iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006637

UUCD1 version

UUC-ArT-01636

Ensembl Protein ID

AT5G50870.2

UniProt Accession

Q9FI61; Q42045; UBC27_ARATH

Genbank Protein ID

AAY44866.1; ABG85247.1; BAB08733.1; AED96003.1; AAL38779.1; AAM20069.1; CAA81015.1

Protein Name

Ubiquitin-conjugating enzyme E2 27; E2 ubiquitin-conjugating enzyme 27; Ubiquitin carrier protein 27

Genbank Nucleotide ID

DQ027040; DQ677667; AB017063; CP002688; AY065303; AY096429; Z25704

Gene Name

UBC27; UBC1; At5g50870; K3K7.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G50870	AT5G50870.1	AT5G50870.1
AT5G50870	AT5G50870.2	AT5G50870.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UBA	UBA	16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	3.00e-40	138.1	6	130
UBD/Alpha-Helix/UBA	5.90e-06	27.1	164	200

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp.egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspal 96
           R++kel++ e+++  +gi++ p+++ +lt++  +i Gp +tpYegg+F+++i++p+ YPf+PPk++f tk++hPn++++ G++Cl+ilk  ++Wspal
   Q: 6    RIQKELQDCERNQDsSGIRVCPKSD-NLTRLTGTIPGPIGTPYEGGTFQIDITMPDGYPFEPPKMQFSTKVWHPNISSQsGAICLDILK--DQWSPAL 100
           99*******8877637899999999.9***************************************************99********9..******* PP
   S: 97   svesvllsiqsllaepnpesplneeaaell 126
           ++++ l+siq+ll+ p+p++p+++ +ae++
   Q: 101  TLKTALVSIQALLSAPEPKDPQDAVVAEQV 130
           **********************99988764 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyL 38
           ++e+k+  lveMGF + +++ a ++++++ + A+e L
   Q: 164  SLEEKVKRLVEMGFGDAQVRSAIESSGGDENLALEKL 200
           579*******************************987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MIDFSRIQKE LQDCERNQDS SGIRVCPKSD NLTRLTGTIP GPIGTPYEGG TFQIDITMPD 60
GYPFEPPKMQ FSTKVWHPNI SSQSGAICLD ILKDQWSPAL TLKTALVSIQ ALLSAPEPKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTATAATGG GCCTAGACTT TGGTTGATTT CGGTTCAACT TTAATTTTTG CCTTAATTGA 60
ATATTGAAGA AGTGACTGTT GGATAACTCC CTTAAGTCTT AAGATGCAAG AAAAGAAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

ath:AT5G50870

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	48.02	1.00e-52	198.00
IUUC-Aml-001286	Ailuropoda melanoleuca	46.86	1.00e-41	161.00
IUUC-Atr-003063	Amborella trichopoda	67.98	1.00e-65	241.00
IUUC-Apl-004122	Anas platyrhynchos	50.00	3.00e-39	154.00
IUUC-Aca-004565	Anolis carolinensis	50.00	2.00e-39	154.00
IUUC-Aly-006390	Arabidopsis lyrata	91.13	4.00e-108	382.00
IUUC-Ago-007714	Ashbya gossypii	43.52	8.00e-43	166.00
IUUC-Acl-008189	Aspergillus clavatus	59.06	3.00e-24	104.00
IUUC-Afl-008489	Aspergillus flavus	62.10	5.00e-25	107.00
IUUC-Afu-008850	Aspergillus fumigatus	59.84	3.00e-26	111.00
IUUC-Ani-009361	Aspergillus nidulans	52.63	5.00e-26	110.00
IUUC-Ang-009548	Aspergillus niger	46.94	1.00e-24	105.00
IUUC-Aor-010105	Aspergillus oryzae	62.10	5.00e-25	107.00
IUUC-Ate-010389	Aspergillus terreus	58.73	6.00e-26	110.00
IUUC-Ame-011454	Astyanax mexicanus	46.86	9.00e-42	162.00
IUUC-Bgr-012255	Blumeria graminis	48.41	6.00e-33	133.00
IUUC-Bta-012992	Bos taurus	46.86	1.00e-41	161.00
IUUC-Bci-013806	Botrytis cinerea	42.17	5.00e-34	137.00
IUUC-Bdi-015024	Brachypodium distachyon	63.29	2.00e-60	224.00
IUUC-Bol-015985	Brassica oleracea	87.68	1.00e-104	371.00
IUUC-Bra-016805	Brassica rapa	87.68	8.00e-105	371.00
IUUC-Cel-018353	Caenorhabditis elegans	47.74	4.00e-49	186.00
IUUC-Cja-019051	Callithrix jacchus	46.86	2.00e-41	161.00
IUUC-Cfa-020016	Canis familiaris	46.86	1.00e-41	161.00
IUUC-Cpo-022026	Cavia porcellus	46.86	1.00e-41	161.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	57.64	2.00e-51	194.00
IUUC-Csa-023059	Chlorocebus sabaeus	46.86	1.00e-41	161.00
IUUC-Cin-025598	Ciona intestinalis	45.54	2.00e-37	147.00
IUUC-Csv-025831	Ciona savignyi	49.44	2.00e-38	151.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	47.44	2.00e-38	151.00
IUUC-Cne-027068	Cryptococcus neoformans	40.91	6.00e-44	169.00
IUUC-Dre-028139	Danio rerio	46.86	9.00e-42	162.00
IUUC-Dno-029169	Dasypus novemcinctus	46.80	2.00e-39	154.00
IUUC-Dse-031335	Dothistroma septosporum	55.91	1.00e-37	149.00
IUUC-Dme-032003	Drosophila melanogaster	43.78	1.00e-39	155.00
IUUC-Ete-032868	Echinops telfairi	45.03	2.00e-28	117.00
IUUC-Eca-033428	Equus caballus	46.86	1.00e-41	161.00
IUUC-Fca-035366	Felis catus	46.86	1.00e-41	161.00
IUUC-Fal-037016	Ficedula albicollis	46.86	1.00e-41	161.00
IUUC-Fox-037969	Fusarium oxysporum	42.44	1.00e-40	158.00
IUUC-Fso-038296	Fusarium solani	42.86	2.00e-40	157.00
IUUC-Gmo-039135	Gadus morhua	46.86	3.00e-41	160.00
IUUC-Ggr-039768	Gaeumannomyces graminis	40.00	2.00e-31	128.00
IUUC-Gga-041018	Gallus gallus	46.86	2.00e-41	161.00
IUUC-Gac-041503	Gasterosteus aculeatus	46.86	1.00e-41	162.00
IUUC-Gma-043630	Glycine max	72.77	6.00e-87	312.00
IUUC-Ggo-045032	Gorilla gorilla	46.86	1.00e-41	161.00
IUUC-Hsa-046490	Homo sapiens	46.86	1.00e-41	161.00
IUUC-Hvu-047691	Hordeum vulgare	59.12	8.00e-26	108.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	46.86	1.00e-41	161.00
IUUC-Kpa-049297	Komagataella pastoris	42.78	9.00e-34	135.00
IUUC-Lch-050588	Latimeria chalumnae	52.63	1.00e-42	165.00
IUUC-Lpe-051070	Leersia perrieri	59.42	8.00e-57	212.00
IUUC-Loc-052549	Lepisosteus oculatus	46.86	2.00e-41	161.00
IUUC-Lma-052949	Leptosphaeria maculans	42.19	7.00e-40	156.00
IUUC-Laf-053688	Loxodonta africana	47.06	1.00e-39	155.00
IUUC-Mcc-055606	Macaca mulatta	46.86	1.00e-41	161.00
IUUC-Mor-056946	Magnaporthe oryzae	46.20	4.00e-29	120.00
IUUC-Mpo-057441	Magnaporthe poae	39.09	9.00e-31	125.00
IUUC-Mtr-058002	Medicago truncatula	71.78	2.00e-85	307.00
IUUC-Mla-059007	Melampsora laricipopulina	55.77	8.00e-49	186.00
IUUC-Mga-059254	Meleagris gallopavo	50.00	3.00e-39	153.00
IUUC-Mvi-060346	Microbotryum violaceum	42.67	6.00e-43	166.00
IUUC-Mmr-061211	Microcebus murinus	46.86	1.00e-41	161.00
IUUC-Mdo-062458	Monodelphis domestica	46.38	2.00e-39	154.00
IUUC-Mmu-063648	Mus musculus	46.86	1.00e-41	161.00
IUUC-Mac-065447	Musa acuminata	64.73	1.00e-66	244.00
IUUC-Mpu-066407	Mustela putorius furo	46.86	4.00e-41	160.00
IUUC-Mlu-067682	Myotis lucifugus	50.00	2.00e-39	154.00
IUUC-Nfi-068517	Neosartorya fischeri	45.23	2.00e-26	111.00
IUUC-Ncr-068749	Neurospora crassa	39.35	2.00e-40	158.00
IUUC-Nle-069712	Nomascus leucogenys	50.00	4.00e-39	153.00
IUUC-Opr-070651	Ochotona princeps	46.86	1.00e-41	161.00
IUUC-Ont-071595	Oreochromis niloticus	46.86	1.00e-41	162.00
IUUC-Oan-073058	Ornithorhynchus anatinus	50.00	8.00e-33	131.00
IUUC-Ocu-074939	Oryctolagus cuniculus	46.86	1.00e-41	161.00
IUUC-Oba-075530	Oryza barthii	59.71	2.00e-56	210.00
IUUC-Obr-076838	Oryza brachyantha	59.22	1.00e-56	211.00
IUUC-Ogl-077606	Oryza glaberrima	59.71	2.00e-56	210.00
IUUC-Ogu-078238	Oryza glumaepatula	59.71	2.00e-56	210.00
IUUC-Oin-079643	Oryza indica	59.71	2.00e-56	211.00
IUUC-Ome-081274	Oryza meridionalis	59.71	2.00e-56	210.00
IUUC-Oni-082651	Oryza nivara	59.71	2.00e-56	210.00
IUUC-Opu-083933	Oryza punctata	59.71	8.00e-57	212.00
IUUC-Oru-085054	Oryza rufipogon	59.71	2.00e-56	210.00
IUUC-Osa-085716	Oryza sativa	59.71	2.00e-56	211.00
IUUC-Ola-087043	Oryzias latipes	46.86	1.00e-41	162.00
IUUC-Olu-087846	Ostreococcus lucimarinus	51.50	2.00e-53	201.00
IUUC-Oga-088897	Otolemur garnettii	47.06	1.00e-39	155.00
IUUC-Oar-089673	Ovis aries	47.03	8.00e-40	155.00
IUUC-Ptr-091295	Pan troglodytes	46.86	1.00e-41	161.00
IUUC-Pan-092034	Papio anubis	46.88	3.00e-39	154.00
IUUC-Psi-093498	Pelodiscus sinensis	46.86	1.00e-41	161.00
IUUC-Pma-094115	Petromyzon marinus	46.86	2.00e-44	171.00
IUUC-Pno-095102	Phaeosphaeria nodorum	43.46	3.00e-42	164.00
IUUC-Ppa-095326	Physcomitrella patens	61.95	5.00e-62	229.00
IUUC-Pfo-096940	Poecilia formosa	45.41	5.00e-42	162.00
IUUC-Pab-098279	Pongo abelii	46.86	1.00e-41	161.00
IUUC-Pop-099543	Populus trichocarpa	76.10	2.00e-90	323.00
IUUC-Pca-100782	Procavia capensis	46.86	3.00e-40	157.00
IUUC-Ppe-101789	Prunus persica	72.82	5.00e-79	286.00
IUUC-Pgr-103643	Puccinia graminis	56.13	1.00e-47	182.00
IUUC-Ptt-103772	Puccinia triticina	54.55	2.00e-46	178.00
IUUC-Pte-104370	Pyrenophora teres	51.59	2.00e-40	157.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	51.59	3.00e-40	157.00
IUUC-Rno-104984	Rattus norvegicus	46.86	1.00e-41	161.00
IUUC-Sce-106394	Saccharomyces cerevisiae	49.69	2.00e-34	138.00
IUUC-Sha-106721	Sarcophilus harrisii	46.38	2.00e-41	161.00
IUUC-Sja-107866	Schizosaccharomyces japonicus	47.06	8.00e-47	179.00
IUUC-Spo-108209	Schizosaccharomyces pombe	46.15	2.00e-46	178.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	50.65	3.00e-33	134.00
IUUC-Smo-109656	Selaginella moellendorffii	66.18	3.00e-64	236.00
IUUC-Sit-110639	Setaria italica	64.08	5.00e-62	229.00
IUUC-Sly-110978	Solanum lycopersicum	69.27	4.00e-83	299.00
IUUC-Stu-112088	Solanum tuberosum	69.76	1.00e-83	301.00
IUUC-Sbi-113986	Sorghum bicolor	63.59	1.00e-61	228.00
IUUC-Sre-115046	Sporisorium reilianum	53.75	2.00e-46	177.00
IUUC-Ssc-116314	Sus scrofa	46.86	1.00e-41	161.00
IUUC-Tgu-117427	Taeniopygia guttata	50.00	2.00e-39	154.00
IUUC-Tru-118618	Takifugu rubripes	44.93	2.00e-41	161.00
IUUC-Tsy-119208	Tarsius syrichta	46.86	4.00e-41	160.00
IUUC-Tni-120673	Tetraodon nigroviridis	45.89	2.00e-47	181.00
IUUC-Tca-121446	Theobroma cacao	74.63	1.00e-89	320.00
IUUC-Tre-122053	Trichoderma reesei	51.59	3.00e-35	141.00
IUUC-Tvi-122533	Trichoderma virens	52.38	4.00e-36	144.00
IUUC-Tae-125119	Triticum aestivum	60.39	4.00e-56	209.00
IUUC-Tme-127024	Tuber melanosporum	46.07	1.00e-43	169.00
IUUC-Tbe-127752	Tupaia belangeri	47.29	4.00e-40	156.00
IUUC-Ttr-128287	Tursiops truncatus	50.00	2.00e-39	154.00
IUUC-Uma-129512	Ustilago maydis	54.38	3.00e-47	180.00
IUUC-Vda-129947	Verticillium dahliae	57.14	1.00e-38	152.00
IUUC-Vpa-130481	Vicugna pacos	46.86	2.00e-41	161.00
IUUC-Vvi-131429	Vitis vinifera	71.64	8.00e-86	308.00
IUUC-Xtr-132710	Xenopus tropicalis	35.89	4.00e-31	126.00
IUUC-Xma-134165	Xiphophorus maculatus	46.38	3.00e-41	160.00
IUUC-Yli-134523	Yarrowia lipolytica	42.63	4.00e-35	140.00
IUUC-Zma-135733	Zea mays	64.25	3.00e-63	233.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence