iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088171

Ensembl Protein ID

ENSOGAP00000001651.2

UniProt Accession

H0WJH3; H0WJH3_OTOGA

Genbank Protein ID

ENSOGAP00000001651

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03089501

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000001849.2	ENSOGAT00000001855.2	ENSOGAP00000001651.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-30	102.3	1531	1565
UBD/Beta-Prp	5.00e-42	144.1	1398	1602

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1531 HKDWVCALAFvPGrPMLLSACRAGVIKVWNVDNFT 1565
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirv.....wdletgqcl 129
            e +++++ +sp+g +++ +++ +++++w+ls ++++ +l+gh   v++l++ +  s+ d +v+Gs+d ++++     + + t    
   Q: 1398 GEHQINQIALSPSG-TMLYAASGNAVRIWELSRFQPIAKLTGHIGPVMCLTVTQtaSRhDLVVTGSKDHYVKMfklgdYVTGTIGPT 1483
           5678*********9.999************************************98555**************44444444444455 PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           ++++ +h + + c+++++  ++l+sGs D+ ++ Wdl +++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + + + 
   Q: 1484 HNFEPPHYDGIECLSIQG--DILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGVIKVWNVDNFTPIG 1568
           55***************9..**************************999************************************** PP
   S: 217  tlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
           + +gh+++++ + +   ++++ ++ssD ++++W +r
   Q: 1569 EIKGHDSPINAICTN--TKHIFTASSDLTVKFWSVR 1602
           **********87777..****************876 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

RIRPQLSKEK IEGCHICTSV TPGEPQVLLG KDKAFTYDFV FDLDTWQEQI YSTCVNKLIE 60
GCFEGYNATV LAYGQTGAGK TYTMGTGFDM ATSEEEQGII PRAIAHLFGG IAERKRRAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATCCGGC CTCAACTATC GAAGGAGAAG ATTGAGGGCT GTCACATCTG CACCTCTGTT 60
ACCCCGGGAG AACCCCAGGT CCTGCTGGGG AAGGACAAGG CCTTCACCTA TGACTTTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	94.72	0.00e+00	2778.00
IUUC-Apl-003204	Anas platyrhynchos	76.67	0.00e+00	1585.00
IUUC-Aca-004506	Anolis carolinensis	79.66	0.00e+00	1546.00
IUUC-Ame-011515	Astyanax mexicanus	73.12	0.00e+00	1381.00
IUUC-Bta-013185	Bos taurus	75.06	0.00e+00	2079.00
IUUC-Cja-018844	Callithrix jacchus	92.65	0.00e+00	2722.00
IUUC-Cfa-021187	Canis familiaris	95.00	0.00e+00	2742.00
IUUC-Cpo-022444	Cavia porcellus	92.65	0.00e+00	2739.00
IUUC-Csa-023852	Chlorocebus sabaeus	95.32	0.00e+00	2770.00
IUUC-Csv-026158	Ciona savignyi	54.75	3.00e-179	622.00
IUUC-Dre-027839	Danio rerio	73.51	0.00e+00	1418.00
IUUC-Dno-030058	Dasypus novemcinctus	91.02	0.00e+00	2727.00
IUUC-Dor-030673	Dipodomys ordii	90.14	0.00e+00	2555.00
IUUC-Ete-032705	Echinops telfairi	82.40	0.00e+00	876.00
IUUC-Eca-033885	Equus caballus	93.32	0.00e+00	2694.00
IUUC-Eeu-035338	Erinaceus europaeus	80.20	0.00e+00	2145.00
IUUC-Fca-035388	Felis catus	94.73	0.00e+00	2578.00
IUUC-Fal-037044	Ficedula albicollis	86.07	0.00e+00	2615.00
IUUC-Gmo-039034	Gadus morhua	65.73	0.00e+00	1194.00
IUUC-Gac-041328	Gasterosteus aculeatus	71.38	0.00e+00	2204.00
IUUC-Ggo-045392	Gorilla gorilla	94.97	0.00e+00	2753.00
IUUC-Hsa-046713	Homo sapiens	95.57	0.00e+00	2773.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	94.35	0.00e+00	1597.00
IUUC-Loc-052703	Lepisosteus oculatus	77.86	0.00e+00	2391.00
IUUC-Laf-054193	Loxodonta africana	85.64	0.00e+00	2484.00
IUUC-Mcc-055484	Macaca mulatta	94.38	0.00e+00	2748.00
IUUC-Meu-056278	Macropus eugenii	87.48	0.00e+00	1185.00
IUUC-Mga-059816	Meleagris gallopavo	83.73	0.00e+00	2528.00
IUUC-Mmr-061071	Microcebus murinus	92.91	0.00e+00	2731.00
IUUC-Mdo-062845	Monodelphis domestica	89.53	0.00e+00	2668.00
IUUC-Mmu-063967	Mus musculus	93.70	0.00e+00	2688.00
IUUC-Mpu-066448	Mustela putorius furo	93.25	0.00e+00	2731.00
IUUC-Nle-070037	Nomascus leucogenys	93.61	0.00e+00	2125.00
IUUC-Opr-070325	Ochotona princeps	89.38	0.00e+00	2547.00
IUUC-Ont-071851	Oreochromis niloticus	71.44	0.00e+00	2210.00
IUUC-Oan-073615	Ornithorhynchus anatinus	86.79	0.00e+00	2446.00
IUUC-Ocu-073855	Oryctolagus cuniculus	93.45	0.00e+00	2692.00
IUUC-Ola-086703	Oryzias latipes	70.76	0.00e+00	2201.00
IUUC-Oar-089693	Ovis aries	76.46	0.00e+00	1147.00
IUUC-Ptr-090535	Pan troglodytes	93.91	0.00e+00	1726.00
IUUC-Pan-091917	Papio anubis	95.28	0.00e+00	2598.00
IUUC-Psi-093752	Pelodiscus sinensis	76.05	0.00e+00	1332.00
IUUC-Pfo-096827	Poecilia formosa	68.29	0.00e+00	1340.00
IUUC-Pab-098441	Pongo abelii	95.44	0.00e+00	2783.00
IUUC-Pca-100781	Procavia capensis	95.81	0.00e+00	903.00
IUUC-Pva-103099	Pteropus vampyrus	89.01	0.00e+00	1321.00
IUUC-Rno-105872	Rattus norvegicus	92.70	0.00e+00	2729.00
IUUC-Sha-107097	Sarcophilus harrisii	88.47	0.00e+00	2629.00
IUUC-Ssc-115638	Sus scrofa	92.99	0.00e+00	2425.00
IUUC-Tgu-116504	Taeniopygia guttata	87.14	0.00e+00	1690.00
IUUC-Tru-118242	Takifugu rubripes	71.70	0.00e+00	2217.00
IUUC-Ttr-128824	Tursiops truncatus	87.26	0.00e+00	2145.00
IUUC-Xtr-131798	Xenopus tropicalis	64.16	0.00e+00	1158.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence