iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033946

UUCD1 version

UUC-EqC-01004

Ensembl Protein ID

ENSECAP00000017121.1

UniProt Accession

F7DF20; F7DF20_HORSE

Protein Name

Uncharacterized protein

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019449.1	ENSECAT00000020830.1	ENSECAP00000017121.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.70e-37	129.0	184	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al+  + + +++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 184  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKALYALMEKGAEKEALKRRWRWQQTQQNKesglvytedewQKEWNELIKLASSEprmh 272
           6899********************************************************************************98887 PP
   S: 75   ...akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYd 133
                g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++
   Q: 273  lgtN-GancggvesseepvyeslEEFHVFVLAHVLRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPASQcHRSPLVLAYDQAHFS 360
           7650.255579****************************************************************************** PP
   S: 134  aLval 138
           aLv++
   Q: 361  ALVSM 365
           **986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MTLDMDAVLS DFVRSTGAEP GLARDLLEGK NWDVSAALSD FEQLRQVHAG NLPLPFSERS 60
GGSRTPEKGF SDRESTRLPR PTLQRQDDIV QEKRLSRGIS HASSSIVSLA RSHVSSNGGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTGGAGGC CTGACTTTTG ATCTATGTCC TCCCTACATC AGCTGTGTGA AAGTACTTAA 60
TGATCACATG ACCCTGGACA TGGATGCTGT CCTGTCGGAT TTTGTCCGTT CCACAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom

PROSITE

PS50802--OTU

Pfam

PF02338--OTU

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0070530--F:K63-linked polyubiquitin binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006955--P:immune response
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	95.65	0.00e+00	1091.00
IUUC-Apl-003567	Anas platyrhynchos	74.53	0.00e+00	866.00
IUUC-Bta-013398	Bos taurus	96.46	0.00e+00	1060.00
IUUC-Cel-018468	Caenorhabditis elegans	51.00	1.00e-86	313.00
IUUC-Cja-019965	Callithrix jacchus	95.01	0.00e+00	1114.00
IUUC-Cfa-020191	Canis familiaris	96.14	0.00e+00	1075.00
IUUC-Cpo-022232	Cavia porcellus	91.61	0.00e+00	964.00
IUUC-Csa-023593	Chlorocebus sabaeus	95.01	0.00e+00	1111.00
IUUC-Cho-024729	Choloepus hoffmanni	92.89	8.00e-129	454.00
IUUC-Csv-026177	Ciona savignyi	28.87	2.00e-03	35.40
IUUC-Dno-029900	Dasypus novemcinctus	94.85	0.00e+00	1046.00
IUUC-Dor-031121	Dipodomys ordii	85.15	0.00e+00	694.00
IUUC-Ete-032473	Echinops telfairi	88.89	0.00e+00	985.00
IUUC-Eeu-034670	Erinaceus europaeus	94.04	0.00e+00	1018.00
IUUC-Fca-035871	Felis catus	96.94	0.00e+00	1057.00
IUUC-Fso-038203	Fusarium solani	29.59	4.40e-02	33.50
IUUC-Gmo-039373	Gadus morhua	76.82	0.00e+00	684.00
IUUC-Gga-041105	Gallus gallus	76.36	0.00e+00	863.00
IUUC-Gac-041806	Gasterosteus aculeatus	67.93	0.00e+00	754.00
IUUC-Ggo-045472	Gorilla gorilla	95.49	0.00e+00	1070.00
IUUC-Hsa-046473	Homo sapiens	95.17	0.00e+00	1071.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	95.49	0.00e+00	1051.00
IUUC-Lch-050432	Latimeria chalumnae	75.24	0.00e+00	859.00
IUUC-Mcc-055261	Macaca mulatta	94.85	0.00e+00	1112.00
IUUC-Meu-056477	Macropus eugenii	82.15	0.00e+00	838.00
IUUC-Mga-059533	Meleagris gallopavo	77.71	0.00e+00	863.00
IUUC-Mdo-062847	Monodelphis domestica	87.94	0.00e+00	945.00
IUUC-Mmu-064260	Mus musculus	89.39	0.00e+00	969.00
IUUC-Mpu-066876	Mustela putorius furo	90.05	0.00e+00	988.00
IUUC-Mlu-068039	Myotis lucifugus	96.14	0.00e+00	1046.00
IUUC-Nle-069260	Nomascus leucogenys	94.85	0.00e+00	1063.00
IUUC-Opr-070564	Ochotona princeps	91.16	0.00e+00	788.00
IUUC-Ocu-073824	Oryctolagus cuniculus	94.17	0.00e+00	957.00
IUUC-Oga-088124	Otolemur garnettii	94.53	0.00e+00	1038.00
IUUC-Oar-090086	Ovis aries	97.26	0.00e+00	1064.00
IUUC-Ptr-091622	Pan troglodytes	95.01	0.00e+00	1074.00
IUUC-Pan-092724	Papio anubis	94.85	0.00e+00	1110.00
IUUC-Psi-093333	Pelodiscus sinensis	71.52	0.00e+00	813.00
IUUC-Pab-098667	Pongo abelii	95.17	0.00e+00	1061.00
IUUC-Pva-102136	Pteropus vampyrus	94.85	0.00e+00	1054.00
IUUC-Rno-105546	Rattus norvegicus	90.03	0.00e+00	986.00
IUUC-Sha-106732	Sarcophilus harrisii	86.36	0.00e+00	828.00
IUUC-Sar-113562	Sorex araneus	83.28	0.00e+00	857.00
IUUC-Ssc-116191	Sus scrofa	96.78	0.00e+00	1058.00
IUUC-Tsy-119343	Tarsius syrichta	89.86	0.00e+00	995.00
IUUC-Tbe-127283	Tupaia belangeri	94.77	0.00e+00	777.00
IUUC-Ttr-128692	Tursiops truncatus	91.79	0.00e+00	944.00
IUUC-Xtr-132888	Xenopus tropicalis	70.00	0.00e+00	771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence