iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090663

UUCD1 version

UUC-PaT-00673

Ensembl Protein ID

ENSPTRP00000033454.4

UniProt Accession

H2QV59; H2QV59_PANTR

Genbank Protein ID

JAA02856.1; JAA19352.1; JAA27006.1; JAA35151.1

Protein Name

Leucine-rich repeats and WD repeat domain containing 1

Genbank Nucleotide ID

AC211007; GABF01002793; GABD01006094; GABE01009588

Gene Name

LRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000019539.4	ENSPTRT00000036187.4	ENSPTRP00000033454.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-07	30.8	391	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWD 29
           H+  +  l+f   ++t+l ++s+D+ i +WD
   Q: 391  HKKAIATLCFspaHETHLFTASYDKRIILWD 421
           888899999*98666**************** PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MGPLSARLLM QRGRPKSDRL GKIRSLDLSG LELLSEHLDP KLLCRLTQLQ ELDLSNNHLE 60
TLPDNLGLSH LRVLRCANNQ LGDVTALCQF PKLEELSLEG NPFLTVNDNL KVSFLLPTLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTCCGGTC GTTAACGCCC ACGGGCTCGC GCGGCGCCGC CTCCTGGGCT CAGTTACCGC 60
GGACGCCAGT ACCGGGCTCC AGGAGACGCA GGGCGACGCC ACACGTCGGG GTGGCCGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR025875--Leu-rich_rpt_4
IPR003591--Leu-rich_rpt_typical-subtyp
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS51450--LRR
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12799--LRR_4

SMART

SM00369--LRR_TYP
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0000776--C:kinetochore
GO:0005664--C:nuclear origin of replication recognition complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005721--C:pericentric heterochromatin
GO:0031933--C:telomeric heterochromatin
GO:0003682--F:chromatin binding
GO:0008327--F:methyl-CpG binding
GO:0006325--P:chromatin organization
GO:0071169--P:establishment of protein localization to chromatin

KEGG

ptr:107972025; ptr:463928

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001948	Ailuropoda melanoleuca	84.53	0.00e+00	678.00
IUUC-Bta-012858	Bos taurus	79.35	0.00e+00	999.00
IUUC-Cja-019702	Callithrix jacchus	95.52	0.00e+00	1170.00
IUUC-Cfa-020910	Canis familiaris	87.38	0.00e+00	1077.00
IUUC-Cpo-022523	Cavia porcellus	82.36	0.00e+00	1081.00
IUUC-Csa-023359	Chlorocebus sabaeus	97.06	0.00e+00	1226.00
IUUC-Dno-029426	Dasypus novemcinctus	86.90	0.00e+00	1063.00
IUUC-Dor-030654	Dipodomys ordii	81.33	0.00e+00	827.00
IUUC-Dme-031714	Drosophila melanogaster	27.59	3.00e-06	45.80
IUUC-Eca-034035	Equus caballus	88.39	0.00e+00	1088.00
IUUC-Eeu-034711	Erinaceus europaeus	76.43	1.00e-170	593.00
IUUC-Gmo-039096	Gadus morhua	35.01	2.00e-107	383.00
IUUC-Ggo-044714	Gorilla gorilla	99.69	0.00e+00	1216.00
IUUC-Hsa-046826	Homo sapiens	99.69	0.00e+00	1214.00
IUUC-Laf-054449	Loxodonta africana	85.82	0.00e+00	1074.00
IUUC-Mcc-055193	Macaca mulatta	97.68	0.00e+00	1195.00
IUUC-Mmr-061572	Microcebus murinus	88.39	0.00e+00	1116.00
IUUC-Mmu-063240	Mus musculus	77.50	0.00e+00	952.00
IUUC-Mpu-066295	Mustela putorius furo	87.21	0.00e+00	1078.00
IUUC-Mlu-067766	Myotis lucifugus	86.15	0.00e+00	1084.00
IUUC-Nle-069200	Nomascus leucogenys	94.75	0.00e+00	1112.00
IUUC-Ola-086965	Oryzias latipes	38.91	1.00e-86	314.00
IUUC-Oga-088411	Otolemur garnettii	81.88	0.00e+00	1090.00
IUUC-Oar-089415	Ovis aries	80.43	0.00e+00	948.00
IUUC-Pan-092467	Papio anubis	95.69	0.00e+00	1160.00
IUUC-Pab-098479	Pongo abelii	97.53	0.00e+00	1199.00
IUUC-Pca-101023	Procavia capensis	75.23	0.00e+00	884.00
IUUC-Pva-102812	Pteropus vampyrus	83.44	0.00e+00	1050.00
IUUC-Rno-105469	Rattus norvegicus	78.05	0.00e+00	970.00
IUUC-Ssc-115884	Sus scrofa	86.90	0.00e+00	1105.00
IUUC-Tbe-127247	Tupaia belangeri	88.93	6.00e-139	487.00
IUUC-Ttr-128723	Tursiops truncatus	85.91	0.00e+00	1072.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence