iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Post-translational Modifications (PTMs)
dbPPT	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-30	105.3	391	423
UBD/Beta-Prp	2.00e-59	202.1	303	495

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +v+c+ + +d  ll++G+dD+++kvW++ +g++
   Q: 391  DVNCVTYsPDsQLLATGADDNKVKVWNVMSGTC 423
           79******999*****************99987 PP

UBD/Beta-Prp

   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfd 189
            +++v+++++++  d +v+G +  +  +++++   c++ +ls+ ++  +++v+++ g  l + +++ +++ +Wd +t++ + + +g h  +v++++++
   Q: 303  ASAKVTACDYHQGLDMVVVGFSNGVFGLYQMPDFICIH-LLSISRQKLTTAVFNERGnWLTFGCAKLGQLLVWDWRTETYILKQQG-HYFDVNCVTYS 398
           6789********88************************.******************6666777788*****************99.*********** PP
   S: 190  sngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsed 286
           ++++ l++g++d++vk+w++ +g+c  t+++ht+ v+ ++f  +++ l+s+s Dg++r Wd +  ++ kt++ +  +   + + ++++ v+++g+ d
   Q: 399  PDSQLLATGADDNKVKVWNVMSGTCFITFTEHTNAVTALHFMADNHSLLSASLDGTVRAWDFKRYKNYKTYTTPTPRQFVSLTADPSGDVVCAGTLD 495
           *************************************************************************995555555559999999999876 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MEFRFENLLG APYRGGNAVI TKNTQLISPV GNRVSVTDLS KNHSVTLPLE TSTNICRLAS 60
SPDGTFLLAV DEQNRCLFIN LPRRVVLHRI TFKDKVGALK FSPNGKFIAV GIGKLVEIWR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAATCCAGT TCATAACAGA AACCCTCGTT AAACCTAACG CCGTAATTAT CGCCTCCGGC 60
ATATCAATCC TCCGCCTTCT CATTCTTCTC CAGACGCCAT GGAGTTCCGT TTCGAGAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027145--PWP2
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005730--C:nucleolus
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0009553--P:embryo sac development
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000028--P:ribosomal small subunit assembly
GO:0006364--P:rRNA processing

KEGG

ath:AT1G15440

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	38.83	0.00e+00	674.00
IUUC-Atr-003033	Amborella trichopoda	61.04	0.00e+00	1093.00
IUUC-Apl-003219	Anas platyrhynchos	39.76	0.00e+00	684.00
IUUC-Aca-004950	Anolis carolinensis	40.90	0.00e+00	694.00
IUUC-Aly-006213	Arabidopsis lyrata	93.78	0.00e+00	1692.00
IUUC-Ago-007916	Ashbya gossypii	43.28	2.00e-147	515.00
IUUC-Acl-008225	Aspergillus clavatus	41.62	0.00e+00	717.00
IUUC-Afl-008390	Aspergillus flavus	41.53	0.00e+00	724.00
IUUC-Afu-009039	Aspergillus fumigatus	41.54	0.00e+00	714.00
IUUC-Ani-009228	Aspergillus nidulans	39.06	4.00e-177	614.00
IUUC-Ang-009663	Aspergillus niger	41.20	0.00e+00	697.00
IUUC-Aor-009923	Aspergillus oryzae	41.53	0.00e+00	724.00
IUUC-Ate-010264	Aspergillus terreus	42.12	0.00e+00	729.00
IUUC-Ame-010790	Astyanax mexicanus	33.10	5.00e-65	241.00
IUUC-Bgr-012066	Blumeria graminis	41.63	0.00e+00	712.00
IUUC-Bta-012399	Bos taurus	40.51	0.00e+00	674.00
IUUC-Bci-013757	Botrytis cinerea	46.23	3.00e-155	541.00
IUUC-Bdi-015028	Brachypodium distachyon	64.77	0.00e+00	1144.00
IUUC-Bol-016521	Brassica oleracea	86.89	0.00e+00	1540.00
IUUC-Bra-017096	Brassica rapa	87.22	0.00e+00	1539.00
IUUC-Cel-018690	Caenorhabditis elegans	31.54	1.00e-136	479.00
IUUC-Cja-019229	Callithrix jacchus	40.38	0.00e+00	687.00
IUUC-Cfa-020504	Canis familiaris	39.44	0.00e+00	672.00
IUUC-Cpo-021574	Cavia porcellus	40.31	0.00e+00	703.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	48.21	3.00e-178	618.00
IUUC-Csa-023436	Chlorocebus sabaeus	40.18	0.00e+00	676.00
IUUC-Cin-025397	Ciona intestinalis	39.19	8.00e-153	533.00
IUUC-Csv-026194	Ciona savignyi	42.96	3.00e-132	465.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	44.46	3.00e-149	521.00
IUUC-Cne-027031	Cryptococcus neoformans	41.83	0.00e+00	736.00
IUUC-Cme-027276	Cyanidioschyzon merolae	31.81	7.00e-107	381.00
IUUC-Dre-027514	Danio rerio	39.67	0.00e+00	670.00
IUUC-Dno-029191	Dasypus novemcinctus	40.07	9.00e-176	609.00
IUUC-Dor-030149	Dipodomys ordii	39.45	0.00e+00	688.00
IUUC-Dse-031260	Dothistroma septosporum	44.21	3.00e-141	494.00
IUUC-Dme-032043	Drosophila melanogaster	36.56	2.00e-167	582.00
IUUC-Ete-033102	Echinops telfairi	45.74	2.00e-147	515.00
IUUC-Eca-033223	Equus caballus	40.42	0.00e+00	694.00
IUUC-Fca-035795	Felis catus	38.60	0.00e+00	633.00
IUUC-Fal-036830	Ficedula albicollis	39.51	0.00e+00	675.00
IUUC-Fox-037835	Fusarium oxysporum	44.63	5.00e-151	528.00
IUUC-Fso-038324	Fusarium solani	44.63	6.00e-153	534.00
IUUC-Gmo-039355	Gadus morhua	38.91	0.00e+00	663.00
IUUC-Ggr-039840	Gaeumannomyces graminis	44.26	2.00e-141	496.00
IUUC-Gga-040907	Gallus gallus	45.83	2.00e-148	518.00
IUUC-Gac-042624	Gasterosteus aculeatus	39.11	0.00e+00	658.00
IUUC-Gma-043034	Glycine max	70.09	0.00e+00	1325.00
IUUC-Hsa-046327	Homo sapiens	39.96	0.00e+00	693.00
IUUC-Hvu-047416	Hordeum vulgare	65.44	0.00e+00	1160.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	40.88	0.00e+00	703.00
IUUC-Kpa-049150	Komagataella pastoris	39.54	0.00e+00	634.00
IUUC-Lch-049460	Latimeria chalumnae	37.70	1.00e-165	576.00
IUUC-Lpe-050840	Leersia perrieri	65.96	0.00e+00	1155.00
IUUC-Loc-052733	Lepisosteus oculatus	38.84	0.00e+00	669.00
IUUC-Lma-053277	Leptosphaeria maculans	45.47	4.00e-161	561.00
IUUC-Laf-054294	Loxodonta africana	40.20	0.00e+00	669.00
IUUC-Mcc-054624	Macaca mulatta	39.96	0.00e+00	695.00
IUUC-Meu-056665	Macropus eugenii	41.69	2.00e-91	329.00
IUUC-Mor-057288	Magnaporthe oryzae	44.19	2.00e-151	529.00
IUUC-Mpo-057594	Magnaporthe poae	45.33	1.00e-141	496.00
IUUC-Mtr-058700	Medicago truncatula	71.60	0.00e+00	1345.00
IUUC-Mla-058846	Melampsora laricipopulina	40.70	0.00e+00	666.00
IUUC-Mga-059207	Meleagris gallopavo	35.60	3.00e-168	585.00
IUUC-Mvi-060327	Microbotryum violaceum	42.95	0.00e+00	748.00
IUUC-Mmr-061264	Microcebus murinus	40.40	0.00e+00	665.00
IUUC-Mdo-062327	Monodelphis domestica	40.33	0.00e+00	687.00
IUUC-Mmu-063542	Mus musculus	40.07	0.00e+00	671.00
IUUC-Mac-065142	Musa acuminata	66.03	0.00e+00	1202.00
IUUC-Mpu-066098	Mustela putorius furo	38.86	2.00e-171	595.00
IUUC-Mlu-067056	Myotis lucifugus	36.37	6.00e-163	567.00
IUUC-Nfi-068323	Neosartorya fischeri	41.41	0.00e+00	718.00
IUUC-Ncr-068925	Neurospora crassa	39.98	0.00e+00	685.00
IUUC-Nle-068970	Nomascus leucogenys	39.96	0.00e+00	691.00
IUUC-Opr-070966	Ochotona princeps	50.32	5.00e-100	357.00
IUUC-Ont-071252	Oreochromis niloticus	39.25	0.00e+00	667.00
IUUC-Oan-072737	Ornithorhynchus anatinus	39.23	0.00e+00	660.00
IUUC-Oba-075794	Oryza barthii	64.19	0.00e+00	1140.00
IUUC-Obr-076617	Oryza brachyantha	65.55	0.00e+00	1176.00
IUUC-Ogl-077022	Oryza glaberrima	65.56	0.00e+00	1183.00
IUUC-Ogu-078757	Oryza glumaepatula	53.94	0.00e+00	879.00
IUUC-Oin-079813	Oryza indica	65.41	0.00e+00	1179.00
IUUC-Olo-080265	Oryza longistaminata	65.74	0.00e+00	1179.00
IUUC-Ome-081494	Oryza meridionalis	65.63	0.00e+00	1178.00
IUUC-Oni-082639	Oryza nivara	54.05	0.00e+00	879.00
IUUC-Opu-084005	Oryza punctata	66.52	0.00e+00	1191.00
IUUC-Oru-084883	Oryza rufipogon	53.61	0.00e+00	878.00
IUUC-Osa-086158	Oryza sativa	65.63	0.00e+00	1176.00
IUUC-Ola-086822	Oryzias latipes	44.39	3.00e-157	548.00
IUUC-Olu-087741	Ostreococcus lucimarinus	32.80	3.00e-21	93.20
IUUC-Oga-088887	Otolemur garnettii	39.65	0.00e+00	670.00
IUUC-Oar-090110	Ovis aries	39.93	0.00e+00	642.00
IUUC-Pan-092808	Papio anubis	40.64	0.00e+00	703.00
IUUC-Psi-093954	Pelodiscus sinensis	40.13	0.00e+00	692.00
IUUC-Pno-094922	Phaeosphaeria nodorum	45.14	2.00e-162	565.00
IUUC-Ppa-095678	Physcomitrella patens	55.57	0.00e+00	940.00
IUUC-Pfo-097175	Poecilia formosa	39.98	0.00e+00	687.00
IUUC-Pab-098155	Pongo abelii	40.09	0.00e+00	692.00
IUUC-Pop-099635	Populus trichocarpa	73.58	0.00e+00	1342.00
IUUC-Pca-100947	Procavia capensis	38.35	0.00e+00	642.00
IUUC-Ppe-101552	Prunus persica	74.39	0.00e+00	1394.00
IUUC-Pva-102744	Pteropus vampyrus	36.94	3.00e-167	581.00
IUUC-Pgr-103389	Puccinia graminis	45.89	6.00e-159	554.00
IUUC-Ptt-103953	Puccinia triticina	44.77	4.00e-120	425.00
IUUC-Pte-104079	Pyrenophora teres	45.68	1.00e-160	559.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	45.68	2.00e-160	558.00
IUUC-Rno-105502	Rattus norvegicus	39.45	0.00e+00	689.00
IUUC-Sce-106390	Saccharomyces cerevisiae	40.11	0.00e+00	682.00
IUUC-Sha-107264	Sarcophilus harrisii	41.28	5.00e-91	327.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	39.46	0.00e+00	685.00
IUUC-Spo-108348	Schizosaccharomyces pombe	41.57	0.00e+00	701.00
IUUC-Smo-108982	Selaginella moellendorffii	57.25	0.00e+00	1030.00
IUUC-Sit-110304	Setaria italica	65.22	0.00e+00	1203.00
IUUC-Sly-111620	Solanum lycopersicum	76.62	0.00e+00	920.00
IUUC-Stu-112877	Solanum tuberosum	70.60	0.00e+00	1330.00
IUUC-Sbi-114702	Sorghum bicolor	65.33	0.00e+00	1190.00
IUUC-Sre-115129	Sporisorium reilianum	41.61	0.00e+00	674.00
IUUC-Ssc-115931	Sus scrofa	43.40	1.00e-93	335.00
IUUC-Tgu-116787	Taeniopygia guttata	38.42	0.00e+00	676.00
IUUC-Tru-118218	Takifugu rubripes	39.54	0.00e+00	677.00
IUUC-Tsy-119401	Tarsius syrichta	44.06	1.00e-117	417.00
IUUC-Tni-120046	Tetraodon nigroviridis	39.09	0.00e+00	631.00
IUUC-Tca-121685	Theobroma cacao	72.41	0.00e+00	1365.00
IUUC-Tre-122154	Trichoderma reesei	40.86	0.00e+00	696.00
IUUC-Tvi-122451	Trichoderma virens	44.52	8.00e-159	553.00
IUUC-Tae-125397	Triticum aestivum	73.03	0.00e+00	711.00
IUUC-Tur-126650	Triticum urartu	66.42	0.00e+00	1082.00
IUUC-Tme-127005	Tuber melanosporum	47.41	1.00e-162	566.00
IUUC-Tbe-128102	Tupaia belangeri	38.57	3.00e-115	409.00
IUUC-Ttr-128259	Tursiops truncatus	40.45	0.00e+00	668.00
IUUC-Uma-129511	Ustilago maydis	42.38	0.00e+00	689.00
IUUC-Vda-129833	Verticillium dahliae	40.07	3.00e-133	468.00
IUUC-Vvi-131572	Vitis vinifera	69.12	0.00e+00	1276.00
IUUC-Xtr-131776	Xenopus tropicalis	35.10	3.00e-62	232.00
IUUC-Xma-133887	Xiphophorus maculatus	39.65	0.00e+00	668.00
IUUC-Yli-134427	Yarrowia lipolytica	46.13	4.00e-160	558.00
IUUC-Zma-135980	Zea mays	64.22	0.00e+00	1142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence