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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Sce-106338
Ensembl Protein ID YDL188C
UniProt Accession P23595; D6VRG5; PP2A2_YEAST
Genbank Protein ID CAA39703.1; AAB04032.1; CAA41659.1; CAA58259.1; CAA98765.1; DAA11675.1
Protein Name Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
Genbank Nucleotide ID X56262; M60317; X58857; X83276; Z74236; BK006938
Gene Name PPH22; SIS4; YDL188C; D1271
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YDL188C YDL188C YDL188C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMUniProtPHOSIDA
BioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UIM 76.16 2.00e-143 506.00 IUUC-Hsa-046871
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Binds 2 manganese ions per subunit.
 Binds 2 manganese ions per subunit.
Protein Sequence
(Fasta)
MDMEIDDPMH GSDEDQLSPT LDEDMNSDDG KNNTKARSND EDTDEELEDF NFKPGSSGIA 60
DHKSSKPLKL TNTNINQLDQ WIEHLSKCEP LSEDDVARLC KMAVDVLQFE ENVKPINVPV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106338|UBD,UIM|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATATGG AAATTGATGA CCCTATGCAT GGTTCAGATG AAGATCAATT ATCACCGACT 60
CTCGACGAAG ACATGAATAG TGATGACGGC AAAAATAATA CGAAGGCGCG TTCTAATGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106338|UBD,UIM|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0464--Manganese
KW-0479--Metal-binding
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-0904--Protein phosphatase
KW-1185--Reference proteome
Interpro

IPR004843--Calcineurin-like_PHP_ApaH
IPR029052--Metallo-depent_PP-like
IPR006186--Ser/Thr-sp_prot-phosphatase
PROSITE

PS00125--SER_THR_PHOSPHATASE
Pfam

PF00149--Metallophos
PRINTS

PR00114--STPHPHTASE
SMART

SM00156--PP2Ac
Gene Ontology

GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0034399--C:nuclear periphery
GO:0046872--F:metal ion binding
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0007015--P:actin filament organization
GO:0007117--P:budding cell bud growth
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0007094--P:mitotic spindle assembly checkpoint
GO:2000198--P:negative regulation of ribonucleoprotein complex localization
GO:0070262--P:peptidyl-serine dephosphorylation
GO:0006470--P:protein dephosphorylation
GO:0006417--P:regulation of translation
KEGG sce:YDL188C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000073 Aegilops tauschii 73.67 2.00e-138 483.00
IUUC-Aml-001862 Ailuropoda melanoleuca 76.16 3.00e-145 505.00
IUUC-Atr-002565 Amborella trichopoda 73.33 4.00e-139 484.00
IUUC-Apl-004163 Anas platyrhynchos 74.92 2.00e-143 499.00
IUUC-Aca-005038 Anolis carolinensis 75.83 3.00e-145 505.00
IUUC-Aly-005921 Arabidopsis lyrata 73.67 1.00e-140 489.00
IUUC-Ath-007164 Arabidopsis thaliana 73.00 4.00e-139 484.00
IUUC-Ani-009239 Aspergillus nidulans 20.83 1.30e+00 25.40
IUUC-Ame-010907 Astyanax mexicanus 76.16 3.00e-145 505.00
IUUC-Bgr-012186 Blumeria graminis 73.35 3.00e-147 512.00
IUUC-Bta-013583 Bos taurus 76.16 3.00e-145 505.00
IUUC-Bci-013884 Botrytis cinerea 77.05 1.00e-147 513.00
IUUC-Bdi-014993 Brachypodium distachyon 73.67 2.00e-137 479.00
IUUC-Bra-017702 Brassica rapa 74.00 1.00e-140 489.00
IUUC-Cja-019549 Callithrix jacchus 76.16 3.00e-145 505.00
IUUC-Cfa-020295 Canis familiaris 76.16 3.00e-145 505.00
IUUC-Cpo-022311 Cavia porcellus 76.16 3.00e-145 505.00
IUUC-Cre-022625 Chlamydomonas reinhardtii 71.99 3.00e-137 478.00
IUUC-Csa-023283 Chlorocebus sabaeus 76.16 3.00e-145 505.00
IUUC-Cho-024478 Choloepus hoffmanni 39.02 1.80e-01 28.90
IUUC-Cin-025581 Ciona intestinalis 76.67 1.00e-144 503.00
IUUC-Csv-026026 Ciona savignyi 77.70 2.00e-130 456.00
IUUC-Cgl-026758 Colletotrichum gloeosporioides 76.10 1.00e-148 516.00
IUUC-Cne-026997 Cryptococcus neoformans 74.50 5.00e-143 498.00
IUUC-Cme-027101 Cyanidioschyzon merolae 71.56 5.00e-144 501.00
IUUC-Dre-027487 Danio rerio 76.16 9.00e-146 507.00
IUUC-Dno-028872 Dasypus novemcinctus 76.16 3.00e-145 505.00
IUUC-Ete-032859 Echinops telfairi 76.16 3.00e-145 505.00
IUUC-Eca-033874 Equus caballus 39.02 1.70e-01 28.90
IUUC-Fca-036395 Felis catus 76.16 3.00e-145 505.00
IUUC-Fal-036826 Ficedula albicollis 78.55 1.00e-135 473.00
IUUC-Fox-037783 Fusarium oxysporum 75.62 5.00e-150 521.00
IUUC-Fso-038215 Fusarium solani 75.94 6.00e-150 521.00
IUUC-Gmo-038520 Gadus morhua 76.24 7.00e-144 501.00
IUUC-Ggr-039745 Gaeumannomyces graminis 77.92 4.00e-149 518.00
IUUC-Gga-040663 Gallus gallus 75.83 3.00e-145 505.00
IUUC-Gac-042221 Gasterosteus aculeatus 75.17 7.00e-145 504.00
IUUC-Gma-042753 Glycine max 73.67 4.00e-139 484.00
IUUC-Ggo-044960 Gorilla gorilla 76.16 3.00e-145 505.00
IUUC-Hsa-046871 Homo sapiens 76.16 3.00e-145 505.00
IUUC-Itr-048646 Ictidomys tridecemlineatus 76.16 3.00e-145 505.00
IUUC-Kpa-049311 Komagataella pastoris 89.17 2.00e-177 612.00
IUUC-Lch-050295 Latimeria chalumnae 75.83 3.00e-145 505.00
IUUC-Lpe-051261 Leersia perrieri 73.67 2.00e-139 486.00
IUUC-Loc-052336 Lepisosteus oculatus 76.16 2.00e-145 506.00
IUUC-Lma-053211 Leptosphaeria maculans 73.39 2.00e-149 519.00
IUUC-Laf-053835 Loxodonta africana 76.16 3.00e-145 505.00
IUUC-Mcc-055756 Macaca mulatta 76.16 3.00e-145 505.00
IUUC-Meu-056068 Macropus eugenii 58.47 2.00e-98 349.00
IUUC-Mor-057272 Magnaporthe oryzae 75.70 4.00e-149 518.00
IUUC-Mpo-057478 Magnaporthe poae 77.92 3.00e-149 518.00
IUUC-Mtr-057736 Medicago truncatula 74.67 4.00e-140 488.00
IUUC-Mla-059001 Melampsora laricipopulina 74.83 1.00e-145 506.00
IUUC-Mga-059904 Meleagris gallopavo 76.90 2.00e-139 486.00
IUUC-Mvi-060467 Microbotryum violaceum 75.25 8.00e-145 503.00
IUUC-Mmr-060867 Microcebus murinus 76.16 3.00e-145 505.00
IUUC-Mdo-062353 Monodelphis domestica 76.16 3.00e-145 505.00
IUUC-Mmu-064204 Mus musculus 76.16 2.00e-145 506.00
IUUC-Mac-064924 Musa acuminata 74.33 2.00e-140 489.00
IUUC-Mpu-066183 Mustela putorius furo 76.16 3.00e-145 505.00
IUUC-Mlu-067115 Myotis lucifugus 76.16 5.00e-145 504.00
IUUC-Ncr-068958 Neurospora crassa 76.27 5.00e-150 521.00
IUUC-Nle-069365 Nomascus leucogenys 76.16 3.00e-145 505.00
IUUC-Opr-071012 Ochotona princeps 76.16 3.00e-145 505.00
IUUC-Ont-071469 Oreochromis niloticus 76.16 7.00e-146 507.00
IUUC-Oan-072869 Ornithorhynchus anatinus 77.78 6.00e-136 474.00
IUUC-Ocu-074394 Oryctolagus cuniculus 76.16 3.00e-145 505.00
IUUC-Oba-075432 Oryza barthii 73.33 8.00e-139 484.00
IUUC-Ogl-077436 Oryza glaberrima 73.00 7.00e-138 481.00
IUUC-Ogu-078351 Oryza glumaepatula 73.33 8.00e-139 484.00
IUUC-Oin-080218 Oryza indica 73.00 6.00e-138 481.00
IUUC-Olo-080223 Oryza longistaminata 73.00 7.00e-138 481.00
IUUC-Ome-081581 Oryza meridionalis 73.00 6.00e-138 481.00
IUUC-Oni-082094 Oryza nivara 73.00 6.00e-138 481.00
IUUC-Opu-083544 Oryza punctata 73.33 2.00e-138 483.00
IUUC-Oru-084975 Oryza rufipogon 73.00 6.00e-138 481.00
IUUC-Osa-085945 Oryza sativa 73.00 6.00e-138 481.00
IUUC-Ola-087141 Oryzias latipes 75.83 1.00e-145 506.00
IUUC-Oga-087919 Otolemur garnettii 76.16 3.00e-145 505.00
IUUC-Oar-089240 Ovis aries 78.55 1.00e-135 473.00
IUUC-Ptr-091367 Pan troglodytes 75.75 9.00e-144 500.00
IUUC-Pan-091956 Papio anubis 76.16 3.00e-145 505.00
IUUC-Psi-094099 Pelodiscus sinensis 76.16 1.00e-145 506.00
IUUC-Pma-094369 Petromyzon marinus 77.71 2.00e-73 265.00
IUUC-Pno-094872 Phaeosphaeria nodorum 67.30 1.00e-127 446.00
IUUC-Ppa-095520 Physcomitrella patens 76.00 3.00e-143 498.00
IUUC-Pfo-097359 Poecilia formosa 75.49 4.00e-146 508.00
IUUC-Pab-097981 Pongo abelii 39.02 8.80e-02 28.90
IUUC-Pop-099210 Populus trichocarpa 75.00 6.00e-142 494.00
IUUC-Pca-100122 Procavia capensis 66.23 5.00e-120 421.00
IUUC-Ppe-101822 Prunus persica 74.33 2.00e-140 489.00
IUUC-Pva-102237 Pteropus vampyrus 67.88 4.00e-124 435.00
IUUC-Pgr-103259 Puccinia graminis 74.34 1.00e-145 506.00
IUUC-Pte-104116 Pyrenophora teres 73.39 2.00e-149 519.00
IUUC-Pyt-104768 Pyrenophora triticirepentis 73.39 2.00e-149 519.00
IUUC-Rno-104853 Rattus norvegicus 76.16 2.00e-145 506.00
IUUC-Sha-107562 Sarcophilus harrisii 76.16 7.00e-146 507.00
IUUC-Sja-107705 Schizosaccharomyces japonicus 75.40 2.00e-148 516.00
IUUC-Spo-108240 Schizosaccharomyces pombe 75.49 8.00e-146 507.00
IUUC-Smo-109421 Selaginella moellendorffii 75.83 1.00e-143 499.00
IUUC-Sit-110313 Setaria italica 73.00 1.00e-138 483.00
IUUC-Sly-111492 Solanum lycopersicum 74.00 2.00e-139 486.00
IUUC-Stu-112108 Solanum tuberosum 74.00 2.00e-139 486.00
IUUC-Sar-113253 Sorex araneus 75.59 8.00e-140 487.00
IUUC-Sbi-114125 Sorghum bicolor 73.67 3.00e-138 482.00
IUUC-Sre-115054 Sporisorium reilianum 74.43 7.00e-145 504.00
IUUC-Ssc-116207 Sus scrofa 39.02 1.60e-01 28.90
IUUC-Tgu-117419 Taeniopygia guttata 75.83 3.00e-145 505.00
IUUC-Tru-117531 Takifugu rubripes 76.16 4.00e-146 508.00
IUUC-Tsy-119543 Tarsius syrichta 76.16 3.00e-145 505.00
IUUC-Tni-120904 Tetraodon nigroviridis 75.83 3.00e-145 505.00
IUUC-Tca-120941 Theobroma cacao 75.00 1.00e-141 493.00
IUUC-Tre-121939 Trichoderma reesei 75.24 2.00e-148 515.00
IUUC-Tvi-122516 Trichoderma virens 75.00 7.00e-149 517.00
IUUC-Tae-124897 Triticum aestivum 73.67 2.00e-138 483.00
IUUC-Tbe-127639 Tupaia belangeri 76.16 3.00e-145 505.00
IUUC-Ttr-128718 Tursiops truncatus 75.83 3.00e-145 505.00
IUUC-Uma-129470 Ustilago maydis 74.43 7.00e-145 504.00
IUUC-Vpa-130513 Vicugna pacos 39.02 1.60e-01 28.90
IUUC-Vvi-131390 Vitis vinifera 74.00 6.00e-141 491.00
IUUC-Xtr-132784 Xenopus tropicalis 76.16 1.00e-145 506.00
IUUC-Xma-133450 Xiphophorus maculatus 76.16 6.00e-145 504.00
Created Date 25-Jun-2017

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