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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063914
Ensembl Protein ID ENSMUSP00000013130.8
UniProt Accession Q9ERG2; STRN3_MOUSE
Genbank Protein ID AAG24454.1
Protein Name Striatin-3; Cell cycle autoantigen SG2NA; S/G2 antigen
Genbank Nucleotide ID AF307777
Gene Name Strn3; Gs2na; Sg2na
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000020954.15 ENSMUST00000013130.13 ENSMUSP00000013130.8
ENSMUSG00000020954.15 ENSMUST00000169503.2 ENSMUSP00000130184.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.80e-26 90.4 584 614
UBD/Beta-Prp 1.30e-54 186.5 573 793
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclafsd..tllvsGsdDgtikvWDl 30
           Htd v++la+s+  + l+s+s Dgti++W++
   Q: 584  HTDAVWGLAYSGikNQLLSCSADGTIRLWNP 614
           **********666689*************95 PP
   

   UBD/Beta-Prp
   S: 40   ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsv..lslsfsp.sgdklvsGshdrtirvwdle 124
           ++  l  +l  h+++v+ + +s  ++ l+++s D+ti++w+++ + +cv t++g ++    +s++f   +  ++v+  +   + ++dle
   Q: 573  ESNVLAGTLVAHTDAVWGLAYSGIKNQLLSCSADGTIRLWNPQeKLPCVCTYNGDKEHGipTSVDFIGcDPAHMVTSFNTGSAVIYDLE 661
           455678899*******************************887699*******7655541245555554449***************** PP
   S: 125  tgqclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklw 207
           t q l           + +  +n vv+hp+  + ++++ Dr ++++d ktgk+++ +   h d+v+sl++d+ng +l+sgs+d +++lw
   Q: 662  TSQSLVMlssqvdSGLQSSNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMIHSMVA-HLDAVTSLAVDPNGIYLMSGSHDCSIRLW 749
           *****9988996633334556899999**99**************************98.***************************** PP
   S: 208  dlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           +l +++cv++ ++h+    + +++v+f+p + +++s+++D   +
   Q: 750  NLDSKTCVQEITAHRkkldESIYDVAFHPSKAYIASAGADALAK 793
           ***************99999*******************97655 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity).
 Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity).
Protein Sequence
(Fasta)
MDELAGGGGG GQGMAAPPRP QQGPGGNLSL PPGANGAPGG GGPPAAEAAG PPAGPELSRP 60
QQYTIPGILH YIQHEWARFE MERAHWEVER AELQARIAFL QGERKGQENL KKDLVRRIKM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063914|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGTGAGTGA GACGGGCAGA TGGAGGAGGT ACCGTAATGG CGGCGGCCGG CAGCTCCCTG 60
CTCTGATCCG CGGCAAGCAC ACGGCAACGA CCCCCTCCCC GGCCGTCTCC CGGCCGGCCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063914|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0112--Calmodulin-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08232--Striatin
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0005794--C:Golgi apparatus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000159--C:protein phosphatase type 2A complex
GO:0070016--F:armadillo repeat domain binding
GO:0032403--F:protein complex binding
GO:0051721--F:protein phosphatase 2A binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0033147--P:negative regulation of intracellular estrogen receptor signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032355--P:response to estradiol
KEGG mmu:94186
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002046 Ailuropoda melanoleuca 94.74 0.00e+00 1338.00
IUUC-Apl-003472 Anas platyrhynchos 93.36 0.00e+00 1251.00
IUUC-Aca-005286 Anolis carolinensis 92.62 0.00e+00 1302.00
IUUC-Afl-008585 Aspergillus flavus 27.88 2.00e-36 147.00
IUUC-Ani-009405 Aspergillus nidulans 30.19 3.00e-36 147.00
IUUC-Aor-009982 Aspergillus oryzae 27.88 3.00e-36 147.00
IUUC-Bgr-012143 Blumeria graminis 25.89 6.00e-35 142.00
IUUC-Bta-012797 Bos taurus 94.73 0.00e+00 1390.00
IUUC-Bci-013742 Botrytis cinerea 25.23 2.00e-35 144.00
IUUC-Cel-018443 Caenorhabditis elegans 39.68 1.00e-101 363.00
IUUC-Cja-018786 Callithrix jacchus 95.56 0.00e+00 1361.00
IUUC-Cfa-021098 Canis familiaris 92.61 0.00e+00 1306.00
IUUC-Cpo-022357 Cavia porcellus 93.55 0.00e+00 1323.00
IUUC-Csa-023725 Chlorocebus sabaeus 95.95 0.00e+00 1363.00
IUUC-Cho-024338 Choloepus hoffmanni 90.04 0.00e+00 1180.00
IUUC-Cin-025167 Ciona intestinalis 49.73 0.00e+00 655.00
IUUC-Csv-026143 Ciona savignyi 51.60 0.00e+00 678.00
IUUC-Cgl-026487 Colletotrichum gloeosporioides 25.89 3.00e-31 130.00
IUUC-Cne-026783 Cryptococcus neoformans 32.51 1.00e-56 215.00
IUUC-Dre-027566 Danio rerio 79.61 0.00e+00 697.00
IUUC-Dno-029926 Dasypus novemcinctus 95.15 0.00e+00 1357.00
IUUC-Dse-031486 Dothistroma septosporum 27.48 9.00e-38 152.00
IUUC-Dme-032158 Drosophila melanogaster 63.32 7.00e-143 501.00
IUUC-Ete-032770 Echinops telfairi 81.00 0.00e+00 1126.00
IUUC-Eca-033309 Equus caballus 95.30 0.00e+00 1348.00
IUUC-Eeu-034939 Erinaceus europaeus 92.13 0.00e+00 995.00
IUUC-Fca-035719 Felis catus 92.54 0.00e+00 1216.00
IUUC-Fal-037408 Ficedula albicollis 92.95 0.00e+00 1195.00
IUUC-Fox-037678 Fusarium oxysporum 25.86 1.00e-35 144.00
IUUC-Fso-038364 Fusarium solani 25.81 6.00e-37 149.00
IUUC-Gmo-039653 Gadus morhua 63.77 0.00e+00 883.00
IUUC-Ggr-039846 Gaeumannomyces graminis 25.79 1.00e-33 138.00
IUUC-Gga-041218 Gallus gallus 93.96 0.00e+00 1335.00
IUUC-Gac-042142 Gasterosteus aculeatus 72.46 0.00e+00 1069.00
IUUC-Ggo-045607 Gorilla gorilla 78.84 0.00e+00 1040.00
IUUC-Hsa-045717 Homo sapiens 96.09 0.00e+00 1371.00
IUUC-Itr-048177 Ictidomys tridecemlineatus 97.50 0.00e+00 967.00
IUUC-Lch-050441 Latimeria chalumnae 90.05 0.00e+00 1342.00
IUUC-Loc-052193 Lepisosteus oculatus 86.36 0.00e+00 1269.00
IUUC-Lma-053183 Leptosphaeria maculans 28.83 1.00e-39 158.00
IUUC-Laf-053964 Loxodonta africana 94.35 0.00e+00 1344.00
IUUC-Mcc-055639 Macaca mulatta 95.96 0.00e+00 1365.00
IUUC-Mor-057148 Magnaporthe oryzae 42.31 1.00e-17 85.50
IUUC-Mpo-057337 Magnaporthe poae 24.80 4.00e-30 127.00
IUUC-Mla-058988 Melampsora laricipopulina 34.57 9.00e-65 242.00
IUUC-Mmr-061084 Microcebus murinus 96.09 0.00e+00 1370.00
IUUC-Mdo-063016 Monodelphis domestica 95.15 0.00e+00 1358.00
IUUC-Mpu-066348 Mustela putorius furo 86.54 0.00e+00 1226.00
IUUC-Mlu-067303 Myotis lucifugus 93.27 0.00e+00 1296.00
IUUC-Nle-070032 Nomascus leucogenys 96.09 0.00e+00 1372.00
IUUC-Opr-070496 Ochotona princeps 90.83 0.00e+00 652.00
IUUC-Ont-072075 Oreochromis niloticus 71.22 0.00e+00 1047.00
IUUC-Oan-072822 Ornithorhynchus anatinus 92.94 0.00e+00 1195.00
IUUC-Ocu-073876 Oryctolagus cuniculus 92.65 0.00e+00 1324.00
IUUC-Ola-086321 Oryzias latipes 69.81 0.00e+00 1002.00
IUUC-Oga-088045 Otolemur garnettii 96.08 0.00e+00 1362.00
IUUC-Oar-089737 Ovis aries 95.18 0.00e+00 1272.00
IUUC-Ptr-090871 Pan troglodytes 96.30 0.00e+00 1293.00
IUUC-Pan-092139 Papio anubis 95.02 0.00e+00 1268.00
IUUC-Psi-093424 Pelodiscus sinensis 93.06 0.00e+00 1263.00
IUUC-Pma-094286 Petromyzon marinus 70.47 0.00e+00 680.00
IUUC-Pno-094905 Phaeosphaeria nodorum 28.16 2.00e-35 144.00
IUUC-Pfo-096564 Poecilia formosa 72.63 0.00e+00 1077.00
IUUC-Pab-098626 Pongo abelii 96.09 0.00e+00 1407.00
IUUC-Pva-102445 Pteropus vampyrus 89.08 0.00e+00 1260.00
IUUC-Ptt-103828 Puccinia triticina 36.81 3.00e-48 187.00
IUUC-Pte-104374 Pyrenophora teres 28.11 1.00e-33 138.00
IUUC-Pyt-104568 Pyrenophora triticirepentis 27.65 1.00e-36 148.00
IUUC-Rno-105999 Rattus norvegicus 97.74 0.00e+00 1449.00
IUUC-Sha-106786 Sarcophilus harrisii 93.47 0.00e+00 1277.00
IUUC-Ssl-108495 Sclerotinia sclerotiorum 26.08 5.00e-35 143.00
IUUC-Sar-113296 Sorex araneus 75.04 0.00e+00 847.00
IUUC-Tgu-117199 Taeniopygia guttata 89.41 0.00e+00 1169.00
IUUC-Tsy-119356 Tarsius syrichta 80.24 0.00e+00 957.00
IUUC-Tre-122113 Trichoderma reesei 27.27 2.00e-38 154.00
IUUC-Tvi-122312 Trichoderma virens 26.13 2.00e-36 147.00
IUUC-Tme-126990 Tuber melanosporum 26.63 5.00e-35 143.00
IUUC-Tbe-127691 Tupaia belangeri 80.31 0.00e+00 783.00
IUUC-Ttr-128600 Tursiops truncatus 88.53 0.00e+00 1245.00
Created Date 25-Jun-2017

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