iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036210

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02079729

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015756.3	ENSFCAT00000015760.3	ENSFCAP00000014613.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-65	220.7	105	480
ULD/UDP/UBQ/UBQ_Other	1.30e-09	37.9	5	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+++l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKDALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekge 191
           7******************************.****************************.99999******************999*9 PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+  ++ +++e+ +       ++a+  +++k+ksli++ F++++++++kc e +++ +++ + ++l
   Q: 192  qgQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDS-------SSASAVTPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQL 273
           999*********************6644444444433.......347788999************************999999888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 274  QLSCFINQEV--KYLFTGLKLRLQEEITK-----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 355
           8888877754..58999999999999998.....58899999999******************************************** PP
   S: 262  spfcts........................peekqke...........................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                         p     +                           +  Y+L av+ H+G s+ssGHYv++
   Q: 356  YELCTPelqekmvsfrskfkdledkkvnqqP-----KtsdkksspqkevkyepfsfaddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 439
           ******6666666666666666665555551.....0555556666677777777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 440  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 480
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           +vtvk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd ++++ ++k+g+t++++ +
   Q: 5    SVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDD-DWGNIKIKNGMTLLMMGS 74
           69********99*************************************999.9**************965 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MPLYSVTVKW GKEKFEGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKDDDWGN 60
IKIKNGMTLL MMGSADALPE EPSAKTVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCGCGCC CCCGCCTCTC CGGGCTTTCC ATCCAGTAGG CCCCGCCTCG CCGGCTCTGC 60
GCCGGGTCTT CTCCTGCAGT TGCCCTGTGG CTCCGTGGGC GGGTAAACTG CGTGTTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fca:101091976

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	31.18	1.00e-65	244.00
IUUC-Aml-002053	Ailuropoda melanoleuca	99.19	0.00e+00	941.00
IUUC-Atr-002725	Amborella trichopoda	42.03	2.00e-102	366.00
IUUC-Apl-004031	Anas platyrhynchos	91.46	0.00e+00	903.00
IUUC-Aca-004361	Anolis carolinensis	89.49	0.00e+00	918.00
IUUC-Aly-006078	Arabidopsis lyrata	42.20	1.00e-112	399.00
IUUC-Ath-007623	Arabidopsis thaliana	42.77	2.00e-113	402.00
IUUC-Ago-007796	Ashbya gossypii	32.43	5.00e-59	221.00
IUUC-Acl-008258	Aspergillus clavatus	37.19	3.00e-67	249.00
IUUC-Afl-008732	Aspergillus flavus	33.16	2.00e-79	290.00
IUUC-Afu-008755	Aspergillus fumigatus	35.29	8.00e-82	297.00
IUUC-Ani-009148	Aspergillus nidulans	38.88	2.00e-72	266.00
IUUC-Ang-009878	Aspergillus niger	37.99	3.00e-67	249.00
IUUC-Aor-010239	Aspergillus oryzae	33.16	1.00e-79	290.00
IUUC-Ate-010243	Aspergillus terreus	34.79	3.00e-79	289.00
IUUC-Ame-011327	Astyanax mexicanus	50.60	2.00e-128	452.00
IUUC-Bgr-012231	Blumeria graminis	34.33	7.00e-80	291.00
IUUC-Bta-012553	Bos taurus	98.18	0.00e+00	965.00
IUUC-Bci-013606	Botrytis cinerea	40.21	1.00e-70	260.00
IUUC-Bdi-014567	Brachypodium distachyon	44.33	5.00e-114	404.00
IUUC-Bol-016127	Brassica oleracea	42.80	5.00e-115	407.00
IUUC-Bra-017501	Brassica rapa	42.60	3.00e-114	405.00
IUUC-Cel-018140	Caenorhabditis elegans	42.38	1.00e-101	363.00
IUUC-Cja-019516	Callithrix jacchus	98.39	0.00e+00	962.00
IUUC-Cfa-020808	Canis familiaris	99.80	0.00e+00	979.00
IUUC-Cpo-021688	Cavia porcellus	97.57	0.00e+00	950.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.83	1.00e-83	303.00
IUUC-Csa-023429	Chlorocebus sabaeus	99.19	0.00e+00	945.00
IUUC-Cho-024347	Choloepus hoffmanni	98.38	0.00e+00	968.00
IUUC-Cin-025198	Ciona intestinalis	54.18	5.00e-153	534.00
IUUC-Csv-026007	Ciona savignyi	53.41	8.00e-155	540.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	38.70	3.00e-64	239.00
IUUC-Cne-026963	Cryptococcus neoformans	34.68	5.00e-76	278.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.81	6.00e-60	224.00
IUUC-Dre-027647	Danio rerio	82.45	0.00e+00	835.00
IUUC-Dno-029967	Dasypus novemcinctus	98.38	0.00e+00	942.00
IUUC-Dor-030886	Dipodomys ordii	92.50	0.00e+00	766.00
IUUC-Dse-031466	Dothistroma septosporum	36.10	8.00e-58	218.00
IUUC-Dme-032079	Drosophila melanogaster	55.35	2.00e-160	558.00
IUUC-Ete-032351	Echinops telfairi	86.64	0.00e+00	866.00
IUUC-Eca-033461	Equus caballus	98.38	0.00e+00	1009.00
IUUC-Eeu-035220	Erinaceus europaeus	74.39	0.00e+00	699.00
IUUC-Fal-037528	Ficedula albicollis	91.08	0.00e+00	884.00
IUUC-Fox-037805	Fusarium oxysporum	39.90	4.00e-71	262.00
IUUC-Fso-038177	Fusarium solani	38.34	2.00e-68	253.00
IUUC-Gmo-038953	Gadus morhua	77.80	0.00e+00	773.00
IUUC-Ggr-039972	Gaeumannomyces graminis	33.39	2.00e-74	273.00
IUUC-Gga-040462	Gallus gallus	90.49	0.00e+00	894.00
IUUC-Gac-041312	Gasterosteus aculeatus	82.14	0.00e+00	808.00
IUUC-Gma-043255	Glycine max	43.23	3.00e-110	391.00
IUUC-Ggo-045458	Gorilla gorilla	82.42	0.00e+00	797.00
IUUC-Hsa-045706	Homo sapiens	99.39	0.00e+00	948.00
IUUC-Hvu-047821	Hordeum vulgare	46.76	9.00e-58	216.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	98.18	0.00e+00	962.00
IUUC-Lch-050464	Latimeria chalumnae	82.86	0.00e+00	831.00
IUUC-Lpe-051419	Leersia perrieri	43.12	2.00e-109	389.00
IUUC-Loc-052732	Lepisosteus oculatus	81.45	0.00e+00	850.00
IUUC-Lma-053177	Leptosphaeria maculans	41.54	1.00e-71	263.00
IUUC-Laf-053822	Loxodonta africana	98.58	0.00e+00	967.00
IUUC-Mcc-055893	Macaca mulatta	99.39	0.00e+00	946.00
IUUC-Meu-056307	Macropus eugenii	82.86	0.00e+00	802.00
IUUC-Mor-057171	Magnaporthe oryzae	38.12	4.00e-68	252.00
IUUC-Mpo-057415	Magnaporthe poae	39.34	1.00e-70	260.00
IUUC-Mtr-057901	Medicago truncatula	43.20	2.00e-112	399.00
IUUC-Mla-058897	Melampsora laricipopulina	39.63	1.00e-75	277.00
IUUC-Mga-060016	Meleagris gallopavo	91.06	0.00e+00	900.00
IUUC-Mvi-060562	Microbotryum violaceum	39.84	4.00e-68	252.00
IUUC-Mmr-060624	Microcebus murinus	98.18	0.00e+00	1012.00
IUUC-Mdo-061809	Monodelphis domestica	93.35	0.00e+00	907.00
IUUC-Mmu-063869	Mus musculus	96.96	0.00e+00	951.00
IUUC-Mac-064876	Musa acuminata	39.72	9.00e-97	347.00
IUUC-Mpu-066480	Mustela putorius furo	99.39	0.00e+00	976.00
IUUC-Mlu-067866	Myotis lucifugus	97.98	0.00e+00	974.00
IUUC-Nfi-068393	Neosartorya fischeri	37.03	2.00e-67	249.00
IUUC-Ncr-068815	Neurospora crassa	36.02	3.00e-82	298.00
IUUC-Nle-070121	Nomascus leucogenys	99.60	7.00e-142	496.00
IUUC-Opr-070712	Ochotona princeps	77.62	5.00e-176	610.00
IUUC-Ont-071544	Oreochromis niloticus	82.08	0.00e+00	774.00
IUUC-Oan-073635	Ornithorhynchus anatinus	92.06	0.00e+00	757.00
IUUC-Ocu-074926	Oryctolagus cuniculus	96.96	0.00e+00	934.00
IUUC-Oba-075633	Oryza barthii	42.18	2.00e-109	388.00
IUUC-Obr-076423	Oryza brachyantha	43.03	3.00e-112	398.00
IUUC-Ogl-077913	Oryza glaberrima	42.22	7.00e-112	397.00
IUUC-Ogu-078435	Oryza glumaepatula	42.18	2.00e-109	388.00
IUUC-Oin-080072	Oryza indica	42.15	1.00e-109	389.00
IUUC-Olo-080535	Oryza longistaminata	39.40	5.00e-94	337.00
IUUC-Ome-081309	Oryza meridionalis	42.18	2.00e-109	388.00
IUUC-Oni-083113	Oryza nivara	42.18	2.00e-109	388.00
IUUC-Opu-083168	Oryza punctata	41.24	7.00e-104	370.00
IUUC-Oru-084253	Oryza rufipogon	42.18	2.00e-109	388.00
IUUC-Osa-085554	Oryza sativa	42.22	7.00e-112	397.00
IUUC-Ola-086998	Oryzias latipes	81.14	0.00e+00	798.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.29	2.00e-71	263.00
IUUC-Oga-088571	Otolemur garnettii	98.38	0.00e+00	963.00
IUUC-Oar-089526	Ovis aries	97.97	0.00e+00	960.00
IUUC-Ptr-091433	Pan troglodytes	99.39	0.00e+00	946.00
IUUC-Pan-091966	Papio anubis	99.19	0.00e+00	945.00
IUUC-Psi-093458	Pelodiscus sinensis	89.44	0.00e+00	857.00
IUUC-Pma-094343	Petromyzon marinus	68.86	6.00e-122	429.00
IUUC-Pno-095109	Phaeosphaeria nodorum	39.65	2.00e-66	246.00
IUUC-Ppa-095756	Physcomitrella patens	43.90	3.00e-113	401.00
IUUC-Pfo-096514	Poecilia formosa	82.48	0.00e+00	789.00
IUUC-Pab-098477	Pongo abelii	86.81	0.00e+00	747.00
IUUC-Pop-099221	Populus trichocarpa	41.77	1.00e-104	373.00
IUUC-Pca-100791	Procavia capensis	81.35	0.00e+00	632.00
IUUC-Ppe-101812	Prunus persica	41.77	6.00e-108	384.00
IUUC-Pva-102462	Pteropus vampyrus	93.94	0.00e+00	786.00
IUUC-Pgr-103623	Puccinia graminis	40.69	4.00e-75	275.00
IUUC-Ptt-103767	Puccinia triticina	39.70	2.00e-68	253.00
IUUC-Pte-104109	Pyrenophora teres	39.70	3.00e-71	262.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.31	2.00e-71	263.00
IUUC-Rno-105351	Rattus norvegicus	96.76	0.00e+00	907.00
IUUC-Sce-106168	Saccharomyces cerevisiae	33.00	5.00e-63	235.00
IUUC-Sha-107491	Sarcophilus harrisii	93.33	0.00e+00	925.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	33.73	1.00e-78	286.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.63	5.00e-81	295.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	35.45	4.00e-85	308.00
IUUC-Smo-108805	Selaginella moellendorffii	43.67	6.00e-111	394.00
IUUC-Sit-110361	Setaria italica	42.94	3.00e-115	408.00
IUUC-Sly-110965	Solanum lycopersicum	41.33	3.00e-109	388.00
IUUC-Sar-113355	Sorex araneus	84.85	0.00e+00	668.00
IUUC-Sbi-114778	Sorghum bicolor	44.24	2.00e-115	409.00
IUUC-Sre-115011	Sporisorium reilianum	36.62	1.00e-62	233.00
IUUC-Ssc-116273	Sus scrofa	98.17	0.00e+00	952.00
IUUC-Tgu-117063	Taeniopygia guttata	90.45	0.00e+00	881.00
IUUC-Tru-118381	Takifugu rubripes	79.47	0.00e+00	799.00
IUUC-Tsy-119076	Tarsius syrichta	82.90	4.00e-119	421.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.30	0.00e+00	791.00
IUUC-Tca-121246	Theobroma cacao	41.68	1.00e-109	389.00
IUUC-Tre-121969	Trichoderma reesei	34.66	2.00e-75	276.00
IUUC-Tvi-122543	Trichoderma virens	35.04	2.00e-78	286.00
IUUC-Tae-125484	Triticum aestivum	42.86	8.00e-111	393.00
IUUC-Tur-126128	Triticum urartu	33.27	2.00e-68	253.00
IUUC-Tbe-128030	Tupaia belangeri	91.39	0.00e+00	867.00
IUUC-Ttr-128701	Tursiops truncatus	97.41	0.00e+00	781.00
IUUC-Uma-129657	Ustilago maydis	37.08	2.00e-65	243.00
IUUC-Vda-129723	Verticillium dahliae	32.65	2.00e-71	263.00
IUUC-Vpa-130284	Vicugna pacos	70.90	0.00e+00	647.00
IUUC-Vvi-131037	Vitis vinifera	43.20	2.00e-109	389.00
IUUC-Xtr-132235	Xenopus tropicalis	85.89	0.00e+00	885.00
IUUC-Xma-133840	Xiphophorus maculatus	82.48	0.00e+00	814.00
IUUC-Yli-134453	Yarrowia lipolytica	36.98	7.00e-83	300.00
IUUC-Zma-135669	Zea mays	36.85	7.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence