iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089307

Ensembl Protein ID

ENSOARP00000007783.1

UniProt Accession

W5PBH2; W5PBH2_SHEEP

Genbank Protein ID

ENSOARP00000007783

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01099354

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007255.1	ENSOART00000007899.1	ENSOARP00000007783.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.60e-217	721.6	443	930

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++tv+D d +e+snlnrqFLfr+++++k+K+ +aa+a+ +
   Q: 443  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtgkekGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADAILK 531
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ +++ah ++++  +e i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 532  INPQLKIDAHLNKVCSATEAIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 620
           *********************9******************************************************************* PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+k+++ +++eg+++v  +l s++++++++++e+a+ +f+
   Q: 621  EIPFCTLKSFPAAIEHTIQWArdkfessfsykpSLFNKFWQTYPSAEEVLQKIQTGHSLEGCFQV-IKLLSRRPRSWSQCVELARLKFE 708
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f++
   Q: 709  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppsplkfdlneplhfsfllnaaklyatiycipfteedlsadillnilsevkiqEFKP 797
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l++++ ++ ++++++++++lsfekddd+  ++d++taa+nlra++++iep +d+ ++k+
   Q: 798  SDKVVQTDETARKPDHVPVSSEDernaiFQLEKAISSNEATTSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYSIEP-ADRLKTKR 885
           ****************998888899*******************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKv+   +fe++kn+fl++a+
   Q: 886  IAGRIIPAIATSTAAVSGLVALEMIKVAGDyPFEAYKNCFLNLAI 930
           *****************************************9886 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MEESQPEAAR PGEEASCSSW RTSRANTNFS SMPTESVEID DALYSRQRYV LGDTAMQKMA 60
KSHVFLSGMG GLGLEIAKNL VLAGIKALTI HDTEKCQAWD LGTNFFLCED DVVNIRNRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAAT CCCAGCCAGA GGCAGCACGT CCGGGGGAAG AGGCATCTTG CTCCTCCTGG 60
AGGACCAGCC GGTGAGAAAA AGAATGTGGG CGCGAAGTGA GGCATTGCGG GCAGGACCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

oas:101115278

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	93.06	0.00e+00	2045.00
IUUC-Apl-004158	Anas platyrhynchos	80.48	0.00e+00	1739.00
IUUC-Aca-005349	Anolis carolinensis	81.19	0.00e+00	1774.00
IUUC-Bta-012696	Bos taurus	98.20	0.00e+00	2158.00
IUUC-Cja-019563	Callithrix jacchus	91.63	0.00e+00	1991.00
IUUC-Cfa-020951	Canis familiaris	93.06	0.00e+00	2051.00
IUUC-Cpo-022307	Cavia porcellus	87.44	0.00e+00	1907.00
IUUC-Csa-023647	Chlorocebus sabaeus	92.02	0.00e+00	2001.00
IUUC-Cho-024682	Choloepus hoffmanni	77.25	0.00e+00	939.00
IUUC-Dre-028022	Danio rerio	67.06	0.00e+00	1471.00
IUUC-Dno-029796	Dasypus novemcinctus	91.14	0.00e+00	1947.00
IUUC-Dor-030981	Dipodomys ordii	75.40	0.00e+00	1508.00
IUUC-Ete-032514	Echinops telfairi	78.14	0.00e+00	1144.00
IUUC-Eca-033697	Equus caballus	93.38	0.00e+00	2017.00
IUUC-Eeu-035323	Erinaceus europaeus	84.54	0.00e+00	1366.00
IUUC-Fca-035858	Felis catus	94.55	0.00e+00	2038.00
IUUC-Fal-036848	Ficedula albicollis	80.41	0.00e+00	1730.00
IUUC-Gmo-039326	Gadus morhua	66.50	0.00e+00	1387.00
IUUC-Gga-040747	Gallus gallus	80.71	0.00e+00	1720.00
IUUC-Gac-041406	Gasterosteus aculeatus	66.86	0.00e+00	1392.00
IUUC-Ggo-044577	Gorilla gorilla	92.21	0.00e+00	2009.00
IUUC-Hsa-046007	Homo sapiens	92.21	0.00e+00	2003.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	93.07	0.00e+00	1048.00
IUUC-Lch-049992	Latimeria chalumnae	73.53	0.00e+00	1553.00
IUUC-Loc-051899	Lepisosteus oculatus	68.66	0.00e+00	1488.00
IUUC-Laf-054413	Loxodonta africana	92.51	0.00e+00	1873.00
IUUC-Mcc-054656	Macaca mulatta	92.30	0.00e+00	2005.00
IUUC-Meu-056463	Macropus eugenii	72.35	0.00e+00	1424.00
IUUC-Mga-059721	Meleagris gallopavo	78.91	0.00e+00	1627.00
IUUC-Mmr-060908	Microcebus murinus	88.50	0.00e+00	1940.00
IUUC-Mdo-062096	Monodelphis domestica	85.05	0.00e+00	1895.00
IUUC-Mmu-064114	Mus musculus	89.08	0.00e+00	1953.00
IUUC-Mpu-066017	Mustela putorius furo	92.68	0.00e+00	2051.00
IUUC-Mlu-068037	Myotis lucifugus	90.64	0.00e+00	1958.00
IUUC-Nle-069494	Nomascus leucogenys	91.83	0.00e+00	1996.00
IUUC-Opr-070910	Ochotona princeps	66.67	4.00e-172	598.00
IUUC-Ont-071592	Oreochromis niloticus	68.46	0.00e+00	1448.00
IUUC-Oan-073268	Ornithorhynchus anatinus	81.21	0.00e+00	1610.00
IUUC-Ocu-074296	Oryctolagus cuniculus	91.54	0.00e+00	2003.00
IUUC-Ola-086376	Oryzias latipes	68.66	0.00e+00	1404.00
IUUC-Oga-088186	Otolemur garnettii	90.68	0.00e+00	1978.00
IUUC-Ptr-090609	Pan troglodytes	92.40	0.00e+00	2002.00
IUUC-Pan-092905	Papio anubis	91.97	0.00e+00	1909.00
IUUC-Psi-093489	Pelodiscus sinensis	81.98	0.00e+00	1767.00
IUUC-Pma-094203	Petromyzon marinus	65.54	1.00e-56	211.00
IUUC-Pfo-096670	Poecilia formosa	68.69	0.00e+00	1465.00
IUUC-Pab-098418	Pongo abelii	92.21	0.00e+00	2003.00
IUUC-Pca-100889	Procavia capensis	75.29	0.00e+00	1592.00
IUUC-Pva-103144	Pteropus vampyrus	81.18	0.00e+00	1740.00
IUUC-Rno-105612	Rattus norvegicus	89.08	0.00e+00	1949.00
IUUC-Sha-107388	Sarcophilus harrisii	87.30	0.00e+00	1887.00
IUUC-Sar-113128	Sorex araneus	89.40	0.00e+00	1935.00
IUUC-Ssc-116117	Sus scrofa	94.59	0.00e+00	2079.00
IUUC-Tgu-116565	Taeniopygia guttata	81.00	0.00e+00	1746.00
IUUC-Tru-118591	Takifugu rubripes	67.61	0.00e+00	1426.00
IUUC-Tsy-119436	Tarsius syrichta	80.32	0.00e+00	1713.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.80	0.00e+00	1406.00
IUUC-Tbe-127714	Tupaia belangeri	78.76	0.00e+00	1387.00
IUUC-Ttr-129159	Tursiops truncatus	82.70	0.00e+00	1748.00
IUUC-Vpa-130716	Vicugna pacos	92.25	0.00e+00	1930.00
IUUC-Xtr-132947	Xenopus tropicalis	70.21	0.00e+00	1541.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence