iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107246

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01229022

Gene Name

MID2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013756.1	ENSSHAT00000016296.1	ENSSHAP00000016162.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.20e-07	30.3	26	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw......pglknssskefrCPlCr 46
           C+iCle f+d pl+lpC H  +++C +++       g + +   +f+CP+Cr
   Q: 26   CPICLELFED-PLLLPCAHSLCFSCAHRIlvsncsSGESVEPIAAFQCPTCR 76
           **********.999************999777777666666677779****8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

PASMVLNGPT RLFSLKMETL ESELTCPICL ELFEDPLLLP CAHSLCFSCA HRILVSNCSS 60
GESVEPIAAF QCPTCRYVIS LTHRGLDGLK RNVTLQNIID RFQKASLSGP NSPGESCRER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTGCTTA GGGAATTCTT ACTAAGCTCT CCTTTGTATT ACAGGTGAAT GACCAGCCTC 60
CATGGTTCTT AATGGACCAA CAAGATTATT TTCATTAAAG ATGGAAACAT TGGAGTCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR033491--MID2
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50853--FN3
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00041--fn3
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00502--BBC
SM00336--BBOX
SM00060--FN3
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005874--C:microtubule
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0035372--P:protein localization to microtubule

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001342	Ailuropoda melanoleuca	90.01	0.00e+00	1380.00
IUUC-Apl-004167	Anas platyrhynchos	87.02	0.00e+00	1286.00
IUUC-Cja-019379	Callithrix jacchus	90.07	0.00e+00	1353.00
IUUC-Cfa-021219	Canis familiaris	94.01	0.00e+00	1368.00
IUUC-Cpo-021954	Cavia porcellus	93.59	0.00e+00	1365.00
IUUC-Csa-023047	Chlorocebus sabaeus	93.58	0.00e+00	1394.00
IUUC-Cho-025087	Choloepus hoffmanni	79.27	0.00e+00	685.00
IUUC-Dre-028003	Danio rerio	79.39	0.00e+00	1173.00
IUUC-Dno-029344	Dasypus novemcinctus	93.72	0.00e+00	1367.00
IUUC-Ete-032883	Echinops telfairi	82.59	0.00e+00	1227.00
IUUC-Eca-033688	Equus caballus	94.60	0.00e+00	1378.00
IUUC-Eeu-034882	Erinaceus europaeus	80.06	0.00e+00	1183.00
IUUC-Fca-036427	Felis catus	89.88	0.00e+00	1377.00
IUUC-Fal-036967	Ficedula albicollis	80.03	0.00e+00	1085.00
IUUC-Gmo-038518	Gadus morhua	72.08	0.00e+00	841.00
IUUC-Gga-040408	Gallus gallus	87.02	0.00e+00	1325.00
IUUC-Gac-041617	Gasterosteus aculeatus	77.38	0.00e+00	1165.00
IUUC-Ggo-045217	Gorilla gorilla	89.74	0.00e+00	1374.00
IUUC-Hsa-045969	Homo sapiens	89.60	0.00e+00	1374.00
IUUC-Itr-049079	Ictidomys tridecemlineatus	90.49	0.00e+00	1357.00
IUUC-Lch-050468	Latimeria chalumnae	80.64	0.00e+00	1174.00
IUUC-Laf-054029	Loxodonta africana	90.21	0.00e+00	1353.00
IUUC-Mcc-055424	Macaca mulatta	89.88	0.00e+00	1377.00
IUUC-Meu-056432	Macropus eugenii	94.79	0.00e+00	1278.00
IUUC-Mga-059599	Meleagris gallopavo	85.65	0.00e+00	1188.00
IUUC-Mmr-061432	Microcebus murinus	88.92	0.00e+00	1365.00
IUUC-Mdo-061989	Monodelphis domestica	99.57	0.00e+00	1455.00
IUUC-Mmu-063963	Mus musculus	90.21	0.00e+00	1352.00
IUUC-Mpu-065964	Mustela putorius furo	93.87	0.00e+00	1398.00
IUUC-Mlu-067148	Myotis lucifugus	93.72	0.00e+00	1396.00
IUUC-Nle-069552	Nomascus leucogenys	93.58	0.00e+00	1392.00
IUUC-Opr-070968	Ochotona princeps	94.14	7.00e-153	534.00
IUUC-Ont-072260	Oreochromis niloticus	73.60	0.00e+00	1171.00
IUUC-Ocu-074109	Oryctolagus cuniculus	93.30	0.00e+00	1392.00
IUUC-Oga-089063	Otolemur garnettii	90.21	0.00e+00	1354.00
IUUC-Oar-089845	Ovis aries	93.87	0.00e+00	1396.00
IUUC-Ptr-091360	Pan troglodytes	89.60	0.00e+00	1374.00
IUUC-Pan-092900	Papio anubis	89.37	0.00e+00	1368.00
IUUC-Pfo-096044	Poecilia formosa	79.83	0.00e+00	1010.00
IUUC-Pab-098637	Pongo abelii	93.71	0.00e+00	1392.00
IUUC-Pva-102319	Pteropus vampyrus	88.81	0.00e+00	1322.00
IUUC-Rno-105496	Rattus norvegicus	93.44	0.00e+00	1391.00
IUUC-Ssc-115858	Sus scrofa	93.72	0.00e+00	1394.00
IUUC-Tru-118237	Takifugu rubripes	79.00	0.00e+00	1182.00
IUUC-Tsy-119383	Tarsius syrichta	90.01	0.00e+00	1304.00
IUUC-Tni-119919	Tetraodon nigroviridis	78.04	0.00e+00	1182.00
IUUC-Ttr-128902	Tursiops truncatus	90.63	0.00e+00	1357.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence