iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061925

UUCD1 version

UUC-MoD-01138

Ensembl Protein ID

ENSMODP00000004672.3

UniProt Accession

F6YW83; F6YW83_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000003814.3	ENSMODT00000004772.3	ENSMODP00000004672.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.30e-80	268.6	1881	2233

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +GlkN g+tCYmN+v Q+L++ p l e ll+     ++++  ++p+ ++  ++q+lf +l++sk +++ p++++k++k++++e+   
   Q: 1881 VGLKNGGATCYMNAVFQQLYMQPGLPESLLS-----VDDD-MDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVR 1961
           6******************************.....5544.368999**************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           eqqDa Ef++ l+dq++e+l                          kk   +++ +++Fqg +++q +c++c ++++ree f+ l+l
   Q: 1962 EQQDAYEFFTSLIDQMDEYL--------------------------KKIGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNL 2022
           ********************..........................678899*********************************** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
            v + +     sl+ +L++f++ e leg+n+yycekck+k++++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ fp +L++
   Q: 2023 GVTSCQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNM 2104
           ******.....9*************************************************************************** PP
   S: 262  spfcts.........................peekqkekkkYeLiavvvHsGslssGHYvayvkn....ekgkWllfdDskVtevk. 318
           +p+++s                         p +k++ +++YeL++v+vHsG+++ GHY++++k+     kgkW++f+D+ V+e + 
   Q: 2105 EPYTVSgmarqdsscdvgengrhvdagsggsPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDrrgcGKGKWYKFNDTVVEEFEl 2191
           ******77777777777666666666666666666666***************************55555666************84 PP
   S: 319  eeevleetg.......................staYvlfYkr 337
            +e le +                        ++aY+lfY+r
   Q: 2192 NDETLEYECfggeyrpkvydqsnpypdvrrryWNAYMLFYQR 2233
           4666664449******************************98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEVGRQWVHS GLICGGGNAP SAYGGDRSIN ALLLSRQGHV TGALCDGALV SSYSLPAPPR 60
PSPEGAPSGS GAGRRATWPR SAAPDLRALR QPRPEQPQPR PRSGPAAGAA APVGHARHAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACTCCATG GAGGTAGGGC GCCAATGGGT GCACAGCGGG TTAATCTGTG GGGGTGGGAA 60
CGCTCCCTCC GCCTATGGGG GGGACCGGAG CATCAATGCC CTCCTCCTGT CCCGGCAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	94.31	0.00e+00	4647.00
IUUC-Apl-003203	Anas platyrhynchos	74.95	0.00e+00	3520.00
IUUC-Aca-004396	Anolis carolinensis	91.04	0.00e+00	4468.00
IUUC-Ate-010246	Aspergillus terreus	24.65	2.00e-52	202.00
IUUC-Ame-011886	Astyanax mexicanus	85.00	0.00e+00	1777.00
IUUC-Bta-013381	Bos taurus	94.27	0.00e+00	4630.00
IUUC-Cel-018352	Caenorhabditis elegans	30.46	1.00e-64	243.00
IUUC-Cja-018955	Callithrix jacchus	94.01	0.00e+00	4261.00
IUUC-Cfa-020720	Canis familiaris	94.26	0.00e+00	4637.00
IUUC-Cpo-022430	Cavia porcellus	92.94	0.00e+00	3313.00
IUUC-Csa-024180	Chlorocebus sabaeus	94.38	0.00e+00	4476.00
IUUC-Cho-025074	Choloepus hoffmanni	89.75	0.00e+00	1796.00
IUUC-Dre-027696	Danio rerio	81.29	0.00e+00	4029.00
IUUC-Dno-029307	Dasypus novemcinctus	91.69	0.00e+00	4506.00
IUUC-Dor-030889	Dipodomys ordii	90.92	0.00e+00	4432.00
IUUC-Ete-032294	Echinops telfairi	86.84	0.00e+00	2229.00
IUUC-Eca-033823	Equus caballus	89.23	0.00e+00	4345.00
IUUC-Eeu-035178	Erinaceus europaeus	83.32	0.00e+00	2029.00
IUUC-Fca-035444	Felis catus	94.25	0.00e+00	4590.00
IUUC-Fal-037555	Ficedula albicollis	92.73	0.00e+00	4530.00
IUUC-Gmo-038587	Gadus morhua	79.75	0.00e+00	2488.00
IUUC-Gga-041231	Gallus gallus	92.90	0.00e+00	4572.00
IUUC-Gac-041584	Gasterosteus aculeatus	80.00	0.00e+00	2457.00
IUUC-Ggo-044502	Gorilla gorilla	94.27	0.00e+00	4624.00
IUUC-Hsa-045851	Homo sapiens	94.23	0.00e+00	4620.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	94.88	0.00e+00	1518.00
IUUC-Lch-049999	Latimeria chalumnae	79.66	0.00e+00	3824.00
IUUC-Loc-051767	Lepisosteus oculatus	82.00	0.00e+00	4123.00
IUUC-Laf-054139	Loxodonta africana	93.87	0.00e+00	4607.00
IUUC-Mcc-055217	Macaca mulatta	94.23	0.00e+00	4620.00
IUUC-Meu-056659	Macropus eugenii	84.34	0.00e+00	2307.00
IUUC-Mga-059267	Meleagris gallopavo	92.82	0.00e+00	4567.00
IUUC-Mmr-060971	Microcebus murinus	93.18	0.00e+00	4586.00
IUUC-Mmu-064019	Mus musculus	93.75	0.00e+00	4662.00
IUUC-Mpu-066652	Mustela putorius furo	94.23	0.00e+00	4655.00
IUUC-Mlu-067518	Myotis lucifugus	94.13	0.00e+00	4588.00
IUUC-Nle-069763	Nomascus leucogenys	94.05	0.00e+00	4590.00
IUUC-Opr-071031	Ochotona princeps	87.66	0.00e+00	4244.00
IUUC-Ont-072136	Oreochromis niloticus	78.74	0.00e+00	3904.00
IUUC-Oan-072908	Ornithorhynchus anatinus	84.31	0.00e+00	983.00
IUUC-Ocu-073880	Oryctolagus cuniculus	93.48	0.00e+00	4618.00
IUUC-Ola-086544	Oryzias latipes	77.64	0.00e+00	3753.00
IUUC-Oga-088695	Otolemur garnettii	94.23	0.00e+00	4653.00
IUUC-Oar-089401	Ovis aries	94.17	0.00e+00	4590.00
IUUC-Ptr-091657	Pan troglodytes	94.22	0.00e+00	4614.00
IUUC-Pan-092394	Papio anubis	94.27	0.00e+00	4622.00
IUUC-Psi-093813	Pelodiscus sinensis	93.22	0.00e+00	4549.00
IUUC-Pma-094698	Petromyzon marinus	52.55	2.00e-137	482.00
IUUC-Pfo-096811	Poecilia formosa	78.32	0.00e+00	3959.00
IUUC-Pab-097814	Pongo abelii	94.15	0.00e+00	4616.00
IUUC-Pca-101135	Procavia capensis	90.24	0.00e+00	2151.00
IUUC-Pva-102334	Pteropus vampyrus	90.97	0.00e+00	4405.00
IUUC-Rno-105040	Rattus norvegicus	93.75	0.00e+00	4637.00
IUUC-Sha-106658	Sarcophilus harrisii	98.10	0.00e+00	4794.00
IUUC-Sar-113153	Sorex araneus	81.73	0.00e+00	2640.00
IUUC-Ssc-115641	Sus scrofa	92.57	0.00e+00	4430.00
IUUC-Tgu-117467	Taeniopygia guttata	93.93	0.00e+00	3323.00
IUUC-Tru-118074	Takifugu rubripes	71.67	0.00e+00	3443.00
IUUC-Tsy-119165	Tarsius syrichta	92.73	0.00e+00	2257.00
IUUC-Tni-119923	Tetraodon nigroviridis	68.40	0.00e+00	3221.00
IUUC-Tbe-127910	Tupaia belangeri	83.98	0.00e+00	1741.00
IUUC-Ttr-128218	Tursiops truncatus	93.18	0.00e+00	4593.00
IUUC-Vpa-130090	Vicugna pacos	92.68	0.00e+00	1660.00
IUUC-Xtr-131911	Xenopus tropicalis	85.90	0.00e+00	1731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence