iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067672

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02011656

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006756.2	ENSMLUT00000006749.2	ENSMLUP00000006163.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.40e-88	294.7	46	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+  +l+     ++  +++++++ +++ +w +++  vsp+ l +al+++ + f +  
   Q: 46   TGLRNLGNTCYMNAILQCLCSISPLVEYFLSgKYITALH-----KDCSKVATAFAYVMTDMWLGDSDCVSPEILRSALGNLYPAFMKKT 129
           7******************************44444443.....56779**************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+lkk      ++ ++ + + +     +k   +++s++++lF+gql  +i+cl+c+n + r+e f+ l+lp+p
   Q: 130  QQDAQEFLIYVLNELHESLKK-----FHRRRSWE-TGSVPRCCRKAIASETSIVTRLFEGQLNYSIMCLKCENCTYRNEVFTVLPLPIP 212
           *******************55.....33333333.3344456789999***************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           ++ ++   slqdcL+ f+++++l+ +n+++c+ c+ kqea  + +++k P+++i+hLkRf  +  + +++k+ + +++pl+ Ldl+p+ 
   Q: 213  SEYKC---SLQDCLQCFFQQDTLTWNNQIHCSFCETKQEAAVRASISKAPKIMIFHLKRF--DILGTMKRKLRTDIHYPLTnLDLTPYI 296
           ****9...****************************************************..55668999******************* PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           +   +k   + kY+L+avv+H G l+sGHY+a++kn+  + W+ fdD++V+e++ ++v++   +taY+lfY 
   Q: 297  CPVFRK---HPKYNLCAVVNHFGDLDSGHYTAFCKNSVTQaWFSFDDTRVSEIPDTSVQT---ATAYLLFYS 362
           *95544...89*************************98888*******************...********6 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

FTNMTSQRPS PGDDFGIYYV LAECADHCRG SPVHPGGNQP HLQGVTGLRN LGNTCYMNAI 60
LQCLCSISPL VEYFLSGKYI TALHKDCSKV ATAFAYVMTD MWLGDSDCVS PEILRSALGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCACTAACA TGACTTCGCA GCGGCCTTCC CCCGGCGATG ACTTCGGCAT CTACTACGTC 60
CTGTGAGCCT CTGTCCACTG CGGCTTTCTC ACTTGGGGCG GGGCGGGAGC CCACGCTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	87.43	0.00e+00	687.00
IUUC-Aca-005256	Anolis carolinensis	47.55	2.00e-99	355.00
IUUC-Bta-012753	Bos taurus	82.09	0.00e+00	642.00
IUUC-Cfa-020054	Canis familiaris	84.75	2.00e-172	598.00
IUUC-Cpo-021375	Cavia porcellus	77.68	2.00e-162	565.00
IUUC-Csa-023902	Chlorocebus sabaeus	80.45	2.00e-101	361.00
IUUC-Cho-024755	Choloepus hoffmanni	71.30	2.00e-137	481.00
IUUC-Dor-030311	Dipodomys ordii	86.96	7.00e-95	340.00
IUUC-Ete-032570	Echinops telfairi	62.67	2.00e-101	362.00
IUUC-Eca-034343	Equus caballus	87.43	0.00e+00	686.00
IUUC-Eeu-034510	Erinaceus europaeus	84.33	5.00e-163	566.00
IUUC-Fca-035920	Felis catus	87.87	0.00e+00	684.00
IUUC-Fal-036903	Ficedula albicollis	57.59	2.00e-106	378.00
IUUC-Gac-042261	Gasterosteus aculeatus	44.21	7.00e-74	270.00
IUUC-Hsa-046665	Homo sapiens	78.72	9.00e-158	549.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	87.33	0.00e+00	686.00
IUUC-Lch-049925	Latimeria chalumnae	52.27	1.00e-106	379.00
IUUC-Loc-051880	Lepisosteus oculatus	49.85	2.00e-79	290.00
IUUC-Laf-054494	Loxodonta africana	85.83	0.00e+00	664.00
IUUC-Mcc-055507	Macaca mulatta	85.43	1.00e-179	622.00
IUUC-Meu-055906	Macropus eugenii	74.10	8.00e-148	516.00
IUUC-Mmr-061564	Microcebus murinus	62.43	8.00e-106	376.00
IUUC-Mdo-061800	Monodelphis domestica	76.37	3.00e-170	590.00
IUUC-Mmu-063618	Mus musculus	80.91	0.00e+00	632.00
IUUC-Mpu-066699	Mustela putorius furo	87.70	0.00e+00	692.00
IUUC-Opr-070949	Ochotona princeps	82.47	8.00e-151	526.00
IUUC-Ont-072200	Oreochromis niloticus	45.05	1.00e-67	250.00
IUUC-Oan-073725	Ornithorhynchus anatinus	64.15	3.00e-142	498.00
IUUC-Ocu-074021	Oryctolagus cuniculus	88.44	0.00e+00	692.00
IUUC-Oga-088258	Otolemur garnettii	85.76	1.00e-163	568.00
IUUC-Oar-089881	Ovis aries	84.22	0.00e+00	668.00
IUUC-Ptr-090988	Pan troglodytes	79.10	1.00e-153	535.00
IUUC-Pan-091773	Papio anubis	84.95	0.00e+00	655.00
IUUC-Psi-093243	Pelodiscus sinensis	72.06	2.00e-138	485.00
IUUC-Pab-097713	Pongo abelii	80.74	8.00e-171	592.00
IUUC-Pca-100226	Procavia capensis	65.38	3.00e-127	447.00
IUUC-Pva-103172	Pteropus vampyrus	86.09	2.00e-177	614.00
IUUC-Rno-105950	Rattus norvegicus	81.84	0.00e+00	636.00
IUUC-Sha-107026	Sarcophilus harrisii	76.64	1.00e-165	575.00
IUUC-Ssc-116383	Sus scrofa	88.77	0.00e+00	704.00
IUUC-Tgu-116511	Taeniopygia guttata	55.49	2.00e-99	355.00
IUUC-Tbe-127808	Tupaia belangeri	78.99	2.00e-58	219.00
IUUC-Ttr-129046	Tursiops truncatus	82.25	1.00e-166	578.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence