iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013296

Ensembl Protein ID

ENSBTAP00000009023.4

UniProt Accession

F1MZ13; F1MZ13_BOVIN

Genbank Protein ID

ENSBTAP00000009023

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02052410

Gene Name

OTUD7A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000006868.4	ENSBTAT00000009023.4	ENSBTAP00000009023.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	4.20e-40	137.5	151	332
UBD/ZnF/ZnF_A20	1.40e-15	57.0	848	882

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al++++r+ +++++ k+++++++++++k           e+e++++ kl+++e    
   Q: 151  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKALYTMMRTGAEREALKRRWRWQQTQQNKesglvyteeewEREWTELLKLASSEprth 239
           6899*********************************************************************************8877 PP
   S: 75   .ak.g.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
            +k g                 ee+h+f+La+iL+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++a
   Q: 240  fSKnGgsgggmdnaedpvyeslEEFHVFVLAHILRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPPNRcHCSPLVLAYDQAHFSA 328
           7444478899******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 329  LVSM 332
           *986 PP

UBD/ZnF/ZnF_A20

   S: 2    pskllCkk.gCgfYGnpetngyCSkCyreelrrrr 35
           p++++C++ +C+fYG++et++yCS+Cyreelrrrr
   Q: 848  PAQRRCQReNCAFYGRAETEHYCSYCYREELRRRR 882
           99*******************************97 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

GKNWDLTAAL SDYEQLRQVH TANLPPVFNE GRCPKQPERE PPPPGHTAER PCLPRQDDIA 60
QEKRLSRGIS HASSAIVSLA RSHVASECSS EQFPLEMPIY TFQLPDLSVY SEDFRSFVER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAAAACT GGGACCTCAC GGCCGCTCTG AGTGACTATG AGCAGCTCCG ACAGGTGCAC 60
ACAGCCAACC TGCCACCTGT GTTCAACGAG GGCAGGTGCC CCAAACAGCC TGAGCGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

SMART

SM00259--ZnF_A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001551	Ailuropoda melanoleuca	96.98	0.00e+00	1040.00
IUUC-Apl-003825	Anas platyrhynchos	70.41	0.00e+00	1113.00
IUUC-Aca-004392	Anolis carolinensis	74.53	0.00e+00	1133.00
IUUC-Ame-011052	Astyanax mexicanus	69.51	0.00e+00	1042.00
IUUC-Cja-019141	Callithrix jacchus	93.40	0.00e+00	975.00
IUUC-Cfa-020447	Canis familiaris	96.20	0.00e+00	1027.00
IUUC-Cpo-022059	Cavia porcellus	94.57	0.00e+00	875.00
IUUC-Csa-023263	Chlorocebus sabaeus	96.67	0.00e+00	1022.00
IUUC-Cho-024611	Choloepus hoffmanni	86.71	4.00e-166	578.00
IUUC-Dre-028617	Danio rerio	67.72	0.00e+00	1048.00
IUUC-Dno-029121	Dasypus novemcinctus	91.47	0.00e+00	1003.00
IUUC-Ete-033068	Echinops telfairi	74.51	0.00e+00	1046.00
IUUC-Eca-034413	Equus caballus	96.57	0.00e+00	984.00
IUUC-Fca-036487	Felis catus	93.14	0.00e+00	988.00
IUUC-Fal-037145	Ficedula albicollis	75.56	0.00e+00	1145.00
IUUC-Gmo-038786	Gadus morhua	64.34	0.00e+00	908.00
IUUC-Gga-040512	Gallus gallus	73.37	0.00e+00	1132.00
IUUC-Gac-041599	Gasterosteus aculeatus	66.26	0.00e+00	995.00
IUUC-Ggo-044819	Gorilla gorilla	91.00	0.00e+00	1275.00
IUUC-Hsa-046781	Homo sapiens	90.09	0.00e+00	1269.00
IUUC-Itr-047999	Ictidomys tridecemlineatus	88.40	0.00e+00	759.00
IUUC-Lch-050666	Latimeria chalumnae	72.99	0.00e+00	1136.00
IUUC-Loc-052841	Lepisosteus oculatus	70.43	0.00e+00	1091.00
IUUC-Laf-053437	Loxodonta africana	88.73	0.00e+00	998.00
IUUC-Mcc-055353	Macaca mulatta	88.95	0.00e+00	1262.00
IUUC-Mga-059741	Meleagris gallopavo	73.15	0.00e+00	1129.00
IUUC-Mmr-061437	Microcebus murinus	90.90	0.00e+00	1282.00
IUUC-Mdo-061907	Monodelphis domestica	76.62	0.00e+00	1151.00
IUUC-Mmu-064074	Mus musculus	88.14	0.00e+00	1228.00
IUUC-Mpu-066004	Mustela putorius furo	94.12	0.00e+00	1013.00
IUUC-Nle-069182	Nomascus leucogenys	95.20	0.00e+00	1061.00
IUUC-Opr-070701	Ochotona princeps	87.93	0.00e+00	927.00
IUUC-Ont-072431	Oreochromis niloticus	76.13	0.00e+00	907.00
IUUC-Oan-073235	Ornithorhynchus anatinus	73.55	0.00e+00	1061.00
IUUC-Ocu-073935	Oryctolagus cuniculus	96.21	0.00e+00	964.00
IUUC-Ola-087026	Oryzias latipes	67.00	0.00e+00	1036.00
IUUC-Oga-088249	Otolemur garnettii	94.58	0.00e+00	1072.00
IUUC-Oar-089476	Ovis aries	98.74	0.00e+00	1348.00
IUUC-Ptr-090548	Pan troglodytes	96.26	0.00e+00	928.00
IUUC-Pan-092616	Papio anubis	87.80	0.00e+00	1228.00
IUUC-Psi-093126	Pelodiscus sinensis	76.42	0.00e+00	1118.00
IUUC-Pfo-096785	Poecilia formosa	65.38	0.00e+00	1013.00
IUUC-Pab-098336	Pongo abelii	90.91	0.00e+00	1128.00
IUUC-Pca-100206	Procavia capensis	80.11	0.00e+00	1105.00
IUUC-Rno-105483	Rattus norvegicus	86.98	0.00e+00	964.00
IUUC-Sha-106617	Sarcophilus harrisii	87.48	0.00e+00	913.00
IUUC-Ssc-115415	Sus scrofa	90.14	0.00e+00	1201.00
IUUC-Tgu-117218	Taeniopygia guttata	87.20	0.00e+00	1004.00
IUUC-Tru-118720	Takifugu rubripes	84.44	0.00e+00	769.00
IUUC-Tni-120795	Tetraodon nigroviridis	79.68	0.00e+00	874.00
IUUC-Xtr-132158	Xenopus tropicalis	69.45	0.00e+00	1115.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence