iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000009265.3	ENSMMUT00000012951.3	ENSMMUP00000012139.3
ENSMMUG00000009265.3	ENSMMUT00000012952.3	ENSMMUP00000012140.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-28	96.6	753	789
UBD/Beta-Prp	9.30e-58	196.9	657	915

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.fsdtllvsGsdDgtikvWDlrtgvll 36
           gHt+ + +l  +s+++++sGs D+t++ WDlr   ++
   Q: 753  GHTGHILALYtWSGWMIASGSQDKTVRFWDLRVPSCV 789
           89999***966977*****************988887 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgk....ilvtgse.Drtikvwdlstg 84
           ++hhk+ i+cv++sp ++llatgs d+ +kv  +  +++       ++s h+++++++ f +  +    il++++  D +i+  d + g
   Q: 657  NKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCnatgpDLEFSMHDGTIRDLAFMEGPEsggaILISAGAgDCNIYTTDCQRG 745
           68*****************************99999999889888899************987667778777765516788888***** PP
   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           + +h+l+gh+  +l+l     g  ++sGs+d+t+r wdl+  +c++    t+ g+ ++v +v+v+p+g+ll++G  D+ ++l+d++ g+
   Q: 746  QGLHALSGHTGHILALYTWS-GWMIASGSQDKTVRFWDLRVPSCVRVvgtTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGR 833
           **************997777.9***********************99999*************************************** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++     h ++v+s+ f++   +l++gs+d ++k+ dlq    ++  ++ + +h+d v + r + +d  ++s s+D+++ +W
   Q: 834  MVQSYHP-HSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQgdltKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 915
           *****98.********************************99977788*********************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MTAEETVNVK EVEIIKLILD FLNSKKLHIS MLALEKESGV INGLFSDDML FLRQLILDGQ 60
WDEVLQFIQP LECMEKFDKK RFRYIILKQK FLEALCVNNA MSAEDEPQHL EFTMQEAVQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTATCAATA TGACGGCTGA GGAAACAGTG AATGTAAAAG AGGTTGAAAT CATTAAGCTA 60
ATTTTGGACT TCCTGAATTC TAAGAAGCTT CACATTAGTA TGCTGGCCCT GGAGAAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR006595--CTLH_C
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001519	Ailuropoda melanoleuca	97.09	0.00e+00	1655.00
IUUC-Apl-003954	Anas platyrhynchos	91.44	0.00e+00	1555.00
IUUC-Aca-004766	Anolis carolinensis	89.36	0.00e+00	1489.00
IUUC-Ame-010725	Astyanax mexicanus	70.22	0.00e+00	1124.00
IUUC-Bta-013072	Bos taurus	95.66	0.00e+00	1608.00
IUUC-Cel-018667	Caenorhabditis elegans	48.63	1.00e-94	341.00
IUUC-Cja-018835	Callithrix jacchus	98.38	0.00e+00	1662.00
IUUC-Cfa-020380	Canis familiaris	94.89	0.00e+00	1007.00
IUUC-Cpo-021883	Cavia porcellus	96.09	0.00e+00	1587.00
IUUC-Csa-023467	Chlorocebus sabaeus	99.78	0.00e+00	1694.00
IUUC-Cho-024342	Choloepus hoffmanni	87.30	0.00e+00	1480.00
IUUC-Cin-025112	Ciona intestinalis	44.20	8.00e-73	266.00
IUUC-Dre-027530	Danio rerio	76.41	0.00e+00	1258.00
IUUC-Dno-029290	Dasypus novemcinctus	97.61	0.00e+00	1656.00
IUUC-Dor-030258	Dipodomys ordii	82.84	0.00e+00	1356.00
IUUC-Dme-032040	Drosophila melanogaster	52.42	3.00e-102	365.00
IUUC-Ete-032248	Echinops telfairi	90.50	0.00e+00	788.00
IUUC-Eca-033623	Equus caballus	97.83	0.00e+00	1655.00
IUUC-Fca-036425	Felis catus	95.98	0.00e+00	1471.00
IUUC-Fal-036661	Ficedula albicollis	90.77	0.00e+00	1531.00
IUUC-Gmo-039527	Gadus morhua	74.86	0.00e+00	1228.00
IUUC-Gga-041177	Gallus gallus	90.76	0.00e+00	1532.00
IUUC-Gac-042049	Gasterosteus aculeatus	74.13	0.00e+00	1236.00
IUUC-Ggo-044833	Gorilla gorilla	98.60	0.00e+00	1678.00
IUUC-Hsa-046084	Homo sapiens	98.60	0.00e+00	1679.00
IUUC-Lch-050313	Latimeria chalumnae	80.89	0.00e+00	1401.00
IUUC-Loc-051790	Lepisosteus oculatus	81.91	0.00e+00	1406.00
IUUC-Laf-053521	Loxodonta africana	96.63	0.00e+00	1625.00
IUUC-Meu-056734	Macropus eugenii	93.55	0.00e+00	689.00
IUUC-Mga-059381	Meleagris gallopavo	90.15	0.00e+00	1532.00
IUUC-Mmr-060859	Microcebus murinus	97.19	0.00e+00	1653.00
IUUC-Mdo-062501	Monodelphis domestica	91.99	0.00e+00	1456.00
IUUC-Mmu-063126	Mus musculus	95.33	0.00e+00	1596.00
IUUC-Mpu-066718	Mustela putorius furo	97.23	0.00e+00	1308.00
IUUC-Mlu-067246	Myotis lucifugus	96.52	0.00e+00	1632.00
IUUC-Nle-069807	Nomascus leucogenys	98.81	0.00e+00	1680.00
IUUC-Opr-070862	Ochotona princeps	87.37	8.00e-68	252.00
IUUC-Ont-072519	Oreochromis niloticus	75.89	0.00e+00	1253.00
IUUC-Oan-072740	Ornithorhynchus anatinus	89.62	0.00e+00	787.00
IUUC-Ocu-074898	Oryctolagus cuniculus	97.71	0.00e+00	1628.00
IUUC-Ola-086396	Oryzias latipes	76.12	0.00e+00	1290.00
IUUC-Oga-088563	Otolemur garnettii	96.98	0.00e+00	1644.00
IUUC-Oar-089926	Ovis aries	97.50	0.00e+00	1655.00
IUUC-Ptr-090706	Pan troglodytes	98.49	0.00e+00	1675.00
IUUC-Pan-091740	Papio anubis	99.89	0.00e+00	1696.00
IUUC-Psi-093938	Pelodiscus sinensis	90.61	0.00e+00	1541.00
IUUC-Pfo-096531	Poecilia formosa	76.62	0.00e+00	1253.00
IUUC-Pab-098312	Pongo abelii	99.35	0.00e+00	1689.00
IUUC-Pca-101100	Procavia capensis	90.27	0.00e+00	727.00
IUUC-Pva-102734	Pteropus vampyrus	86.58	0.00e+00	1197.00
IUUC-Rno-105625	Rattus norvegicus	95.22	0.00e+00	1559.00
IUUC-Sha-106999	Sarcophilus harrisii	90.47	0.00e+00	1508.00
IUUC-Sar-112988	Sorex araneus	85.14	0.00e+00	1187.00
IUUC-Ssc-115384	Sus scrofa	97.17	0.00e+00	1619.00
IUUC-Tgu-116808	Taeniopygia guttata	90.47	0.00e+00	1513.00
IUUC-Tru-118233	Takifugu rubripes	75.94	0.00e+00	1222.00
IUUC-Tsy-119509	Tarsius syrichta	99.20	0.00e+00	681.00
IUUC-Tni-120473	Tetraodon nigroviridis	74.07	0.00e+00	1246.00
IUUC-Tbe-127447	Tupaia belangeri	91.05	2.00e-146	513.00
IUUC-Ttr-128459	Tursiops truncatus	94.03	0.00e+00	1503.00
IUUC-Vpa-130258	Vicugna pacos	91.29	0.00e+00	1007.00
IUUC-Xtr-132609	Xenopus tropicalis	79.31	0.00e+00	1314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence