70.89	1.00e-63	236.00
IUUC-Ont-072039	Oreochromis niloticus	33.33	3.00e-45	175.00
IUUC-Oan-073740	Ornithorhynchus anatinus	56.99	3.00e-75	274.00
IUUC-Ocu-074498	Oryctolagus cuniculus	81.19	1.00e-146	512.00
IUUC-Ola-086753	Oryzias latipes	35.03	6.00e-46	177.00
IUUC-Oga-088497	Otolemur garnettii	82.35	5.00e-152	530.00
IUUC-Oar-089505	Ovis aries	78.82	3.00e-153	533.00
IUUC-Ptr-091656	Pan troglodytes	80.88	3.00e-158	551.00
IUUC-Pan-092498	Papio anubis	80.56	7.00e-159	553.00
IUUC-Psi-093409	Pelodiscus sinensis	55.05	1.00e-104	372.00
IUUC-Pfo-096507	Poecilia formosa	34.81	2.00e-45	176.00
IUUC-Pab-097828	Pongo abelii	81.68	4.00e-160	556.00
IUUC-Pca-100299	Procavia capensis	82.54	1.00e-89	323.00
IUUC-Pva-102972	Pteropus vampyrus	83.44	4.00e-160	557.00
IUUC-Rno-105738	Rattus norvegicus	71.56	2.00e-135	474.00
IUUC-Sha-107309	Sarcophilus harrisii	65.56	4.00e-115	407.00
IUUC-Sar-112983	Sorex araneus	76.66	4.00e-124	437.00
IUUC-Ssc-116049	Sus scrofa	81.93	6.00e-162	562.00
IUUC-Tgu-117115	Taeniopygia guttata	54.43	7.00e-101	360.00
IUUC-Tru-118022	Takifugu rubripes	30.62	1.00e-36	147.00
IUUC-Tsy-118986	Tarsius syrichta	86.29	8.00e-60	223.00
IUUC-Tni-120306	Tetraodon nigroviridis	30.57	9.00e-35	140.00
IUUC-Tbe-127768	Tupaia belangeri	74.69	5.00e-100	357.00
IUUC-Ttr-128686	Tursiops truncatus	80.31	9.00e-155	539.00
IUUC-Xtr-132032	Xenopus tropicalis	44.65	2.00e-71	261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence