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Tag Content
UUCD2 ID IUUC-Itr-048303
UUCD1 version UUC-SpT-00107
Ensembl Protein ID ENSSTOP00000012342.2
UniProt Accession I3MLN3; I3MLN3_ICTTR
Genbank Protein ID ENSSTOP00000012342
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AGTP01045339
Gene Name KMT2C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000013723.2 ENSSTOT00000013772.2 ENSSTOP00000012342.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.20e-32 111.0 1038 1089
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
           +C+vC +++++e+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1038 SCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADigFDCSMCR 1089
           6********************************999999998899******8 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MSLFLSRPRS RGKTTVDDED SMDGLETTEA ENIVETEVKE QSAEEDAEAE VDSSKQPASA 60
LQRSMSEDSA NSLVSVGVEA KISEQLCAFC YCGEKSSLGQ GDLKQFRVTP GFILPWKNQT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-048303|E3,PHD|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TATCTACTCT GTCCAGAACC TATTAAGTTG TTGAAGCTAC TCCTGTAGAC AAAGGGAGTC 60
TCCAGAAGGT TATCTGGAAA GAGGAAAGGC CAGAATAGGG ATACCTCGGC CAGTTTTAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-048303|E3,PHD|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002314 Ailuropoda melanoleuca 85.18 0.00e+00 7060.00
IUUC-Apl-003311 Anas platyrhynchos 71.71 0.00e+00 5721.00
IUUC-Aca-004705 Anolis carolinensis 66.14 0.00e+00 5330.00
IUUC-Bta-012322 Bos taurus 81.82 0.00e+00 6626.00
IUUC-Cel-018354 Caenorhabditis elegans 35.67 1.00e-64 243.00
IUUC-Cja-019983 Callithrix jacchus 86.92 0.00e+00 7434.00
IUUC-Cfa-020903 Canis familiaris 84.29 0.00e+00 7180.00
IUUC-Cpo-021732 Cavia porcellus 84.11 0.00e+00 7107.00
IUUC-Csa-023083 Chlorocebus sabaeus 85.14 0.00e+00 5522.00
IUUC-Cho-024469 Choloepus hoffmanni 79.37 0.00e+00 2195.00
IUUC-Dre-028110 Danio rerio 63.89 0.00e+00 1247.00
IUUC-Dor-030569 Dipodomys ordii 81.38 0.00e+00 4611.00
IUUC-Dme-031590 Drosophila melanogaster 33.60 2.00e-69 258.00
IUUC-Eca-033945 Equus caballus 84.96 0.00e+00 5153.00
IUUC-Fca-035922 Felis catus 83.58 0.00e+00 6879.00
IUUC-Gac-041896 Gasterosteus aculeatus 48.75 0.00e+00 1357.00
IUUC-Ggo-044812 Gorilla gorilla 84.90 0.00e+00 7228.00
IUUC-Hsa-046595 Homo sapiens 87.45 0.00e+00 7454.00
IUUC-Lch-050086 Latimeria chalumnae 56.73 0.00e+00 2642.00
IUUC-Loc-052891 Lepisosteus oculatus 50.33 0.00e+00 2085.00
IUUC-Laf-054348 Loxodonta africana 81.50 0.00e+00 3027.00
IUUC-Mcc-054868 Macaca mulatta 87.59 0.00e+00 7393.00
IUUC-Meu-056322 Macropus eugenii 66.81 0.00e+00 1202.00
IUUC-Mga-059541 Meleagris gallopavo 71.50 0.00e+00 5638.00
IUUC-Mmr-061092 Microcebus murinus 84.79 0.00e+00 5534.00
IUUC-Mdo-062610 Monodelphis domestica 74.78 0.00e+00 2075.00
IUUC-Mmu-063666 Mus musculus 84.88 0.00e+00 7105.00
IUUC-Mpu-066366 Mustela putorius furo 83.14 0.00e+00 6555.00
IUUC-Mlu-068201 Myotis lucifugus 80.87 0.00e+00 4162.00
IUUC-Nle-069232 Nomascus leucogenys 84.61 0.00e+00 5486.00
IUUC-Opr-070625 Ochotona princeps 76.25 0.00e+00 1307.00
IUUC-Ont-072401 Oreochromis niloticus 56.76 0.00e+00 1050.00
IUUC-Oan-072945 Ornithorhynchus anatinus 71.16 0.00e+00 4186.00
IUUC-Ocu-074920 Oryctolagus cuniculus 82.47 0.00e+00 5361.00
IUUC-Ola-086436 Oryzias latipes 43.98 0.00e+00 1831.00
IUUC-Oga-088637 Otolemur garnettii 82.20 0.00e+00 4352.00
IUUC-Oar-089363 Ovis aries 79.78 0.00e+00 6465.00
IUUC-Ptr-091527 Pan troglodytes 87.49 0.00e+00 7510.00
IUUC-Pan-092102 Papio anubis 85.05 0.00e+00 7105.00
IUUC-Pma-094252 Petromyzon marinus 39.07 0.00e+00 635.00
IUUC-Pfo-096288 Poecilia formosa 47.63 0.00e+00 1472.00
IUUC-Pab-098241 Pongo abelii 86.58 0.00e+00 4778.00
IUUC-Pca-100103 Procavia capensis 79.86 0.00e+00 1562.00
IUUC-Pva-102238 Pteropus vampyrus 76.23 0.00e+00 2562.00
IUUC-Rno-105395 Rattus norvegicus 75.44 0.00e+00 1128.00
IUUC-Sha-106550 Sarcophilus harrisii 71.98 0.00e+00 4430.00
IUUC-Sar-113183 Sorex araneus 65.78 0.00e+00 682.00
IUUC-Tgu-116677 Taeniopygia guttata 71.12 0.00e+00 5390.00
IUUC-Tru-118037 Takifugu rubripes 47.30 0.00e+00 1463.00
IUUC-Tsy-118932 Tarsius syrichta 86.29 0.00e+00 5270.00
IUUC-Tni-119970 Tetraodon nigroviridis 47.21 0.00e+00 1405.00
IUUC-Ttr-129051 Tursiops truncatus 82.66 0.00e+00 6584.00
IUUC-Vpa-130236 Vicugna pacos 80.50 0.00e+00 1889.00
Created Date 25-Jun-2017

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