iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116421

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU468504

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000010187.2	ENSSSCT00000011153.2	ENSSSCP00000010864.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.30e-41	136.3	508	544
UBD/Beta-Prp	1.90e-68	231.1	271	565

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHtd +t+l f +d  l++s+s D++++vWD+r  ++
   Q: 508  GHTDNITSLTFsPDsSLIASASMDNSVRVWDIRNTHC 544
           8***********999****************987665 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +sp+++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 271  LNTAEISPESKLLAAGFDNSCIKLWSLRSKKLkpephrvdvsrihlacdileeeddedddvgteMKVLRGHCGPVYSTRFLADSSGLLS 359
           5667889********************************************************9999********************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v+++++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDNITSLTFSPDSSLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvavlsfgd 277
           +Wd+r+  +   + ++ s ++ v + ++++
   Q: 536  VWDIRNTHCSAPTDGSSSELVGVYTGQMSN 565
           *********999999997777777644443 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYGDADGPLK QGLRLSQSAE EMAANLAVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SAKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGTAG CTATTCTGTG GATTGTGCCA TGCTCTTCCA AGGTTTTGTA TAGATAATAA 60
TTTTTCTGAG CCTTAAAATA GTATTGAAAT AAGAATCAAT TATTTGTGGC TTTTTGAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	95.76	0.00e+00	1086.00
IUUC-Apl-003636	Anas platyrhynchos	90.19	0.00e+00	1093.00
IUUC-Aca-004229	Anolis carolinensis	89.98	0.00e+00	1064.00
IUUC-Ame-010599	Astyanax mexicanus	67.05	0.00e+00	815.00
IUUC-Bta-013404	Bos taurus	93.72	0.00e+00	1058.00
IUUC-Cja-019643	Callithrix jacchus	95.42	0.00e+00	1089.00
IUUC-Cfa-020913	Canis familiaris	95.59	0.00e+00	1088.00
IUUC-Cpo-021777	Cavia porcellus	92.36	0.00e+00	1058.00
IUUC-Csa-024184	Chlorocebus sabaeus	95.08	0.00e+00	1088.00
IUUC-Cho-024638	Choloepus hoffmanni	94.57	0.00e+00	1074.00
IUUC-Cin-025618	Ciona intestinalis	34.62	1.00e-88	320.00
IUUC-Csv-025874	Ciona savignyi	34.54	2.00e-88	319.00
IUUC-Dre-028817	Danio rerio	67.61	0.00e+00	807.00
IUUC-Dno-029969	Dasypus novemcinctus	88.46	0.00e+00	1025.00
IUUC-Dor-031117	Dipodomys ordii	93.21	0.00e+00	1091.00
IUUC-Ete-032712	Echinops telfairi	87.27	0.00e+00	972.00
IUUC-Eca-033742	Equus caballus	95.59	0.00e+00	1088.00
IUUC-Eeu-035096	Erinaceus europaeus	93.05	0.00e+00	1095.00
IUUC-Fca-035769	Felis catus	94.75	0.00e+00	1102.00
IUUC-Fal-036645	Ficedula albicollis	89.75	0.00e+00	1028.00
IUUC-Gmo-038636	Gadus morhua	63.83	0.00e+00	768.00
IUUC-Gga-040144	Gallus gallus	90.15	0.00e+00	1065.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.56	0.00e+00	811.00
IUUC-Ggo-044568	Gorilla gorilla	95.25	0.00e+00	1088.00
IUUC-Hsa-046178	Homo sapiens	95.25	0.00e+00	1088.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	89.64	0.00e+00	1065.00
IUUC-Lch-050501	Latimeria chalumnae	76.95	0.00e+00	858.00
IUUC-Loc-052895	Lepisosteus oculatus	82.83	0.00e+00	642.00
IUUC-Laf-053950	Loxodonta africana	91.51	0.00e+00	1058.00
IUUC-Mcc-055450	Macaca mulatta	95.08	0.00e+00	1085.00
IUUC-Meu-056182	Macropus eugenii	86.25	0.00e+00	999.00
IUUC-Mga-059619	Meleagris gallopavo	90.32	0.00e+00	1069.00
IUUC-Mmr-061074	Microcebus murinus	93.57	0.00e+00	1096.00
IUUC-Mdo-062307	Monodelphis domestica	91.25	0.00e+00	880.00
IUUC-Mmu-063226	Mus musculus	91.00	0.00e+00	1031.00
IUUC-Mpu-066016	Mustela putorius furo	95.59	0.00e+00	1087.00
IUUC-Mlu-067257	Myotis lucifugus	87.48	0.00e+00	1063.00
IUUC-Nle-070139	Nomascus leucogenys	95.08	0.00e+00	1086.00
IUUC-Opr-070243	Ochotona princeps	89.81	0.00e+00	1059.00
IUUC-Ont-072686	Oreochromis niloticus	68.67	0.00e+00	828.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.10	0.00e+00	826.00
IUUC-Ocu-074525	Oryctolagus cuniculus	94.40	0.00e+00	1104.00
IUUC-Ola-086524	Oryzias latipes	68.22	0.00e+00	846.00
IUUC-Oga-088540	Otolemur garnettii	94.74	0.00e+00	1081.00
IUUC-Oar-089793	Ovis aries	91.34	0.00e+00	998.00
IUUC-Ptr-091154	Pan troglodytes	95.25	0.00e+00	1088.00
IUUC-Pan-092759	Papio anubis	95.08	0.00e+00	1085.00
IUUC-Psi-094008	Pelodiscus sinensis	87.95	0.00e+00	1061.00
IUUC-Pma-094593	Petromyzon marinus	47.20	3.00e-133	468.00
IUUC-Pfo-097409	Poecilia formosa	67.05	0.00e+00	804.00
IUUC-Pab-097946	Pongo abelii	83.36	0.00e+00	933.00
IUUC-Pca-100727	Procavia capensis	87.95	0.00e+00	983.00
IUUC-Pva-103211	Pteropus vampyrus	84.38	0.00e+00	1000.00
IUUC-Pgr-103603	Puccinia graminis	43.30	7.00e-73	268.00
IUUC-Ptt-103995	Puccinia triticina	44.14	4.00e-71	263.00
IUUC-Rno-105236	Rattus norvegicus	91.85	0.00e+00	1034.00
IUUC-Sha-106833	Sarcophilus harrisii	91.05	0.00e+00	1074.00
IUUC-Sar-113381	Sorex araneus	95.42	0.00e+00	1117.00
IUUC-Tgu-117143	Taeniopygia guttata	90.49	0.00e+00	1096.00
IUUC-Tru-118680	Takifugu rubripes	67.83	0.00e+00	829.00
IUUC-Tsy-119622	Tarsius syrichta	79.12	0.00e+00	830.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.83	0.00e+00	833.00
IUUC-Tbe-127656	Tupaia belangeri	88.64	8.00e-81	294.00
IUUC-Ttr-129171	Tursiops truncatus	95.42	0.00e+00	1080.00
IUUC-Xtr-132241	Xenopus tropicalis	79.15	0.00e+00	931.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence