iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115415

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP102314

Gene Name

OTUD7A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000004840.2	ENSSSCT00000005342.2	ENSSSCP00000005210.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	4.60e-40	137.5	152	333

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al++++r+ +++++ k+++++++++++k           e+e++++ kl+++e    
   Q: 152  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKALYTMMRTGAEREALKRRWRWQQTQQNKesglvyteeewEREWTELLKLASSEprth 240
           6899*********************************************************************************8877 PP
   S: 75   .ak.g.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
            +k g                 ee+h+f+La+iL+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++a
   Q: 241  fSKnGgtgggvdnaedpvyeslEEFHVFVLAHILRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPPNRcHCSPLVLAYDQAHFSA 329
           7444377899******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 330  LVSM 333
           *986 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

GKNWDLTAAL SDYEQLRQVH TANLPPVFNE GRCPKQPERE PPPPGHTAER PCLPRQEDIA 60
QAEKRLSRGI SHASSAIVSL ARSHVASECS SEQFPLEMPI YTFQLPDLSV YSEDFRSFVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAGAACT GGGACCTGAC GGCCGCTCTG AGTGACTATG AGCAGCTCCG ACAAGTGCAC 60
ACAGCCAACC TGCCACCTGT GTTCAACGAG GGCAGGTGTC CCAAGCAGCC CGAGCGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050727--P:regulation of inflammatory response
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001551	Ailuropoda melanoleuca	96.83	0.00e+00	1034.00
IUUC-Apl-003825	Anas platyrhynchos	84.09	0.00e+00	991.00
IUUC-Aca-004392	Anolis carolinensis	73.56	0.00e+00	1090.00
IUUC-Ame-011052	Astyanax mexicanus	69.07	0.00e+00	1032.00
IUUC-Bta-013296	Bos taurus	93.76	0.00e+00	1255.00
IUUC-Cja-019141	Callithrix jacchus	93.25	0.00e+00	967.00
IUUC-Cfa-020447	Canis familiaris	95.73	0.00e+00	1019.00
IUUC-Cpo-022059	Cavia porcellus	94.41	0.00e+00	866.00
IUUC-Csa-023263	Chlorocebus sabaeus	96.51	0.00e+00	1013.00
IUUC-Cho-024611	Choloepus hoffmanni	86.42	5.00e-166	578.00
IUUC-Dre-028617	Danio rerio	67.36	0.00e+00	1034.00
IUUC-Dno-029121	Dasypus novemcinctus	91.80	0.00e+00	1004.00
IUUC-Ete-033068	Echinops telfairi	71.95	0.00e+00	1025.00
IUUC-Eca-034413	Equus caballus	96.41	0.00e+00	976.00
IUUC-Fca-036487	Felis catus	93.80	0.00e+00	980.00
IUUC-Fal-037145	Ficedula albicollis	76.27	0.00e+00	1119.00
IUUC-Gmo-038786	Gadus morhua	71.27	0.00e+00	794.00
IUUC-Gga-040512	Gallus gallus	74.89	0.00e+00	1114.00
IUUC-Gac-041599	Gasterosteus aculeatus	66.41	0.00e+00	978.00
IUUC-Ggo-044819	Gorilla gorilla	90.15	0.00e+00	1223.00
IUUC-Hsa-046781	Homo sapiens	90.03	0.00e+00	1217.00
IUUC-Lch-050666	Latimeria chalumnae	72.38	0.00e+00	1112.00
IUUC-Loc-052841	Lepisosteus oculatus	69.75	0.00e+00	1056.00
IUUC-Laf-053437	Loxodonta africana	88.25	0.00e+00	993.00
IUUC-Mcc-055353	Macaca mulatta	88.32	0.00e+00	1208.00
IUUC-Mga-059741	Meleagris gallopavo	82.29	0.00e+00	1006.00
IUUC-Mmr-061437	Microcebus murinus	95.43	0.00e+00	1060.00
IUUC-Mdo-061907	Monodelphis domestica	75.86	0.00e+00	1118.00
IUUC-Mmu-064074	Mus musculus	87.53	0.00e+00	1197.00
IUUC-Mpu-066004	Mustela putorius furo	94.13	0.00e+00	1008.00
IUUC-Nle-069182	Nomascus leucogenys	93.75	0.00e+00	1042.00
IUUC-Opr-070701	Ochotona princeps	87.09	0.00e+00	912.00
IUUC-Ont-072431	Oreochromis niloticus	87.16	0.00e+00	802.00
IUUC-Oan-073235	Ornithorhynchus anatinus	86.56	0.00e+00	941.00
IUUC-Ocu-073935	Oryctolagus cuniculus	96.06	0.00e+00	959.00
IUUC-Ola-087026	Oryzias latipes	79.28	0.00e+00	919.00
IUUC-Oga-088249	Otolemur garnettii	94.43	0.00e+00	1066.00
IUUC-Oar-089476	Ovis aries	92.74	0.00e+00	1262.00
IUUC-Ptr-090548	Pan troglodytes	96.10	0.00e+00	921.00
IUUC-Pan-092616	Papio anubis	87.83	0.00e+00	1181.00
IUUC-Psi-093126	Pelodiscus sinensis	75.44	0.00e+00	1084.00
IUUC-Pfo-096785	Poecilia formosa	79.12	0.00e+00	892.00
IUUC-Pab-098336	Pongo abelii	90.18	0.00e+00	1108.00
IUUC-Pca-100206	Procavia capensis	79.68	0.00e+00	1070.00
IUUC-Rno-105483	Rattus norvegicus	84.93	0.00e+00	928.00
IUUC-Sha-106617	Sarcophilus harrisii	89.00	0.00e+00	910.00
IUUC-Tgu-117218	Taeniopygia guttata	87.38	0.00e+00	1001.00
IUUC-Tru-118720	Takifugu rubripes	85.09	0.00e+00	768.00
IUUC-Tni-120795	Tetraodon nigroviridis	80.03	0.00e+00	874.00
IUUC-Tur-126060	Triticum urartu	27.03	9.80e-01	28.10
IUUC-Xtr-132158	Xenopus tropicalis	68.65	0.00e+00	1090.00
IUUC-Xma-133941	Xiphophorus maculatus	77.39	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence